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A a term applied to the selective synthesis of one diastereomeric form of a compound resulting from the influence of an existing chiral centre adjacent to the developing asymmetric carbon atom.
Pharmaceutical Organic Chemistry Pharmacist Competitive Exams
Q. A a term applied to the selective synthesis of one diastereomeric form of a compound resulting from the influence of an existing chiral centre adjacent to the developing asymmetric carbon atom.
Ans → asymmetric induction
Explanation →
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Q. An agent able to produce positively charged hydrogen ions (H+). [Since the hydrogen ion is a bare proton, it usually exists in a solvated form (such as H3O+).]
Ans → acid
Explanation →
Q. The minimum energy which reacting species must possess in order to be able to form an 'activated complex', or 'transition state', before proceeding to the products.
Ans → activation energy
Explanation →
Q. Reactions in which an unsaturated system is saturated or part saturated by the addition of a molecule across the multiple bond.
Ans → addition reactions
Explanation →
Q. Organic substances occurring naturally, which are basic, forming salts with acids. The basic group is usually an amino function.
Ans → alkaloid
Explanation →
Q. The migration of a double bond in a 3-carbon system from carbon atoms one and two to carbon atoms two and three
Ans → allylic rearrangement
Explanation →
Q. The specific term used to describe carbohydrate stereoisomers differing only in configuration at the hemi-acetal carbon atom.
Ans → anomers
Explanation →
Q. An aromatic molecule or ion possesses aromaticity. Aromaticity is the special property of planar (or nearly planar) cyclic, conjugated systems having (4n+2) conjugated pi electrons.
Ans → aromatic
Explanation →
Q. A term applied to the combination of molecules of a substance with one another to form more complex systems.
Ans → association
Explanation →
Q. A term applied an object or molecule that does not possess symmetry.
Ans → asymmetry
Explanation →
Q. A a term applied to the selective synthesis of one diastereomeric form of a compound resulting from the influence of an existing chiral centre adjacent to the developing asymmetric carbon atom.
Ans → asymmetric induction
Explanation →
Q. The energy levels of electrons in an atom which may be described in terms of the four quantum numbers.
Ans → atomic orbital
Explanation →
Q. The number of particles (atoms or molecules) in one mole of any pure substance.
Ans → Avogadro's constant
Explanation →
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Q. A group that is used to protect a functional group from unwanted reactions. After application the protecting group can be removed to reveal the original functional group.
Ans → protecting group
Explanation →
Q. An agent able to produce positively charged hydrogen ions (H+). [Since the hydrogen ion is a bare proton, it usually exists in a solvated form (such as H3O+).]
Ans → acid
Explanation →
Q. Dosage form comprising several elements (e.g., microspheres or coated pellets) dif- fering in the rate of drug release.
Ans → multi compartment formulation
Explanation →
Q. Name the enzyme associated with hyperuricemia
Ans → PRPP synthetase, HGPRT , Glucose 6-phosphatase
Explanation →
Q. Characteristic angle of slope formed with the horizontal by the side of a static conical mound of powder.
Ans → angle of repose
Explanation →
Q. A very strong attraction between two or more atoms that are sharing their electrons.
Ans → Covalent Bond
Explanation →
Q. When a reaction provides the agents for a subsequent reaction.
Ans → chain reaction
Explanation →
Q. The time it takes for a decaying radioactive substance to be reduced by half.
Ans → half–life
Explanation →
Q. Name the process in which rapid freezing, followed by placement under a vacuum, of a material so that water is lost by sublimation, thereby inhibiting microbial growth
Ans → lyophilization
Explanation →
Q. The deposit of a drug in a body created by injection or by a similar mode of introduction to form a source of slow release.
Ans → depot
Explanation →
Q. A a DNA molecule resulting from the cutting and insertion of DNA from one organism into the DNA of another organism, resulting in a new combination of genetic material
Ans → recombinant DNA molecule
Explanation →
Q. The the sequencing of genomic fragments from microbial communities, allowing researchers to study genes from a collection of multiple species
Ans → metagenomics
Explanation →
Q. Reversal of coagulation or flocculation, i.e., the dispersion of aggregates to form a stable colloidal suspension or emulsion.
Ans → deflocculation
Explanation →
Q. Organic substances occurring naturally, which are basic, forming salts with acids. The basic group is usually an amino function.
Ans → alkaloid
Explanation →
Q. Growth on the skin associated with infection by any of the human papilloma viruses (HPV); commonly known as a wart
Ans → papilloma
Explanation →
Q. Process that differentiates or separates solid particles according to their size using a meshed or perfo- rated device.
Ans → sieving
Explanation →
Q. A group that is used to protect a functional group from unwanted reactions. After application the protecting group can be removed to reveal the original functional group.
Ans → protecting group
Explanation →
Q. Acetyl CoA from the mitochondria is transported into the cytosol after its conversion to
Ans → Citrate
Explanation →
Q. the angle between groups attached on adjacent carbon atoms when viewed in a Newman projection.
Ans → dihedral angle
Explanation →
Q. Name the class of antifungal drugs that inhibit ergosterol biosynthesis
Ans → imidazoles
Explanation →
Q. Lactose intolerance is caused by the deficiency of the enzyme
Ans → Lactase (β-galactosidase)
Explanation →
Q. A thermodynamic quantity which is a measure of the degree of disorder within any system.
Ans → entropy
Explanation →
Q. Used as processing aid in tablet and capsule manufacturing, to facilitate the movement of the formulation into the dye and punch and to reduce the energy of compression.
Ans → lubricant
Explanation →
Q. The copper containing protein involved for the conversion of ferrous iron (Fe2+) to ferric iron (Fe3+) in the plasma
Ans → Ceruloplasmin
Explanation →
Q. The total number of ATP produced by the oxidation of a molecule of palmitic acid is
Ans → 129 ATP,
Explanation →
Q. Existence of two or more different crystal structures for the same compound.
Ans → polymorphism
Explanation →
Q. The electrons of an atom that are highest in energy and in the outermost orbitals.
Ans → Valence Electrons
Explanation →