This practice test includes objective questions (MCQs) from pharmaceutical organic chemistry (pharma chemistry 2) for D.Pharma and B.pharma students. These questions are very helpful for competitive as well as (objective questions based) university exams.
Practice Test #1 | Pharmaceutical Chemistry-II (organic)
Score: 0 / 30
Questions
Q1. Diflunisal is a diflourophenyl derivative of -
Diflunisal is an analgesic drug, a derivative of salicylic acid. Brand name dolobid.
Q2. Drug used in gout is -
Indomethacin is the drug of choice in gout. It is one among the synthetic drug.
Q3. Oxyphenbutazone is active metabolite of following -
Phenylbutazone is metabolised in liver to oxyphenebutazone, which also pharmacologically active.
Q4. Carbomal, used in mild insomnia is a -
Carbomol is belongs to the class monoureides and it is used for mild sleep disorder (insomnia).
Q5. Cocaine is rarely used due to its -
Use of cocaine is restricted due to its addiction (habit forming properties)
Q6. Largactil is a a common name for -
Chlorpromazine is belongs to antipsychotic class (dopamine antagonist)
Q7. Which drug is preferred to give to bed wetted children?
Imipramine is a Tricyclic antidepressant drug used for bed wetting.
Q8. Which one of these drug is mono-amine oxidase (MAO) inhibitor?
MAO inhibitors are used in depression. They includes tranylcypromine, phenelgine, isocarboxazide, linezolid etc.
Q9. Caffeine is a -
Caffeine is 1,3,7-trimethyl xanthene, theophylline is 1,3-dimethyl xanthene and theobromine is 1,3- dimethyl xanthene.
Q10. Parkinsonism occurs due to -
The loss of dopamine in brain is cause for parkinson's disease.
Q11. Naphazoline is used in -
Naphazoline is a sympathomimetic agent. It is used as nasal decongestion agent.
Q12. Hyoscine (scopolamine) differs structurally from atropine -
Scopolamine and atropine both are tropane alkaloids. Presence of epoxide linkage between carbon 6 and 7 is the structural difference between these two. (See image below)
Q13. Quinidine acts as antiarrhythmic drug by -
Quinidine is a stereoisomer of quinine. It acts by blocking sodium channels.
Q14. Propranolol, atenolol, and metoprolol are similar in structure due to possession of-
The side chain is same in metaprolol, atenolol, and propranolol. All these three are β -blockers.
Q15. Mannitol acts as diuretic by-
Mannitol (manna sugar) is used clinically as diuretic and acts as osmotic agents (osmotherapy).
Q16. Sulphonylureas act as oral hypoglycaemic agent by -
Sulphonylureas are the class of anti-diabetic drugs (type 2 diabetes) they act by increasing insulin release from beta cells of pancreases.
Q17. Antithyroid drugs decrease the synthesis of thyroxine by -
Antithyroid drugs (carbimazole, methimazole, and propyl thiouracil) act by inhibiting iodination of thyroglobulin.
Q18. Which one of these is an anabolic steroid?
Stanozolol, danozol, nandrolone, metenolone etc. are anabolic steroids.
Q19. Hydrocortisone differ from cortisone in possessing -
At the C-11 position cortisone has C>=O group and hydrocortisone has >-OH group
Q20. Sulphonamides act as antibacterial drug due to -
The free amino group in sulphonamides is responsible for their abtibacterial action.
Q21. The structure of penicillin consists of
Penicillin consists of thiazolidine and β - lactam ring.
Q22. Which one if these antibiotics is effective in the treatment of intestinal amoebiasis?
Paromomycin is an aminoglycosides antibiotic, used to treat intestinal amoebiasis infections.
Q23. Vermox is a common brand for -
Vermox is the brand name for mebendazole which is anti-worm (anthelmintic) drug.
Q24. Which one of these drugs is used as an opthalmic diagnostic agent?
Fluoresceine is orange red, non toxic and acidic dye of xanthene series. It is used as opthalmic diagnostic agents.
Q25. Evans blue is used to determine -
Evans blue is an azo dye which has very high affinity for serum albumin. Because of thus it is used to determine blood volume.
Q26. Which one of these vitamin is a naphthaquinone derivative?
Vitamin K is a group of structurally similar fat soluble vitamins having naphthaquinone ring (vitamin K1 and K2)
Q27. Chemical structure of halothene is-
Halothane (Fluothane) is an inhalant general anesthatic.chemically it is 2-bromo-2-chloro-1,1,1-trifluoroethane.
Q28. The number of nitrogen atom in benzimidazole is :
2 nitogen atoms are present in one ring (same ring) of benzimidazole.
Q29. which one of these antineoplastic (anticancer) drugs contains platinum?
Cisplatin is diamino-dichloro-platinum, anticancer drug. Now also include carbaplatin, oxaloplatin.
Q30. The organophosphate poisoning is treated by
Pralidoxime is used to treat the poisoning caused by organophosphate and ACH inhibitors.
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