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Procedure for estimating the concentration or biological activity of a substance by measuring its effect on a living system compared to a standard system
Pharmaceutics Pharmacist Competitive Exams
Q. Procedure for estimating the concentration or biological activity of a substance by measuring its effect on a living system compared to a standard system
Ans → bioassay
Explanation →
This question is taken from the test/quiz post: One liners Pharmaceutics| B.Pharmacy| Pharmacy file-1 - attemp/practice
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Q. Adherence of particles into a larger mass due to moisture, static charge, or chemical or mechanical binding
Ans → agglomeration
Explanation →
Q. Solid substances that are not crystals. These solids consist of randomly oriented molecules. Solids without definite shape consist of randomly oriented molecules.
Ans → amorphous
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Q. Molecules that contain groups with characteristically different properties, e.g., both hydrophilic and lipophilic (hydrophobic) properties.
Ans → amphiphilic
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Q. Characteristic angle of slope formed with the horizontal by the side of a static conical mound of powder.
Ans → angle of repose
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Q. Process by which food is rendered free from pathogenic, toxigenic, and spoilage organisms.
Ans → appertization
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Q. Substance that acts as adhesives to bind together powders for making tablets (direct tableting) or granules (granulation) that are mainly used in tableting.
Ans → binder
Explanation →
Q. Procedure for estimating the concentration or biological activity of a substance by measuring its effect on a living system compared to a standard system
Ans → bioassay
Explanation →
Q. Relative amount of the administered dose of a drug that reaches systemic circulation from a certain dosage form in comparison to the amount that reaches the systemic circulation by iv administration
Ans → bioavailability
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Q. Relationship between two preparations of the same drug in the same dosage form that have a similar bioavailability.
Ans → bioequivalence
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Q. For a substance, the time required for the amount of a drug or a substance in a biological system to be reduced to one-half of its value by biological processes when the rate of removal is approximately exponential.
Ans → biological half life
Explanation →
Q. Virus, therapeutic serum, toxin, antitoxin, or analogous product applicable to the prevention, treatment, or cure of diseases or injuries in humans and/or animals.
Ans → biological product
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Q. A Characteristic of a powder rather than of individual particles given by the mass of powder occupying a known volume
Ans →
Explanation →
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Q. Dosage form, semi-solid, used for the administration of drugs via the rectal route, for systemic or local effect.
Ans →
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Q. Process of making dense, spherical pellets by means of special spheronizing or pelletizing equipment.
Ans → spheronization
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Q. When the forward and reverse rates are equal in a chemical reaction.
Ans → equilibrium
Explanation →
Q. Fourth stage of disease, during which the number of pathogens present in the host decreases, along with signs and symptoms of disease
Ans → period of decline
Explanation →
Q. An agent able to produce positively charged hydrogen ions (H+). [Since the hydrogen ion is a bare proton, it usually exists in a solvated form (such as H3O+).]
Ans → acid
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Q. The difference between plasma and serum is the presence or absence of
Ans → Fibrinogen
Explanation →
Q. A solid dosage form prepared to a desired shape, usually in large-scale production, by means of high pressure in a punch and die.
Ans → compressed tablet
Explanation →
Q. Large macromolecules composed of many similar (sometimes identical) smaller molecules, or monomers, linked together.
Ans → Polymers
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Q. A type of strong oxidizing agent that causes free radical formation in cells; can be used as a disinfectant or antiseptic
Ans → peroxygen
Explanation →
Q. Name the structure embedded in the dermis from which hair grows
Ans → hair follicle
Explanation →
Q. A hydrocarbon containing a carbonyl (C=O) adjacent to an ether (C-O-C) linkage.
Ans → Esters
Explanation →
Q. Destruction or removal of microorganisms in or about an object, e.g., by steam, chemical agents (alcohol, phenol, ethylene oxide gas), high-velocity electron bombardment, gamma or ultraviolet light radiation or filtration.
Ans → sterilization
Explanation →
Q. Name the sialic acid, mostly found in the structure of glycoproteins and glycolipids
Ans → N- Acetylneuraminic acid
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Q. A partial agonist is an agonist that produces a maximal response that is less than the maximal response produced by another agonist acting at the same receptors on the same tissue.
Ans → Partial Agonist
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Q. The movement of chemicals (drugs) into, through, and out of biological organisms or their parts.
Ans → Biotranslocation
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Q. Type of comparative bioavailability study designed in such a way as to take into account differences in bioavailability arising from differences between patients suffering from disease
Ans → crossover study
Explanation →
Q. Memberane-body antibody monomer functioning as receptor on the surface of B cells
Ans → IgD
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Q. A group that is used to protect a functional group from unwanted reactions. After application the protecting group can be removed to reveal the original functional group.
Ans → protecting group
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Q. The most important enzyme involved in oxidative deamination is
Ans → Glutamate dehydrogenase
Explanation →
Q. A highly infectious zoonotic disease caused by Coxiella burnetii that farmers can contract from their animals by inhalation
Ans → Q fever
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Q. A negative sign of free energy indicates that the reaction is
Ans → Exergonic or spontaneous
Explanation →
Q. Different crystalline form of a solvated compound that differ in the identity and/or the stoichiometry of the solvating molecule.
Ans → pseudopolymorph
Explanation →
Q. Dosage form in which the active ingredient is insoluble in the carrier; includes aerosols, suspensions, emulsions , and foams
Ans → disperse system
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Q. A conformation in which substituents on two attached saturated carbon atoms overlap when viewed as a Newman projection.
Ans → eclipsed
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Q. Powder formulation in which individual doses of a powdered dosage form are separately wrapped
Ans → divided powder
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Q. The member of the quinolone family that functions by inhibiting the activity of DNA gyrase, blocking DNA replication
Ans → nalidixic acid
Explanation →
Q. An instrument that measures the degree of absorption (or emission) of electromagnetic radiation by a substance.
Ans → spectrophotometer
Explanation →