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Which is the non acidic anti-inflammatory agent?

D. Pharma B. Pharma Pharmaceutical Organic Chemistry Bachelor of Pharmacy Diploma in Pharmacy

Q. 12 of Quiz-737 (Que-ID : 1105)

Which is the non acidic anti-inflammatory agent?

  • Oxyphenbutazone
  • Ibuprofen
  • Piroxicam
  • Nabumetone

Ans → (d)Nabumetone

Explanation → Nabumetone is a nonacidic NSAID prodrug that is rapidly metabolized in the liver to the active metabolite, 6-methoxy-2-naphthyl acetic acid. It is available with the brand name nabuflam.

This question is taken from this post → Practice Test #2 | Pharmaceutical Chemistry-II (Organic) - attemp/practice


More MCQs in - Practice Test #2 | Pharmaceutical Chemistry-II (Organic)

Q. 1 of Quiz-737 (Que-ID : 1064)

Commonly used amide type of local anesthetic agent is

  • Procaine
  • Benzocaine
  • Amethocaine
  • Lignocaine

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Q. 2 of Quiz-737 (Que-ID : 1065)

Adrenaline (vasoconstrictor) is used with procaine hydrochloride injection to -

  • Increase the activity of procaine
  • Prolong the duration of anesthetic action
  • Reduce the toxicity
  • None of the above

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Q. 3 of Quiz-737 (Que-ID : 1066)

Mogadone, hypnotic drug is brand name of -

  • Lorazepam
  • Nitrazepam
  • Methaqualone
  • None of the above

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Q. 4 of Quiz-737 (Que-ID : 1097)

which one of these is not true for pilocarpine?

  • It is naturally occuring alkaloid
  • Used for teatment of glaucoma
  • It is a cholinergic antagonist
  • It contains imidazole nucleus

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Q. 5 of Quiz-737 (Que-ID : 1098)

Pseudoephedrine differs from ephedrine in -

  • Chemical structure
  • Isomerism
  • Activity
  • Activity and isomerism

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Q. 6 of Quiz-737 (Que-ID : 1099)

Digoxin contains hydroxyl groups at position-

  • 3 and 12
  • 3 and 14
  • 3, 12 and 14
  • 3, 12 and 15

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Q. 7 of Quiz-737 (Que-ID : 1100)

Lasix is the common brand name for

  • Furosemide
  • Ethacrynic acid
  • Sprinolactone
  • Hydrochlorthiazide

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Q. 8 of Quiz-737 (Que-ID : 1101)

Which one of these contain benzhydryl group?

  • Histamine
  • Diphenhydramine
  • Dimenhydrinate
  • Both option (b) and (c)

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Q. 9 of Quiz-737 (Que-ID : 1102)

The piperidine ring skeleton is present in 

  • Pantazocine
  • Levorphan
  • Pethidine
  • Nalorphine

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Q. 10 of Quiz-737 (Que-ID : 1103)

Paracetamol is marketed as -

  • Tylenol
  • Calpol
  • Crocin
  • All of the above

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Q. 11 of Quiz-737 (Que-ID : 1104)

Which drug has the antiserotonin activity?

  • Cyproheptadine
  • Promethazine
  • Terfinadine
  • All of the above

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Q. 12 of Quiz-737 (Que-ID : 1105)

Which is the non acidic anti-inflammatory agent?

  • Oxyphenbutazone
  • Ibuprofen
  • Piroxicam
  • Nabumetone

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Q. 13 of Quiz-737 (Que-ID : 1106)

Which one of these antitubercular drugs contain pyridine nucleus?

