RRB PH UT17 – Medicinal Chemistry Practice Test 2: SAR of Cardiovascular & Chemotherapeutic Agents

About this Assessment

About This Practice Test:

This online practice test delivers an authoritative, high-yield evaluation of Medicinal Chemistry aligned with the standard Pharmacy Council of India (PCI) B.Pharm/Pharm.D degree syllabus and standard compendia. Mastering the Structure-Activity Relationships (SAR), chemical synthesis pathways, and molecular pharmacophores of cardiovascular agents and major chemotherapeutic drugs—including Sulfonamides, Ciprofloxacin, Isoniazid, Chloroquine, Atenolol, Diazepam, and Metformin—is essential for pharmaceutical analysis, active pharmaceutical ingredient (API) production, and clinical dosage safety. Completing this timed CBT simulation reinforces structural mechanisms, eliminates medicinal chemistry traps, and prepares candidates for the competitive single-stage computer-based test.

Syllabus Covered:

Sulfonamides SAR & Synthesis: p-ABSC condensation, N_1 heteroaromatic ring pK_a optimization, and dihydropteroate synthase inhibitionFluoroquinolone Architecture: Ciprofloxacin IUPAC naming, C6 fluorine atom lipophilicity, and C7 piperazine spectrum modulationAnti-Tubercular & Antimalarial Chemistry: Isoniazid hydrazine synthesis, chloroquine 4,7-dichloroquinoline core, novaldiamine coupling, and hemozoin biocrystallizationCardiovascular Medicinal Chemistry: Atenolol aryloxypropanolamine synthesis from epichlorohydrin, hydrophilic blood-brain barrier exclusion, and nifedipine Hantzsch synthesisSedative-Hypnotics & Biguanides: Diazepam 1,4-benzodiazepine Sternbach synthesis, 7-chloro SAR, and metformin dicyandiamide addition kinetics

Applicable Examinations:RRB Paramedical Recruitment (Pharmacist Entry Grade)Central Health Boards: DSSSB Pharmacist, ESIC Healthcare Cadres, AIIMS Paramedical, CGHSState Paramedical & Health Recruitment Boards (State PSCs, DME, and State Pharmacy Recruitment Tests)

Test Instructions & Features:30 Questions | Timed Online Test | Detailed Explanations for Every Question | Instant Scorecard & Performance Analysis

Written & Verified by Prakash Joshi

Expert Faculty

Prakash Joshi is a pharmacy professional and Zoology graduate with an interest in life sciences, biology, and competitive exam preparation. Combining his pharmacy background with his academic knowledge of Zoology, he contributes to the development of educational content, practice questions, and exam-oriented study materials at SoloTutes. His work focuses on simplifying complex concepts, providing accurate and useful learning resources, and helping students prepare effectively for competitive examinations. Through SoloTutes, he aims to make quality educational content accessible to aspirants across India.

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