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One Liner

A ligand that binds to a receptor and alters the receptor state resulting in a biological response.

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This question belongs to the set "Pharmacology Chapter 1 Revision: Key One-Liner Questions for Pharmacist Exams". Click below to read detailed notes and attempt the full quiz.

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Try These Similar MCQs

  • A Is more painful
  • B Produces faster response
  • C Is unsuitable for depot preparations
  • D Carries greater risk of anaphylactic reaction
  • A Neuromuscular junction
  • B Postganglionic parasympathetic
  • C Adrenal medulla
  • D Autonomic ganglia
  • A Dapsone
  • B Meperidine
  • C Phenytoin
  • D Chlorpheniramine
Explanation: N-oxidation is involved in the metabolism of dapsone, meperidine and chloramphenicol. Metabolism of phenytoin involves oxidative Ndealkylation.
  • A CYP378A
  • B CYP4B2
  • C CYP3A4
  • D CYP256
Explanation: CYP3A4 is involved in the metabolism of majority of drugs and is also expressed extrahepatically. In fact, poor bioavailability of many drugs is attributed to the drug metabolism by CYP3A4 in gastrointestinal tract.
  • A Nature of the base used in the formulation
  • B Lipid solubility of the drug
  • C Molecular weight of the drug
  • D Site of application
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