  • Isoniazid
  • Pyrizinamide
  • Ethionamide
  • Cycloserine

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Q. 14 of Quiz-737 (Que-ID : 1107)

Erythromycin will be unstable at pH

  • 8
  • 9
  • 4
  • None of the above

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Q. 15 of Quiz-737 (Que-ID : 1108)

The chemical name for metronidazole is

  • 2-methyl-5- nitro-1H-imidazole-1-ethanol
  • 2-methyl- 5-nitro-1H-imidazole-1-methanol
  • 2-methyl-5-nitro-2H-imidazole-1-ethanol
  • 2-methyl-5-nitro-1H-imidazole-1- methanol

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Q. 16 of Quiz-737 (Que-ID : 1109)

The clofibrate is used in -

  • type iii hyperlipoproteinemia
  • Hypertension
  • vascular problems
  • Raynauds disease

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Q. 17 of Quiz-737 (Que-ID : 1110)

Which of these has azocinyl moiety?

  • Guanethidine
  • Clofibrate
  • Quinidine
  • Quinine

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Q. 18 of Quiz-737 (Que-ID : 1111)

The muscle relaxant 'meprobamate' is a derivative of -

  • Dicarbamate
  • Dioic acid
  • Diamine
  • Diol

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Q. 19 of Quiz-737 (Que-ID : 1112)

Which one of these is not a mydriatic agent?

  • Atropine
  • Homatropine
  • Tropicamide
  • Hyoscyamine

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Q. 20 of Quiz-737 (Que-ID : 1113)

The chemical name 1,1-oxybisethane belongs to -

  • Dimethyl ether
  • Diethyl ether
  • Methyl ethyl ether
  • Cyclopropyl ether

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Q. 21 of Quiz-737 (Que-ID : 1114)

The pentothal sodium is a -

  • Local anesthetic
  • Intravenous anesthetic
  • General anesthetic
  • Hypnotic

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Q. 22 of Quiz-737 (Que-ID : 1115)

The prefix 'sila' is used for

  • Sulphur
  • Silicon
  • Selenium
  • None of the above

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Q. 23 of Quiz-737 (Que-ID : 1116)

Which one of these sulpha drug possess guanidine, used in bacillary dysentery?

  • Sulphadiazine
  • Sulphadimidine
  • Sulphaguanidine
  • Sulphasomidine

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Q. 24 of Quiz-737 (Que-ID : 1117)

The basic ring present in estradiol (female sex hormone) -

  • 5 α - androstane
  • 5 α - estrane
  • 5 α - pregnane
  • None of the above

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Q. 25 of Quiz-737 (Que-ID : 1118)

Two polypeptide chain in insulin is linked together by -

  • Hydrogen bond
  • Disulphide bond
  • Covalent bond
  • None of the above

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Q. 26 of Quiz-737 (Que-ID : 1119)

Acetazolamide, carbonic anhydrase inhibitor, is used in

  • Glaucoma
  • Hypertension
  • Bacterial infection
  • None of the above

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Q. 27 of Quiz-737 (Que-ID : 1120)

One of the anti-rheumatic drug owes its activity due to its sulphide metabolites -

  • Indomethacin
  • Sulindac
  • Ketoprofen
  • None of the above

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Q. 28 of Quiz-737 (Que-ID : 1121)

Which one of these drug is a tricyclic antidepressant drug?

  • Tranylcypromine
  • Phenelzine
  • Isocarboxazide
  • Trimipramine

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Q. 29 of Quiz-737 (Que-ID : 1122)

Aminophylline is salt of ethylenediamine with -

  • Theophylline
  • Caffeine
  • Theobromine
  • None of the above

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Q. 30 of Quiz-737 (Que-ID : 1123)

The diagnostic agent propyliodone is used for -

  • Urography
  • Bronchography
  • Arteriography
  • Myelography

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More MCQs In - D. Pharma B. Pharma Pharmaceutical Organic Chemistry Bachelor of Pharmacy Diploma in Pharmacy

Q. 2 of Quiz- (Que-ID : 1569)

In which of the following bone structures do osteocytes live?

  • canaliculi
  • osteons
  • lacunae
  • lamellae

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Q. 1 of Quiz- (Que-ID : 1310)

The term transactions in business referes to-

  • Exchange of goods
  • goods and services
  • transfer of goods
  • Goods and sale

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Q. 7 of Quiz- (Que-ID : 1554)

Water soluble bases are also known as

  • Greasy ointment bases
  • Greaseless ointment bases
  • Water removable base
  • None of them

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Q. 25 of Quiz- (Que-ID : 1118)

Two polypeptide chain in insulin is linked together by -

  • Hydrogen bond
  • Disulphide bond
  • Covalent bond
  • None of the above

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Q. 29 of Quiz- (Que-ID : 1095)

which one of these antineoplastic (anticancer) drugs contains platinum?

