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Removal of para-nitro group of chloramphenicol may
Pharmacy Pharmacology D. Pharma B. Pharma
Q. 28 of Quiz-66 (Que-ID : 115)
Removal of para-nitro group of chloramphenicol may
- Increases the toxicity
- Decreases bitterness
- Decreses potency
- Increases water solubility
Ans → (c)Decreses potency
Explanation →
This question is taken from this post → Online Practice Test for Pharmacy exams, previous Year questions - attemp/practice
More MCQs in - Online Practice Test for Pharmacy exams, previous Year questions
Q. 1 of Quiz-66 (Que-ID : 88)
Opthalmic solutions are not evaluated for:
- Sterility test
- Active ingredient
- Clarity test
- Pyrogen test
Q. 2 of Quiz-66 (Que-ID : 89)
Which among the given is not suitable for controlled release dosase form
- Diclofenace
- Nicotine
- Carbamazepine
- Fentanyl
Q. 3 of Quiz-66 (Que-ID : 90)
Kries test is related to
- Skin sensitivity studies
- Identification test of resin
- Rancidity index
- Identification test of aloin
Q. 4 of Quiz-66 (Que-ID : 91)
Isoniazid causes hapatotoxicity due to
- Its metabolite acetylhydrazine
- Accumulation of isoniazid in hepatic cells
- Its metabolite acetylisoniazid
- Deficience of pyrifoxine caused by prolonged isoniazid theory
Q. 5 of Quiz-66 (Que-ID : 92)
Which one of the following drug's tablet should be stored in the closely tight container to prevent loss of potency?
- Phenytoin
- Propranolol
- Nitroglycerine
- All of these
Q. 6 of Quiz-66 (Que-ID : 93)
Metabolite of chlordiazepoxide is
- Nordiazepam
- Oxazepam
- Demoxipam
- All of these
Q. 7 of Quiz-66 (Que-ID : 94)
Lemon Grass oil is obtained by steam distilation of the
- Fresh leaves of Eucalyptus globulus
- Fresh flowering tops of the menths piperata
- Leaves of aerial parts of the cymopogon citratus
- Pericarp of the ripe or nearly ripe fruits of citrus limonis
Q. 8 of Quiz-66 (Que-ID : 95)
Azaspirodecandione agents are primarily used in the treatment of
- Obsessive-compulsive disorders
- Schizophrenia
- Anxiety
- Mania
Q. 9 of Quiz-66 (Que-ID : 96)
Praracetamol is a derivative of:
- p-amino phenol
- Aryl acetic acid
- Aryl propionic acid
- Anthranilic acid
Q. 10 of Quiz-66 (Que-ID : 97)
Efficiency of ball mill depends on
- Rotational speed
- Density of balls
- Volume occupied by the balls
- All of these
Q. 11 of Quiz-66 (Que-ID : 98)
Which of the following properties of a drug is affected by micronisation
- Flow properties
- Chemical stability
- Therapeutic effectiveness
- All of these
Q. 12 of Quiz-66 (Que-ID : 99)
The phosphate antiviral agent is
- Ribavirin
- Didanosine
- Ganciclovir
- Foscarnet
Q. 13 of Quiz-66 (Que-ID : 100)
side effect of drugs is arise due to its intraction to cellular molucules other than the target. these effect can be minimized by their:
- specificity
- Solubility
- Affinity
- Hydrophobicity
Q. 14 of Quiz-66 (Que-ID : 101)
Which statement is not correct about levodopa?
- In perkinsonism, phenothiazines reduce its efficacy
- It is a prodrug
- Pyridoxine reduces effect of levodopa in parkinsonism.
- Domperidone blocks levodopa induced emesis and its therapeutic potential
Q. 15 of Quiz-66 (Que-ID : 102)
Most widely used film former in nail lacquer is
- Ethyle cellulose
- cellulose acetate
- cellulose nitrate
- cellulose acetobutyrate
Q. 16 of Quiz-66 (Que-ID : 103)
Which of the following metabolite of cyclophosphamide is responsible for its anti-tumor actitivity?
- Phosphoramide mustard
- Acrolein
- Aldophosphamide
- 4-hydroxy cyclophosphamide
Q. 18 of Quiz-66 (Que-ID : 105)
Food poisoning is caused by :
- Clostridium tetani
- Clostridium welchi
- Clostridium botulinium
- Clostridium septicum
Q. 19 of Quiz-66 (Que-ID : 106)
Which animal is used for studying insulin preparations?
