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One Liner

Use of dimecaprol in arsenic poisoning is an example of

Chemical antagonism
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  • A Passive diffusion
  • B Facilitated diffusion
  • C Active transport
  • D Pinocytosis
  • A Dapsone
  • B Meperidine
  • C Phenytoin
  • D Chlorpheniramine
Explanation: N-oxidation is involved in the metabolism of dapsone, meperidine and chloramphenicol. Metabolism of phenytoin involves oxidative Ndealkylation.
  • A CYP378A
  • B CYP4B2
  • C CYP3A4
  • D CYP256
Explanation: CYP3A4 is involved in the metabolism of majority of drugs and is also expressed extrahepatically. In fact, poor bioavailability of many drugs is attributed to the drug metabolism by CYP3A4 in gastrointestinal tract.
  • A Undergoes little first-pass metabolism
  • B Is incompletely absorbed
  • C Is freely water soluble
  • D Is completely absorbed
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