  • Nitrogen mustard
  • Busulphan
  • Cisplatin
  • Daunorubicin

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Q. 4 of Quiz- (Que-ID : 91)

Isoniazid causes hapatotoxicity due to

  • Its metabolite acetylhydrazine
  • Accumulation of isoniazid in hepatic cells
  • Its metabolite acetylisoniazid
  • Deficience of pyrifoxine caused by prolonged isoniazid theory

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Q. 13 of Quiz- (Que-ID : 630)

Schedule F2 of Drug and Cosmetic act is related to - 

  • Standards for opthalmic preparations
  • Standards for surgical dressings
  • Standards for sterilized umbilical tapes
  • Standards for disinfectant fluids

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Q. 9 of Quiz- (Que-ID : 1476)

Substances which anesthetize the restricted area without making subject unconscious…

  • Local anaesthetic
  • Antiemetics
  • General anaesthetic
  • Analgesics

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Q. 19 of Quiz- (Que-ID : 106)

Which animal is used for studying insulin preparations?

  • Horse
  • Pigeon
  • Rabbit
  • Chicken

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Q. 8 of Quiz- (Que-ID : 2210)

Solution of Borax is used as eyewash and wet dressing for wounds is-

  • 1-2% of solution
  • 10-20% of solution
  • 5-10% of solution
  • 70-78% of solution

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Q. 6 of Quiz- (Que-ID : 1835)

In liver, Glucose is stored as-

  • Starch
  • Glycogen
  • Sucrose
  • Lactose

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Q. 23 of Quiz- (Que-ID : 1057)

What is embolism?

  • Breaking of blood clot
  • Stoping of blood clot
  • Movement of blood clot in vessels
  • None of the above

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Q. 1 of Quiz- (Que-ID : 1025)

Containers meant for storage of injectables are made of

  • Lime-soda glass
  • Type II glass
  • Neutral glass
  • Type I and II glass

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Q. 6 of Quiz- (Que-ID : 1627)

Adaptation means reversible change in

  • Functions of cell
  • Size of cell
  • Phenotype of cell
  • All of the above

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Q. 9 of Quiz- (Que-ID : 1102)

The piperidine ring skeleton is present in 

  • Pantazocine
  • Levorphan
  • Pethidine
  • Nalorphine

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Q. 3 of Quiz- (Que-ID : 1560)

The seventh edition of IP was published in …

  • 2011
  • 2012
  • 2013
  • 2014

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Q. 10 of Quiz- (Que-ID : 1076)

Parkinsonism occurs due to -

  • Excess of dopamine
  • Depletion of dopamine
  • Depletion of epinephrine
  • None of the above

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Q. 17 of Quiz- (Que-ID : 1140)

Which fatty base is used in suppositories?

  • Witespol
  • Massupol
  • Cocoa butter
  • Soap glycerin base

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Q. 13 of Quiz- (Que-ID : 1196)

What is a pooled commission?

  • Share of commission on total profit
  • Equal share of commission on total sale
  • Equal share of commission on annual total sale
  • Straight salary plus bonus on sale

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Directions : For each question, choose a correct option from given four options (A, B, C and D)

Q. 29 of Quiz- (Que-ID : 1243)

Number of pharmacists required in a 300 bed hospital?

  • 3
  • 5
  • 8
  • 10

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Q. 6 of Quiz- (Que-ID : 623)

Life period of whole human blood is

  • 21 days
  • 21 months
  • 2 days
  • 30 days

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Q. 15 of Quiz- (Que-ID : 1844)

Which of the following is the carbohydrate of animal origin?

