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Multiple Choice Question

_______ is expressed in both the intestinal epithelium and the kidney.

  • A
    CYP378A
  • B
    CYP4B2
  • C
    CYP3A4
  • D
    CYP256
Explanation:
CYP3A4 is involved in the metabolism of majority of drugs and is also expressed extrahepatically. In fact, poor bioavailability of many drugs is attributed to the drug metabolism by CYP3A4 in gastrointestinal tract.
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