Antagonist binds with the same receptor as the agonist and inhibits its effect
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The enhancement of action of one drug by another inactive drug
Potentiation (supra-additive effect)
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Adsorption of alkaloids by activated charcoal is an example of
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When both agonist and antagonist binds reversibly on the same site of the receptor
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The percent of dose entering the systemic circulation after administration of a given dosage form.
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When two or more drugs on simultaneous administration show effect greater than that of either drug alone
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The study of poisons, their actions, detection, prevention and the treatment of poisoning
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When two drugs act at different receptors or by different machanisms on the same physiological system and produce opposite effect
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cancer derived from germ cell which are commonly found in the brain of young ages.
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Explanation:
Chemical antagonism does not involve any
receptors. Protamine is a positively charged
protein at physiological pH and thus
antagonizes the effects of Heparin which is
negatively charged at physiological pH.
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