- Horse
- Pigeon
- Rabbit
- Chicken
Q. 20 of Quiz-66 (Que-ID : 107)
Geiger muller counter is used in :
- UV specroscopy
- Ionisation methods
- IR spectroscopy
- NMR spectroscopy
Q. 21 of Quiz-66 (Que-ID : 108)
Antipsychotic drug-induced parkinsonism is treated by
- Trihexyphenidyl
- Levodopa
- Selegiline
- Amantadine
Q. 22 of Quiz-66 (Que-ID : 109)
As per drug and cosmetic act 1940 phenobarbitone sodium belongs to
- Schedule L
- Shedule X
- Shedule R
- Shedule O
Q. 23 of Quiz-66 (Que-ID : 110)
Menthol is the main constituent of the volatile oil of
- Pinus leaf
- Peppermint leaf
- Clove buds
- Rose marry
Q. 24 of Quiz-66 (Que-ID : 111)
The nitrogen in ephedrine is present as a
- Primary amine
- Secondary amines
- Tertiary amines
- Quarternary amines
Q. 26 of Quiz-66 (Que-ID : 113)
Sterilisation of packed food such as milk and meat products can be done by
- Gas
- Moist heat
- Radiation
- Dry heat
Q. 27 of Quiz-66 (Que-ID : 114)
Chlorophyll test is positive in
- Male fern
- Clove
- Rhubarb
- Pale catechu
Q. 28 of Quiz-66 (Que-ID : 115)
Removal of para-nitro group of chloramphenicol may
- Increases the toxicity
- Decreases bitterness
- Decreses potency
- Increases water solubility
Q. 29 of Quiz-66 (Que-ID : 116)
A process of sepration of molecules through the use of semi-permeable membrane is known as
- Osmosis
- Dialysis
- Seiving
- Diffusion
Q. 30 of Quiz-66 (Que-ID : 117)
Which one of the following is the initial step in the absorption of the drug from a tablet
- Deaggregation
- Diffusion
- Disintegration
- Dissolutuin
Q. 32 of Quiz-66 (Que-ID : 119)
The female insect Coccus cacti is the source of
- Honey
- Canthrites
- Shellac
- Colchicine
Q. 33 of Quiz-66 (Que-ID : 120)
Tragacanth in water is associated with
- Plastic flow
- Pseudoplatic flow
- Dialatant flow
- None of these
Q. 34 of Quiz-66 (Que-ID : 121)
Antioxidants are added in lipstics to
- Impart pleasant ordour
- Staining of lips
- Dissolving insoluble Pigments and dyes
- Prevent rancidity
Q. 35 of Quiz-66 (Que-ID : 122)
Borntrager test is used to identification of
- Senna
- Squill
- Cinchona
- Digitalis
Q. 36 of Quiz-66 (Que-ID : 123)
Plasma protiens act as
- Reserve protiens
- Immunoglobulins
- Buffers
- All of these
Q. 37 of Quiz-66 (Que-ID : 124)
Ketone bodies are synthesised from the fatty acid oxidisation products by which of the following organ
- Brain
- Liver
- Skeletal muscle
- Kidney
Q. 38 of Quiz-66 (Que-ID : 125)
An example of protien denaturation is
- Dissolving sugar in water
- Metabolism of meat
- Heating milk
- Heating egg
Q. 39 of Quiz-66 (Que-ID : 126)
An enzyme catalysed the conversion of alddose sugar to ketose sugar would be classified as
- Isomerases
- Transferases
- Hydrolysases
- Oxydoreductases
Q. 40 of Quiz-66 (Que-ID : 127)
The constituent of essential oil is
- Polyterpenoid
- Tetraterpenoid
- mono and sesquiterpenoid
- Triterpenoid
Q. 41 of Quiz-66 (Que-ID : 128)
Which of the given combination has an intraction, beneficial for routine clinical use?
