A ligand that binds to a receptor and alters the receptor state resulting in a biological response.
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One Liner
The combined effect of two or more drugs is equal to the sum of their indivisual effect
Additive effect i.e paracetamol + ibuprofen as analgesics
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More Questions & Answers
Use of dimecaprol in arsenic poisoning is an example of
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When two or more drugs on simultaneous administration show effect greater than that of either drug alone
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The amount of change in measured output per unit change in input.
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When the effect of one drug is decreased or abolished in the presence of another drug
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Adsorption of alkaloids by activated charcoal is an example of
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Antagonist binds with the same receptor as the agonist and inhibits its effect
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When two drugs act at different receptors or by different machanisms on the same physiological system and produce opposite effect
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Explanation:
CYP3A4 is involved in the metabolism of
majority of drugs and is also expressed
extrahepatically. In fact, poor bioavailability of
many drugs is attributed to the drug metabolism
by CYP3A4 in gastrointestinal tract.
