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Procedure for estimating the concentration or biological activity of a substance by measuring its effect on a living system compared to a standard system
Pharmaceutics Pharmacist Competitive Exams
Q. Procedure for estimating the concentration or biological activity of a substance by measuring its effect on a living system compared to a standard system
Ans → bioassay
Explanation →
This question is taken from the test/quiz post: One liners Pharmaceutics| B.Pharmacy| Pharmacy file-1 - attemp/practice
More oneliners in - One liners Pharmaceutics| B.Pharmacy| Pharmacy file-1
Q. Adherence of particles into a larger mass due to moisture, static charge, or chemical or mechanical binding
Ans → agglomeration
Explanation →
Q. Solid substances that are not crystals. These solids consist of randomly oriented molecules. Solids without definite shape consist of randomly oriented molecules.
Ans → amorphous
Explanation →
Q. Molecules that contain groups with characteristically different properties, e.g., both hydrophilic and lipophilic (hydrophobic) properties.
Ans → amphiphilic
Explanation →
Q. Characteristic angle of slope formed with the horizontal by the side of a static conical mound of powder.
Ans → angle of repose
Explanation →
Q. Process by which food is rendered free from pathogenic, toxigenic, and spoilage organisms.
Ans → appertization
Explanation →
Q. Substance that acts as adhesives to bind together powders for making tablets (direct tableting) or granules (granulation) that are mainly used in tableting.
Ans → binder
Explanation →
Q. Procedure for estimating the concentration or biological activity of a substance by measuring its effect on a living system compared to a standard system
Ans → bioassay
Explanation →
Q. Relative amount of the administered dose of a drug that reaches systemic circulation from a certain dosage form in comparison to the amount that reaches the systemic circulation by iv administration
Ans → bioavailability
Explanation →
Q. Relationship between two preparations of the same drug in the same dosage form that have a similar bioavailability.
Ans → bioequivalence
Explanation →
Q. For a substance, the time required for the amount of a drug or a substance in a biological system to be reduced to one-half of its value by biological processes when the rate of removal is approximately exponential.
Ans → biological half life
Explanation →
Q. Virus, therapeutic serum, toxin, antitoxin, or analogous product applicable to the prevention, treatment, or cure of diseases or injuries in humans and/or animals.
Ans → biological product
Explanation →
Q. A Characteristic of a powder rather than of individual particles given by the mass of powder occupying a known volume
Ans →
Explanation →
More one-liners in - Pharmaceutics
Q. The number of ATP produced when a molecule of acetyl CoA is oxidized through citric acid cycle
Ans → 12
Explanation →
Q. Technique that uses living organisms to make or modify products, to improve plants or animals, or to develop microorganisms for specific uses
Ans → biotechnology
Explanation →
Q. Name the inflammation of the mouth and gums that is often caused by the HSV-1 virus
Ans → herpetic gingivostomatitis
Explanation →
Q. Name the class of exotoxin that targets and lyses red blood cells, as well as other cells
Ans → hemolysin
Explanation →
Q. A a variant of PCR involving the use of fluorescence to allow for the monitoring of the increase in double-stranded template during a PCR reaction as it occurs
Ans → real-time PCR
Explanation →
Q. Used as processing aid in tablet and capsule manufacturing, to facilitate the movement of the formulation into the dye and punch and to reduce the energy of compression.
Ans → lubricant
Explanation →
Q. The following anticoagulant binds with Ca2+ and prevents blood clotting
Ans → Oxalate
Explanation →
Q. The disease characterized by impairment in the absorption of neutral amino acids
Ans → Hartnup’s disease
Explanation →
Q. Cholesterol synthesis is controlled by feedback inhibition of the enzyme
Ans → HMG CoA reductase
Explanation →
Q. The energy needed to remove an electron from a gaseous atom.
Ans → ionization energy
Explanation →
Q. A protein complex in a photosystem, containing a pigment molecule that can undergo oxidation upon excitation by a light-harvesting pigment
Ans → reaction center
Explanation →
Q. Tablet, which does not contain a disintegrant and which is sucked to dissolve in the mouth to produce either a local (e.g., antiseptic) or systemic (e.g., vitamins) effect.
Ans → lozenge
Explanation →
Q. A type of inclusion containing volutin, a polymerized inorganic phosphate that appears red when stained with methylene blue
Ans → metachromatic granule
Explanation →
Q. The glycosidic bonds at the branching points in the structure of starch are
Ans → 1,6- glycosidic bond
Explanation →
Q. Movement of a pathogen from one host to another population through physical contact or through droplet transmission
Ans → horizontal direct transmission
Explanation →
Q. Condition of being aseptic, or statistically free from living microorganisms and their spores.
Ans → sterility
Explanation →
Q. Concentration of a drug that must be achieved in the plasma before any desired therapeutic or pharmacological effect can be obtained.
Ans → minimum effective plasma concentration
Explanation →
Q. The enzyme defect in acute intermittent porphyria
Ans → Uroporphyrinogen synthase I
Explanation →
Q. Name the formula that shows the number and kinds of atoms in a molecule.
Ans → Molecular Formula
Explanation →
Q. Reversible formation of association colloids from surfactants in nonpolar solvents leads to aggregates termed inverted (or inverse, reverse, or reversed) micelles.
Ans → inverted micelle
Explanation →
Q. Visible clumping of red blood cells that can be caused by some viruses, bacteria, and certain diseases in which antibodies
Ans → hemagglutination
Explanation →
Q. Yellowish color of the skin and mucous membranes caused by excessive bilirubin caused by a failure of the liver to effectively process the breakdown of hemoglobin
Ans → jaundice
Explanation →
Q. Trypsin hydrolyses peptide bonds, the carbonyl group of which is contributed by the amino acids
Ans → Arginine and lysine
Explanation →
Q. Process that differentiates or separates solid particles according to their size using a meshed or perfo- rated device.
Ans → sieving
Explanation →
Q. Name the bond that forms between the hydroxyl groups of two sugar molecules
Ans → glycosidic bond
Explanation →
Q. The deposit of a drug in a body created by injection or by a similar mode of introduction to form a source of slow release.
Ans → depot
Explanation →
Q. Existence of two or more different crystal structures for the same compound.
Ans → polymorphism
Explanation →
Q. Destruction or removal of microorganisms in or about an object, e.g., by steam, chemical agents (alcohol, phenol, ethylene oxide gas), high-velocity electron bombardment, gamma or ultraviolet light radiation or filtration.
Ans → sterilization
Explanation →
Q. When the forward and reverse rates are equal in a chemical reaction.
Ans → equilibrium
Explanation →
Q. A solid dosage form prepared to a desired shape, usually in large-scale production, by means of high pressure in a punch and die.
Ans → compressed tablet
Explanation →
Q. When a reaction provides the agents for a subsequent reaction.
Ans → chain reaction
Explanation →