Test Attempted : Classification Of Drugs In Pharmacology Aptitude Test
Total Questions : 30
Attempted : 30
Skipped : 0
Correct Responses : 19
Incorrect Responses : 11
Marks Obtained
Q.1. Suganril is common brand name for:
Your Response : (b) Piroxican
Correct Response : b) Piroxican
Marks : 1
Answer:
(b) Piroxican
Explanation: Piroxicam is used to relieve the symptoms of rheumatoid and osteoarthritis.
Q.2. Which one of these is μ-opioid agonist?
Your Response : (a) Pethidine
Correct Response : a) Pethidine
Marks : 1
Answer:
(a) Pethidine
Explanation: Pethidine is a phenyl piperidine that is also a strong agonist of μ-opioid receptor.
Q.3. Levodopa is amino acid precursor of -
Your Response : (c) Norepinephrine
Correct Response : d) All of these
Marks : 0
Answer:
(d) All of these
Explanation: levo dopa is the amino acid precursor for dopamine and also for adrenaline and noradrenaline.
Q.4. The most potent CNS stimulant among xanthine bases are-
Your Response : (b) Caffeine
Correct Response : b) Caffeine
Marks : 1
Answer:
(b) Caffeine
Explanation: Caffeine is the most potent CNS stimulant.
Q.5. Chlorpromazine is useful in the treatment of -
Your Response : (b) Schizophrenia
Correct Response : b) Schizophrenia
Marks : 1
Answer:
(b) Schizophrenia
Explanation: Chlorpromazine (CPZ) is a dopamine antagonist of the typical antipsychotic class of medications possessing additional anti-adrenergic, anti-serotonergic, anti-cholinergic, and anti-histaminergic properties used to treat schizophrenia.
Q.6. Amlodepine Lowers blood pressure by-
Your Response : (a) Inhibition of calcium influx
Correct Response : a) Inhibition of calcium influx
Marks : 1
Answer:
(a) Inhibition of calcium influx
Explanation: Amlodepine is a long acting dihydropyridine type calcium channel blocker.
Q.7. Cholestyramine is useful in the treatment of -
Your Response : (c) Hyper lipoproteinemia
Correct Response : c) Hyper lipoproteinemia
Marks : 1
Answer:
(c) Hyper lipoproteinemia
Explanation: Cholestyramine is a bile acid sequestrant.
Q.8. Clofibrate mainly Lowers the -
Your Response : (b) VLDL
Correct Response : b) VLDL
Marks : 1
Answer:
(b) VLDL
Explanation: Clofibrate is used for controlling cholesterol and triglycerides levels. It changes VLDL to LDL.
Q.9. Lovastatin is useful in -
Your Response : (a) High blood pressure
Correct Response : c) Hyper lipoproteinemia
Marks : 0
Answer:
(c) Hyper lipoproteinemia
Explanation: Lovastatin is a naturally occurring Drug in food, which controls blood cholesterol level.
Q.10. Oral anticoagulants act by antagonising the actions of -
Your Response : (a) Calcium ion
Correct Response : c) Vitamin K
Marks : 0
Answer:
(c) Vitamin K
Explanation: vitamin K is a fat soluble vitamin and is required for post translational modification.
Q.11. Glucocorticoid are used in the treatment of :
Your Response : (a) Inflammation
Correct Response : b) Inflammation and allergy
Marks : 0
Answer:
(b) Inflammation and allergy
Explanation: Glucocorticoids are the part of the feedback mechanism in the immune system that turns immune activity (inflammation).
Q.12. The sulphonamides are :
Your Response : (b) Bacteriostatic in nature
Correct Response : b) Bacteriostatic in nature
Marks : 1
Answer:
(b) Bacteriostatic in nature
Explanation: A Sulphonamide displaces bilirubin. It is competitive inhibitor of enzyme DHPS, cause inhibition of folate synthesis and cause bacteriostatic action.
Q.13. Tetracycline act by -
Your Response : (b) Interfering in cell wall synthesis
Correct Response : a) Inhibition of protein synthesis
Marks : 0
Answer:
(a) Inhibition of protein synthesis
Explanation: Tetracycline is a broad spectrum antibiotic which reduces the growth of bacteria by inhibiting the protein synthesis. it binds with the 30s subunit of microbial ribosomes, to inhibit protein synthesis.
Q.14. Nystatin is principally effective in:
Your Response : (c) Cryptococcus histoplasma
Correct Response : a) Candidia albicans
Marks : 0
Answer:
(a) Candidia albicans
Explanation: Nystatin is a polyene antifungal medication derived from streptomyces noursei.
Q.15. Pyridoxine is administered with isoniazid to minimise the:
Your Response : (c) Nephrotoxicity
Correct Response : c) Nephrotoxicity
Marks : 1
Answer:
(c) Nephrotoxicity
Explanation: Pyridoxine is also called vitamin B6, assist in the balancing of sodium and potassium as well as promoting RBC.
