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One Liner

Use of dimecaprol in arsenic poisoning is an example of

Chemical antagonism

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This question belongs to the set "Revision of Pharmacology, some basic points (one liners)". Click below to read detailed notes and attempt the full quiz.

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  • A Bethanechol
  • B Butyrylcholine
  • C Methacholine
  • D Benzoylcholine
  • A Dapsone
  • B Meperidine
  • C Phenytoin
  • D Chlorpheniramine
Explanation: N-oxidation is involved in the metabolism of dapsone, meperidine and chloramphenicol. Metabolism of phenytoin involves oxidative Ndealkylation.
  • A Heparin & Protamine
  • B Protamine & Zinc
  • C Heparin & Prothrombin
  • D All the above
Explanation: Chemical antagonism does not involve any receptors. Protamine is a positively charged protein at physiological pH and thus antagonizes the effects of Heparin which is negatively charged at physiological pH.
  • A It has additional α1 blocking property
  • B It is a selective βS1 blocker
  • C It does not undergo first pass metabolism
  • D All of the above
  • A Tolerance
  • B Physical dependence
  • C Psychological dependence
  • D Idiosyncrasy
  • A Albumin
  • B acid glycoprotein
  • C Weak acids
  • D Heparin & Protamine
Explanation: Glycoprotein binds to basic drugs and albumin binds to many acidic drugs and a small number of basic drugs.

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