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The science that deals with thr effect of drugs on living system

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This question belongs to the set "General Pharmacology questions (one Liners) ". Click below to read detailed notes and attempt the full quiz.

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  • A Weak acids
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  • C Weak Bases
  • D None of the above
Explanation: because of enhanced disassociation weak acids are excreted faster in basic (not acidic) urine.
  • A It has additional α1 blocking property
  • B It is a selective βS1 blocker
  • C It does not undergo first pass metabolism
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  • A CYP378A
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  • C CYP3A4
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Explanation: CYP3A4 is involved in the metabolism of majority of drugs and is also expressed extrahepatically. In fact, poor bioavailability of many drugs is attributed to the drug metabolism by CYP3A4 in gastrointestinal tract.
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