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When the effect of one drug is decreased or abolished in the presence of another drug

Drug antagonism
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This question belongs to the set "Revision of Pharmacology, some basic points (one liners)". Click below to read detailed notes and attempt the full quiz.

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Try These Similar MCQs

  • A Heparin & Protamine
  • B Protamine & Zinc
  • C Heparin & Prothrombin
  • D All the above
Explanation: Chemical antagonism does not involve any receptors. Protamine is a positively charged protein at physiological pH and thus antagonizes the effects of Heparin which is negatively charged at physiological pH.
  • A Is more painful
  • B Produces faster response
  • C Is unsuitable for depot preparations
  • D Carries greater risk of anaphylactic reaction
  • A Highly plasma protein bound drugs
  • B Depot preparations
  • C Highly lipid soluble drugs
  • D Poorly lipid soluble drugs
  • A Passive diffusion
  • B Facilitated diffusion
  • C Active transport
  • D Pinocytosis
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