d) Anti-metabolic | Methotrexate is used in cancer, autoimmune diseases and ectopic pregnancy.

Pharmacology and Toxicology MCQs | Practice Test #1

Q: Alupent is common brand name for-

b) Phenylephrine | Orciprenaline is also known as metaproterenol, is a bronchodilator.

Q: Which of these hypnotic possess a muscle relaxant property?

d) Diazepam | Diazepam possesses anticonvulasant and skeletal muscle relaxant activity.

Q: Paracetamol is excreted as-

a) Glucuronide | Paracetamol is metabolised in the liver (90-95%) and?excreted?in the urine mainly as the glucuronide and sulphate conjugates. less than 5% is excreted as unchanged paracetamol.

Q: Cardiovuscular action of epinephrine is mediated through-

c) &beta; receptor | Ephinephrine is also known as adrenaline hormone and neurotransmitter. Cardiovascular action of epinephrine is mediated through &amp;beta; receptor.

Q: Slow metabolism of isoniazid in africans are due to-

a) Genetic variation | Isoniazid is given in the treatment of TB. Also known as isonicotinylhydrazine. In Africans Metabolism of Isoniazid is slow due genetic variations.

Q: Phenytoin act as anti-epilectic drug by-

c) acting on cell membrane | Phenytoin is a hydantoin derivative, class 1B anti-arrythmic. It act on cell membrane by sodium channel blockade.

Q: Isosorbide dinitrate is usually administered by-

a) sublingual route | Isosorbide Dinitrate is used to prevent chest pain (angina attacks). It works by relaxing and widening blood vessels so blood can flow more easily to the heart. These tablets will not treat an angina attack that has already begun. They may be also used to control heart failure. generally taken as sublingual route (below the tongue) for quick absorption and action in emergency.

Q: Which one of these antibiotics is used in amoebic dysentery?

c) Paramomycin | Paromomycin is an antimicrobial used to treat a number of parasitic infections including amebiasis, giardiasis, leishmaniasis, and tapeworm infection. It is a first-line treatment for amebiasis or giardiasis during pregnancy. Otherwise it is generally a second line treatment option. It is used by mouth, applied to the skin, or by injection into a muscle.