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When two or more drugs on simultaneous administration show effect greater than that of either drug alone

Synergism (e.g. Sulphamethoxazole + trimethoprim)

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This question belongs to the set "Revision of Pharmacology, some basic points (one liners)". Click below to read detailed notes and attempt the full quiz.

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Explanation: CYP3A4 is involved in the metabolism of majority of drugs and is also expressed extrahepatically. In fact, poor bioavailability of many drugs is attributed to the drug metabolism by CYP3A4 in gastrointestinal tract.

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