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The study of poisons, their actions, detection, prevention and the treatment of poisoning

Toxicology
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  • A Weak acids
  • B Strong acids
  • C Weak Bases
  • D None of the above
Explanation: because of enhanced disassociation weak acids are excreted faster in basic (not acidic) urine.
  • A Dapsone
  • B Meperidine
  • C Phenytoin
  • D Chlorpheniramine
Explanation: N-oxidation is involved in the metabolism of dapsone, meperidine and chloramphenicol. Metabolism of phenytoin involves oxidative Ndealkylation.
  • A Passive diffusion
  • B Facilitated diffusion
  • C Active transport
  • D Pinocytosis
  • A Highly plasma protein bound drugs
  • B Depot preparations
  • C Highly lipid soluble drugs
  • D Poorly lipid soluble drugs
  • A CYP378A
  • B CYP4B2
  • C CYP3A4
  • D CYP256
Explanation: CYP3A4 is involved in the metabolism of majority of drugs and is also expressed extrahepatically. In fact, poor bioavailability of many drugs is attributed to the drug metabolism by CYP3A4 in gastrointestinal tract.
  • A Neuromuscular junction
  • B Postganglionic parasympathetic
  • C Adrenal medulla
  • D Autonomic ganglia
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