- Hydralazine and atenolol
- Metochlopramide and levodopa
- Quinidine and digoxine
- Furosemide and lithium carbonate
Q. 42 of Quiz-66 (Que-ID : 129)
Hyperuricemia is associated with the the abnormal metabolism of
- Purine
- Thiamine
- Riboflavin
- Pyrimidine
Q. 43 of Quiz-66 (Que-ID : 130)
Active immunity is induced by
- Placental transfer of antibodies
- Infection
- Injection of gamma-globulins
- Injection of antibodies
Q. 44 of Quiz-66 (Que-ID : 131)
HIV infection can be clinical controlled with
- Ribavirin
- Ganciclovir
- Stavudine
- Acyclovir
Q. 45 of Quiz-66 (Que-ID : 132)
An anti-arrythmic drug that is also used to control seizures is
- Lidocain
- Disipyramide
- Phenytoin
- Amiodarone
Q. 46 of Quiz-66 (Que-ID : 133)
Drug of choice for thyroid storm is
- Carbimazole
- Radioactive iodine
- Propyl thiouracil
- Centimizone
Q. 47 of Quiz-66 (Que-ID : 134)
The cellular organells called 'suiside bags' are
- Lysosomes
- Nucleolus
- Ribosomes
- Golgi's bodies
Q. 48 of Quiz-66 (Que-ID : 135)
The drug included in 'dope test' for athletes is
- Propranolol
- Prazocine
- Dexamphetamine
- Diazepam
Q. 50 of Quiz-66 (Que-ID : 137)
List of minimum equipements required for efficient running of pharmacy is given in shedule
- M
- N
- A
- R
More MCQs In - Pharmacy Pharmacology D. Pharma B. Pharma
Q. 15 of Quiz- (Que-ID : 658)
Pyridoxine is administered with isoniazid to minimise the:
- Hepatotoxicity
- Neurotoxicity
- Nephrotoxicity
- Allergic reaction
Q. 16 of Quiz- (Que-ID : 193)
Drug of choice in acute attack of migraine is:
- Methylsergide
- Ergotamine
- Serotonin
- Nicotine
Q. 20 of Quiz- (Que-ID : 663)
Sodium valproate prevent the epileptic seizure by -
- Depressing the CNS
- Preventing influx of sodium
- Preventing influx of calcium
- None of the above
Q. 13 of Quiz- (Que-ID : 656)
Tetracycline act by -
- Inhibition of protein synthesis
- Interfering in cell wall synthesis
- Altering the permeability of cell membrane of organism
- All of the above
Q. 4 of Quiz- (Que-ID : 1581)
Amino acids with carbon chains that can be metabolically converted into glucose or glycogen are called… .
- Metagenic amino acids
- Glucogenic amino acids
- Ketogenic amino acids
- Glutamic amino acids
Q. 21 of Quiz- (Que-ID : 1330)
Which of these data of marketing research is more reliable?
- Primary data
- secondary data
- both primary and secondary data
- none of the above
Q. 3 of Quiz- (Que-ID : 1263)
Abnormal constituent in jaundice is-
- Sugar
- Protein
- Bilirubin
- Ketone bodies
Q. 6 of Quiz- (Que-ID : 16)
Which one of these is non barbiturate, used for paediatric anaesthesia?
- Nikethamide
- Morphine
- Ketamine
- None of these
Q. 10 of Quiz- (Que-ID : 1527)
A study dealing with the explanations of how an organ works would be an example of _____
- anatomy
- physiology
- cytology
- teleology
Q. 30 of Quiz- (Que-ID : 1290)
Allopurinol when administered with mercaptopurine, increases the action of mercaptopurine by-
- Inhibiting the enzyme - Xanthine oxidase
- decreasing its absorption
- displacing from proteine binding site
- none of these
Q. 19 of Quiz- (Que-ID : 1369)
In TCA, oxaloacetate is formed from-
- Fumarate
- L-ketoglutarate
- succinate
- Malate
Q. 10 of Quiz- (Que-ID : 1270)
Rheumatoid arthritis is a chronic disease manifested primarily by-
- Thickening of arterial walls
- Inflammation
- Imbalance of oxygen
- Rise of BP
Q. 8 of Quiz- (Que-ID : 18)
Salicylate decreases the synthesis of one of the following
- Bradykinin
- Histamine
- Prostaglandin
- None of these
Q. 12 of Quiz- (Que-ID : 463)
The citrate is converted into isocitrate via cis-aconitase by the enzyme:
- Cutrate synthase
- aconitase
- isocitrate dehydrogenate
- malate dehydrogenase
Q. 1 of Quiz- (Que-ID : 1673)
The following are excreted faster in basicurine
- Weak acids
- Strong acids
- Weak Bases
- None of the above
Q. 10 of Quiz- (Que-ID : 1360)
Milky type colour of urine is due to the presence of-
- Albumins
- haemoglobin
- Fatty acid
- Nephritis
Directions :
Q. 3 of Quiz- (Que-ID : 1487)Which of the following drugs is most likely to be absorbed from the stomach
- Hyoscine hydrobromide
- Morphine sulfate
- Diclofenac sodium
- Quinine dihydrochloride
Q. 1 of Quiz- (Que-ID : 411)
Suganril is common brand name for:
- Phenylbutazone
- Piroxican
- Benorylate
- Indomethacin
Q. 3 of Quiz- (Que-ID : 1126)
Which one if these ingredients used in dusting powder, should be sterilised?