Q.16. Which one of these combination is used in Chloroquine resistance malaria?
Your Response : (b) Pyrimethamine + sulphadoxine
Correct Response : b) Pyrimethamine + sulphadoxine
Marks : 1
Answer:
(b) Pyrimethamine + sulphadoxine
Explanation: Sulphadoxine + Pyrimethamine (Fansidar) is a combination antimalarial containing the sulphonamide antibiotic sulphadoxine and the anti-protozoal pyrimethamine.
Q.17. Which one of the enzyme is used in the treatment of cancer?
Your Response : (a) L- asparginase
Correct Response : a) L- asparginase
Marks : 1
Answer:
(a) L- asparginase
Explanation: L- asparginase catalyzes the hydrolysis of asparagines to aspartic acid.
Q.18. Eserine acts by -
Your Response : (c) Drug-enzyme interactions
Correct Response : c) Drug-enzyme interactions
Marks : 1
Answer:
(c) Drug-enzyme interactions
Explanation: Eserine is another term for physostigmine is a highly toxic parasympathomimetic alkaloid.
Q.19. Desferrioxamine is a :
Your Response : (a) Chelating agent
Correct Response : a) Chelating agent
Marks : 1
Answer:
(a) Chelating agent
Explanation: Desferrioxamine is a bacterial siderophore produced by the actinobateria, Streptomyces pilosos.
Q.20. Sodium valproate prevent the epileptic seizure by -
Your Response : (b) Preventing influx of sodium
Correct Response : b) Preventing influx of sodium
Marks : 1
Answer:
(b) Preventing influx of sodium
Explanation: Sodium valproate used in epilepsy, Anorexia, and bipolar disorder.
Q.21. Which one of these is used with hyoscine to induce Twilight sleep?
Your Response : (a) Pentazocine
Correct Response : b) Pethidine
Marks : 0
Answer:
(b) Pethidine
Explanation: Hyoscine is also known as levo-duboisine, tropane alkaloid.
Q.22. Ergot preparations are useful in migraine due to its-
Your Response : (c) α -receptors blocking action
Correct Response : b) Vasoconstriction action
Marks : 0
Answer:
(b) Vasoconstriction action
Q.23. Which one of these is a major tranquilizer?
Your Response : (a) Phenelzine
Correct Response : c) Trifluoperazine
Marks : 0
Answer:
(c) Trifluoperazine
Explanation: trifluoperazine is a drug from phenothiazine chemical class is atypical antipsychotic drug.
Q.24. Which one is a cholinomimetic agent?
Your Response : (a) Atropine
Correct Response : d) Acetylcholine
Marks : 0
Answer:
(d) Acetylcholine
Explanation: Acetylcholine mimics the action of the cholinergic system.
Q.25. Testosterone is not orally active because?
Your Response : (d) Rapid oxidation of 17-hydroxy group to ketones
Correct Response : d) Rapid oxidation of 17-hydroxy group to ketones
Marks : 1
Answer:
(d) Rapid oxidation of 17-hydroxy group to ketones
Explanation: Testosterone is an androgenic steroid hormone, responsible for male characteristics.
Q.26. Which one of the following drug shows antiplatelet activity?
Your Response : (b) Nifedipine
Correct Response : d) Dipyridamole
Marks : 0
Answer:
(d) Dipyridamole
Explanation: Dipyridamole inhibits Thrombus formation.
Q.27. Nociceptors are associated with:
Your Response : (b) Pain
Correct Response : b) Pain
Marks : 1
Answer:
(b) Pain
Explanation: A Nociceptor is a receptor of a sensory neuron (nerve cell) that responds to potentially damaging stimuli by sending signals to the spinal cord and brain. This process called nociception usually causes the perception of pain.
Q.28. Drug that shows selective antagonistic selective H1 antagonistic action?
Your Response : (a) Chlorpheniramine
Correct Response : a) Chlorpheniramine
Marks : 1
Answer:
(a) Chlorpheniramine
Explanation: Chlorpheniramine is a first-generation alkylamine and anti-histamine for H1.
Cimetidine and ranitidine are H2 antagonists and inhibit stomach acid production.
Thioperamide is a selective H3 antagonist, and also capable of crossing the Blood-brain barrier.
Q.29. Which one is the alkylating anticancer drug?
Your Response : (c) Thiotepa
Correct Response : c) Thiotepa
Marks : 1
Answer:
(c) Thiotepa
Explanation: Thiotepa is an organophosphorus compound, is an alkylating anticancer drug.
Q.30. Which one is a HMGC A reductase inhibitor?
Your Response : (a) Rhabdomylosis
Correct Response : a) Rhabdomylosis
Marks : 1
Answer:
(a) Rhabdomylosis
Explanation: Rhabdomyolysis is a condition in which damaged skeletal muscle tissue breaks down rapidly.