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binding of Morphine and Naloxone to the Opioid receptors

competitive antagonism
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This question belongs to the set "Revision of Pharmacology, some basic points (one liners)". Click below to read detailed notes and attempt the full quiz.

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Try These Similar MCQs

  • A Raynaud’s disease
  • B Infection
  • C Heart attack
  • D Epilepsy
  • A Hyoscine hydrobromide
  • B Morphine sulfate
  • C Diclofenac sodium
  • D Quinine dihydrochloride
  • A CYP378A
  • B CYP4B2
  • C CYP3A4
  • D CYP256
Explanation: CYP3A4 is involved in the metabolism of majority of drugs and is also expressed extrahepatically. In fact, poor bioavailability of many drugs is attributed to the drug metabolism by CYP3A4 in gastrointestinal tract.
  • A Heparin & Protamine
  • B Protamine & Zinc
  • C Heparin & Prothrombin
  • D All the above
Explanation: Chemical antagonism does not involve any receptors. Protamine is a positively charged protein at physiological pH and thus antagonizes the effects of Heparin which is negatively charged at physiological pH.
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