Quercitrin
Medicinal Chemistry
Molecular Weight
448.38
Molecular Formula
C21H20O11
IUPAC Name
2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-(alpha-L-rhamnopyranosyloxy)-4H-chromen-4-one
Pharmacognosy
Biological Source
Quercus tinctoria, Fagopyrum esculentum
Active Constituents
Quercitrin, Quercetin
Pharmacology & Synthesis
Mechanism of Action
Potent free radical scavenger; inhibits lipid peroxidation.
Pharmacokinetics (ADME)
A: Poorly absorbed intact.
D: Widely distributed after cleavage.
M: Hydrolyzed by gut flora to quercetin.
E: Fecal and renal.
Pharmacodynamics
Reduces capillary fragility, anti-inflammatory, and antiviral properties.
Synthesis Pathway
Biosynthesized via the shikimate and polyketide pathways.
Safety, Warnings & Interactions
Adverse Effects
Mild GI discomfort.
Contraindications
None known.
Drug Interactions
May interact with CYP3A4 substrates.
Pharmaceutics & Compendia
Dosage Forms
Supplements