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One Liner

A form of experiment in which the participants are, to some degree, kept ignorant of the nature and doses of materials administered as specific parts of the experiment.

Blind Experiment
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This question belongs to the set "Pharmacology Chapter 1 Revision: Key One-Liner Questions for Pharmacist Exams". Click below to read detailed notes and attempt the full quiz.

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  • A Adrenergic α1 agonists
  • B Adrenergic α1 antagonists
  • C Adrenergic α2 antagonists
  • D Adrenergic α2 agonists
  • A CYP378A
  • B CYP4B2
  • C CYP3A4
  • D CYP256
Explanation: CYP3A4 is involved in the metabolism of majority of drugs and is also expressed extrahepatically. In fact, poor bioavailability of many drugs is attributed to the drug metabolism by CYP3A4 in gastrointestinal tract.
  • A Is more painful
  • B Produces faster response
  • C Is unsuitable for depot preparations
  • D Carries greater risk of anaphylactic reaction
  • A Heparin & Protamine
  • B Protamine & Zinc
  • C Heparin & Prothrombin
  • D All the above
Explanation: Chemical antagonism does not involve any receptors. Protamine is a positively charged protein at physiological pH and thus antagonizes the effects of Heparin which is negatively charged at physiological pH.
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