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The percent of dose entering the systemic circulation after administration of a given dosage form.

Bioavailability
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This question belongs to the set "Pharmacology Chapter 1 Revision: Key One-Liner Questions for Pharmacist Exams". Click below to read detailed notes and attempt the full quiz.

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  • A Dapsone
  • B Meperidine
  • C Phenytoin
  • D Chlorpheniramine
Explanation: N-oxidation is involved in the metabolism of dapsone, meperidine and chloramphenicol. Metabolism of phenytoin involves oxidative Ndealkylation.
  • A Weak acids
  • B Strong acids
  • C Weak Bases
  • D None of the above
Explanation: because of enhanced disassociation weak acids are excreted faster in basic (not acidic) urine.
  • A It has additional α1 blocking property
  • B It is a selective βS1 blocker
  • C It does not undergo first pass metabolism
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