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Antagonist binds with the same receptor as the agonist and inhibits its effect

receptor anatgonism
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This question belongs to the set "Revision of Pharmacology, some basic points (one liners)". Click below to read detailed notes and attempt the full quiz.

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  • A Canal of Schlemm
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  • A Enalapril
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  • A CYP378A
  • B CYP4B2
  • C CYP3A4
  • D CYP256
Explanation: CYP3A4 is involved in the metabolism of majority of drugs and is also expressed extrahepatically. In fact, poor bioavailability of many drugs is attributed to the drug metabolism by CYP3A4 in gastrointestinal tract.
  • A Undergoes little first-pass metabolism
  • B Is incompletely absorbed
  • C Is freely water soluble
  • D Is completely absorbed
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