- Starch
- Kaolin
- Zinc oxide
- None of the above
Q. 8 of Quiz- (Que-ID : 69)
Which one of these is not a mucolytic?
- Bromhexine
- Ambroxol
- Codiene
- Carbocistein
Q. 5 of Quiz- (Que-ID : 456)
Regular use of isoniazid as antitubercular drug causes deficiency of:
- Vitamin B2
- vitamin B6
- Vitamin B12
- Vitamin B1
Q. 27 of Quiz- (Que-ID : 1705)
The drug commonly used to prevent sepsis in severe burn cases is-
- sulfamethoxazole
- silversulphadiazine
- Salazopyrine
- Sulfadiamidine
Q. 30 of Quiz- (Que-ID : 1123)
The diagnostic agent propyliodone is used for -
- Urography
- Bronchography
- Arteriography
- Myelography
Q. 20 of Quiz- (Que-ID : 3870)
In TCA oxaloacetate is formed from
- Fumarate
- L-ketoglutarate
- Succinate
- Malate
Q. 14 of Quiz- (Que-ID : 631)
Which no. of form should be used for application for grant of license to sell, stock or distribute Drug?
- Form 8
- Form 19
- Form 12 A
- Form 10
Q. 9 of Quiz- (Que-ID : 1613)
EMP stands for …
- Embden Meyerhof & parulekar
- Emmoline Meyerhof & parnas
- Embden Meyerhof & parnas
- Embden Meyerhof & parnar
Q. 13 of Quiz- (Que-ID : 1393)
which one of these is adulterant of digitalis leaves?
- Verbasscum thapsus
- Digitalis lutea
- Digitalis thapsi
- none of the above
Q. 11 of Quiz- (Que-ID : 1840)
Malaria is transmitted through -
- Female culex musquito
- Female housefly
- Female anopheles mosquito
- none of the these
Q. 5 of Quiz- (Que-ID : 1512)
The following disease is worsened by propranolol
- Raynaud’s disease
- Infection
- Heart attack
- Epilepsy
Q. 1 of Quiz- (Que-ID : 411)
Suganril is common brand name for:
- Phenylbutazone
- Piroxican
- Benorylate
- Indomethacin
Q. 1 of Quiz- (Que-ID : 1154)
Type of emulsion produced with bees wax is -
- O/W
- W/O
- Both type
- None of the above
Q. 23 of Quiz- (Que-ID : 3873)
An example of enzyme of oxidoreductase class
- Alcohol dehydrogenase
- Lipase
- Hexokinase
- Aldolase
Q. 8 of Quiz- (Que-ID : 1101)
Which one of these contain benzhydryl group?
- Histamine
- Diphenhydramine
- Dimenhydrinate
- Both option (b) and (c)
Q. 1 of Quiz- (Que-ID : 1642)
Which of the following Antibody involve in Type-I ypersensitivity reaction?
- IgG
- IgA
- IgE
- IgM
Q. 7 of Quiz- (Que-ID : 1473)
Worm infestation is also called ....
- Amoebiasis
- Helminthiasis
- Antiemetics
- None of them
Q. 15 of Quiz- (Que-ID : 3915)
Thiamine includes which one of the following chemical nucleus
- Pyrimidine and thiazole
- Pyrrole and furan
- Imidazole
- Acid phosphatase
Q. 7 of Quiz- (Que-ID : 483)
C-shaped hyaline cartilages are present in
- Larynx
- Trachea
- Pharynx
- None of these
Directions : For each question, choose a correct option from given four options (A, B, C and D)
Q. 3 of Quiz- (Que-ID : 1217)Merk index belongs to the category of-
- Primary source of information
- Secondary source of information
- Tertiary source of information
- none of the above
Q. 24 of Quiz- (Que-ID : 3924)
Main ring present in histidine amino acid is
- Pyrrole
- Imidazole
- Furan
- Thiophene
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