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An inverse agonist is a ligand that by binding to a receptor reduces the fraction of receptors in an active conformation, thereby reducing basal activity.

Inverse Agonist
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This question belongs to the set "Pharmacology Chapter 1 Revision: Key One-Liner Questions for Pharmacist Exams". Click below to read detailed notes and attempt the full quiz.

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  • A Weak acids
  • B Strong acids
  • C Weak Bases
  • D None of the above
Explanation: because of enhanced disassociation weak acids are excreted faster in basic (not acidic) urine.
  • A Passive diffusion
  • B Facilitated diffusion
  • C Active transport
  • D Pinocytosis
  • A Increases volume of distribution of the drug
  • B Generally makes the drug long acting
  • C Facilitates glomerular filtration of the drug
  • D Minimises drug interactions
  • A Adrenergic α1 agonists
  • B Adrenergic α1 antagonists
  • C Adrenergic α2 antagonists
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  • A Neuromuscular junction
  • B Postganglionic parasympathetic
  • C Adrenal medulla
  • D Autonomic ganglia
  • A Carrier is involved
  • B It is against concentration gradient
  • C Energy is required
  • D All of the above
Explanation: Facilitated diffusion differs from active transport in that it does not require energy source and it carries the transport in the direction of electrochemical gradient.
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