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Continued substance use despite knowledge of having a persistent or recurrent psychological, or physical problem that is caused or exacerbated by use of the substance

Addiction
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This question belongs to the set "Pharmacology Chapter 1 Revision: Key One-Liner Questions for Pharmacist Exams". Click below to read detailed notes and attempt the full quiz.

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Try These Similar MCQs

  • A Weak acids
  • B Strong acids
  • C Weak Bases
  • D None of the above
Explanation:
because of enhanced disassociation weak acids
are excreted faster in basic (not acidic) urine.
  • A Tolerance
  • B Physical dependence
  • C Psychological dependence
  • D Idiosyncrasy
  • A Increases volume of distribution of the drug
  • B Generally makes the drug long acting
  • C Facilitates glomerular filtration of the drug
  • D Minimises drug interactions
  • A Colon
  • B Gastric fundus
  • C Bladder trigone
  • D Major bronchi
  • A CYP378A
  • B CYP4B2
  • C CYP3A4
  • D CYP256
Explanation: CYP3A4 is involved in the metabolism of majority of drugs and is also expressed extrahepatically. In fact, poor bioavailability of many drugs is attributed to the drug metabolism by CYP3A4 in gastrointestinal tract.
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