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One Liner

Death due to cyanide poisoning results from

Inhibition of cytochrome oxidase
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This question belongs to the set "Hospital and Clinical Pharmacy Important Questions (one liners)". Click below to read detailed notes and attempt the full quiz.

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Try These Similar MCQs

  • A Dapsone
  • B Meperidine
  • C Phenytoin
  • D Chlorpheniramine
Explanation: N-oxidation is involved in the metabolism of dapsone, meperidine and chloramphenicol. Metabolism of phenytoin involves oxidative Ndealkylation.
  • A Tolerance
  • B Physical dependence
  • C Psychological dependence
  • D Idiosyncrasy
  • A Increases volume of distribution of the drug
  • B Generally makes the drug long acting
  • C Facilitates glomerular filtration of the drug
  • D Minimises drug interactions
  • A Raynaud’s disease
  • B Infection
  • C Heart attack
  • D Epilepsy
  • A CYP378A
  • B CYP4B2
  • C CYP3A4
  • D CYP256
Explanation: CYP3A4 is involved in the metabolism of majority of drugs and is also expressed extrahepatically. In fact, poor bioavailability of many drugs is attributed to the drug metabolism by CYP3A4 in gastrointestinal tract.
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