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One Liner

The study of poisons, their actions, detection, prevention and the treatment of poisoning

Toxicology
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  • A Albumin
  • B acid glycoprotein
  • C Weak acids
  • D Heparin & Protamine
Explanation: Glycoprotein binds to basic drugs and albumin binds to many acidic drugs and a small number of basic drugs.
  • A Increases volume of distribution of the drug
  • B Generally makes the drug long acting
  • C Facilitates glomerular filtration of the drug
  • D Minimises drug interactions
  • A Colon
  • B Gastric fundus
  • C Bladder trigone
  • D Major bronchi
  • A Carrier is involved
  • B It is against concentration gradient
  • C Energy is required
  • D All of the above
Explanation: Facilitated diffusion differs from active transport in that it does not require energy source and it carries the transport in the direction of electrochemical gradient.
  • A Heparin & Protamine
  • B Protamine & Zinc
  • C Heparin & Prothrombin
  • D All the above
Explanation: Chemical antagonism does not involve any receptors. Protamine is a positively charged protein at physiological pH and thus antagonizes the effects of Heparin which is negatively charged at physiological pH.
  • A Weak acids
  • B Strong acids
  • C Weak Bases
  • D None of the above
Explanation: because of enhanced disassociation weak acids are excreted faster in basic (not acidic) urine.
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