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Explain the sliding filament theory in detail with role of proteins, calcium and ATP.

The sliding filament theory explains how muscles contract: - Nerve impulse releases acetylcholine at neuromuscular junction. - Calcium ions released from sarcoplasmic reticulum bind troponin. - Actin sites exposed, myosin heads attach forming cross-bridges. - ATP hydrolysis provides energy, pulling actin filaments inward. - Sarcomere shortens, causing contraction. - When impulse ends, calcium reabsorbed, muscles relax.

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This question belongs to the set "Musculoskeletal System – Important Questions and Answers (LAQs)". Click below to read detailed notes and attempt the full quiz.

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