When the effect of one drug is decreased or abolished in the presence of another drug
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One Liner
Antagonist binds with the same receptor as the agonist and inhibits its effect
receptor anatgonism
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The process of absorption, distribution, metabolism and excretion of drugs
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The enhancement of action of one drug by another inactive drug
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The combined effect of two or more drugs is equal to the sum of their indivisual effect
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Chemical name of Aspirin
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Use of dimecaprol in arsenic poisoning is an example of
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binding of Morphine and Naloxone to the Opioid receptors
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When two or more drugs on simultaneous administration show effect greater than that of either drug alone
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Explanation:
CYP3A4 is involved in the metabolism of
majority of drugs and is also expressed
extrahepatically. In fact, poor bioavailability of
many drugs is attributed to the drug metabolism
by CYP3A4 in gastrointestinal tract.