  • Glucose
  • Sucrose
  • starch
  • Glycogen

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Q. 1 of Quiz- (Que-ID : 1067)

Diflunisal is a diflourophenyl derivative of -

  • Acetic acid
  • Propionic acid
  • Salicylic acid
  • Pyrazole

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Q. 28 of Quiz- (Que-ID : 115)

Removal of para-nitro group of chloramphenicol may

  • Increases the toxicity
  • Decreases bitterness
  • Decreses potency
  • Increases water solubility

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Q. 7 of Quiz- (Que-ID : 1501)

The following inhibitor binds only to the ani-onic site of the cholinesterase enzyme

  • Neostigmine
  • Edrophonium
  • Physostigmine
  • Dyflos

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Q. 28 of Quiz- (Que-ID : 1706)

Which of the following is used as cryotherepeutic agent?

  • Calcium carbide
  • Liquid nitrogen
  • calcium cyanamide
  • sodium nitrite

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Q. 3 of Quiz- (Que-ID : 1156)

Moist granules are dried at

  • 50℃
  • 90℃
  • 80℃
  • 60℃

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Directions : For each question, choose a correct option from given four options (A, B, C and D)

Q. 11 of Quiz- (Que-ID : 1225)

Patient with fracture in femure bone is preferably reffered to-

  • Paediatric hospital
  • Maternity hospital
  • Orthopaedic hospital
  • General hospital

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Q. 10 of Quiz- (Que-ID : 653)

Oral anticoagulants act by antagonising the actions of -

  • Calcium ion
  • Prothrombin
  • Vitamin K
  • Fibrinogen

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Q. 16 of Quiz- (Que-ID : 1169)

Dextrose injection is sterilised by

  • Hot air oven
  • Autoclave
  • Tyndallization
  • Pasteurization

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Q. 13 of Quiz- (Que-ID : 3913)

Methionine enkephalin is chain

  • Dipeptide
  • Tripeptide
  • Tetra peptide
  • Pentapeptide

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Q. 26 of Quiz- (Que-ID : 1376)

Pantohenic acid is also known as-

  • vitamin B1
  • vitamin B5
  • vitamin B2
  • Vitamin B12

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Q. 2 of Quiz- (Que-ID : 1036)

Which enzyme does not act on dietary proteins?

  • Elastase
  • Hydrolase
  • Trypsin
  • Chymotrypsin

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Q. 1 of Quiz- (Que-ID : 1528)

Which of the following includes the other terms?

  • systm
  • cell
  • organ
  • tissue

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Q. 6 of Quiz- (Que-ID : 1159)

Which one of these is present in compound sulphur lotion as wetting agent?

  • Talc
  • Quillaia tincture
  • Zinc oxide
  • Sodium citrate

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Q. 11 of Quiz- (Que-ID : 462)

The Enzymes of HMP pathway are located in:

  • Cytosol
  • Adipose tissue
  • Heart
  • Intestine

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Q. 9 of Quiz- (Que-ID : 1162)

Hypodermic injection is given in -

  • Subcutaneous tissue
  • Deltoid muscle
  • Subarachnoid tissue
  • None of the above

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Q. 8 of Quiz- (Que-ID : 1388)

Deadly night shade plant is related to-

  • Hyoscyamus niger
  • Datura stramonium
  • Belladonna
  • none of the above

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Q. 23 of Quiz- (Que-ID : 1176)

Fine droplets of nasal sprays are produced by using -

  • Nebuliser
  • Atomiser
  • Propellent
  • Sprayer

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Q. 2 of Quiz- (Que-ID : 1486)

The majority of drugs cross biological membranes primarily by

  • Passive diffusion
  • Facilitated diffusion
  • Active transport
  • Pinocytosis

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Q. 6 of Quiz- (Que-ID : 1500)

Pilocarpine is used for

  • Glaucoma
  • Paralytic ileus
  • Urinary retention
  • Infection

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Q. 28 of Quiz- (Que-ID : 1706)

Which of the following is used as cryotherepeutic agent?

  • Calcium carbide
  • Liquid nitrogen
  • calcium cyanamide
  • sodium nitrite

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