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Pharmacist Exam MCQs – 50 Important Questions for Quick Revision

✍️ SoloTutes 📅 February 13, 2025688 views 📥 Download PDF
          

This Post contains 50 Important multiple-choice questions (MCQ) designed for quick revision. These questions cover major pharmacy subjects, including Pharmaceutics, Pharmacology, Pharmaceutical Chemistry, Pharmacognosy, and Pharmacy Laws. Each question includes answer choices, the correct option, and a brief explanation to help you grasp key concepts efficiently.

Who Can Use This?
✅ Pharmacy students preparing for D.Pharm, B.Pharm, GPAT, NAPLEX, DHA, HAAD, MOH, and government pharmacist recruitment exams.
✅ Competitive exam aspirants looking for a quick and effective revision tool.
✅ Educators & trainers who want to create pharmacy quizzes or test papers. 
 
        
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Questions

Q1. Which of the following is the prodrug of dopamine?
Levodopa crosses the blood-brain barrier and is converted into dopamine, which helps in Parkinson’s disease.
Q2. Which phase of clinical trials determines the efficacy of a drug?
Phase III trials confirm the drug's effectiveness in large populations before approval.
Q3. Which of the following drugs is an H2 receptor antagonist?
Ranitidine blocks H2 receptors in the stomach, reducing acid production.
Q4. What is the normal pH range of blood?
The normal pH of blood is maintained within 7.35-7.45 for homeostasis.
Q5. Which schedule of the Drugs and Cosmetics Act regulates narcotic drugs in India?
Schedule X drugs require special prescription and strict regulations due to addiction potential.
Q6. Which dosage form is designed for controlled drug release?
Sustained-release tablets release drugs gradually over time, improving compliance.
Q7. What is the primary function of bile salts in digestion?
Bile salts help emulsify fats, making them easier to digest by lipase.
Q8. Which vitamin deficiency causes rickets?
Vitamin D deficiency leads to rickets, causing weak bones in children.
Q9. Which instrument is used for sterilization by dry heat?
Hot air oven sterilizes instruments by dry heat at 160°C for 2 hours.
Q10. Which drug is commonly used in the treatment of tuberculosis?
Rifampicin is part of the first-line treatment for tuberculosis (TB).
Q11. Which polymer is used for enteric coating of tablets?
Eudragit protects tablets from gastric acid and allows release in the intestine.
Q12. Which of the following is a β-lactam antibiotic?
Penicillin contains a β-lactam ring, essential for its antibacterial activity.
Q13. What is the main site of drug metabolism?
The liver is the primary organ for drug metabolism, mainly via CYP enzymes.
Q14. Which neurotransmitter is mainly affected in Alzheimer’s disease?
Alzheimer's disease is associated with a deficiency of acetylcholine.
Q15. Which anticoagulant is used in blood storage bags?
Citrate prevents blood clotting by binding to calcium in storage bags.
Q16. Which of the following is a third-generation cephalosporin?
Ceftriaxone is a third-generation cephalosporin with a broad spectrum.
Q17. Which hormone is responsible for milk ejection?
Oxytocin stimulates milk ejection during breastfeeding.
Q18. What is the normal shelf life of most pharmaceutical tablets?
Most tablets have a shelf life of 3-5 years under proper storage conditions.
Q19. Which drug is used as an antidote for heparin overdose?
Protamine sulfate neutralizes heparin to prevent excessive bleeding.
Q20. Which analytical technique is used for drug purity testing?
HPLC (High-Performance Liquid Chromatography) is widely used for drug purity analysis.
Q21. Which is an example of an aminoglycoside antibiotic?
Amikacin belongs to aminoglycosides, effective against gram-negative bacteria.
Q22. Which dosage form bypasses first-pass metabolism?
Sublingual tablets absorb directly into the bloodstream, avoiding liver metabolism.
Q23. Which of these is a synthetic corticosteroid?
Prednisolone is a synthetic corticosteroid used for inflammation and allergies.
Q24. Which organ is most affected by nephrotoxic drugs?
Nephrotoxic drugs primarily damage the kidneys.
Q25. Which of the following is a macrolide antibiotic?
Erythromycin is a macrolide that inhibits bacterial protein synthesis.
Q26. Which one is a commonly used antiepileptic drug?
Phenytoin is widely used for controlling seizures.
Q27. Which of the following is used as a preservative in pharmaceutical preparations?
Chlorocresol prevents microbial growth in formulations.
Q28. Which gas is used for sterilizing heat-sensitive equipment?
Ethylene oxide gas is used for sterilizing surgical and medical devices.
Q29. What is the use of mannitol in pharmacy?
Mannitol is an osmotic diuretic used to reduce pressure in the brain and eyes.
Q30. Which of the following is a sedative-hypnotic agent?
Diazepam is a benzodiazepine with sedative and hypnotic effects.
Q31. Which is a commonly used emulsifying agent?
Acacia is used to stabilize emulsions in pharmaceutical preparations.
Q32. Which vitamin is synthesized in the skin by sunlight?
Vitamin D is synthesized when the skin is exposed to sunlight.
Q33. Which drug class does Losartan belong to?
Losartan is an angiotensin receptor blocker used for hypertension.
Q34. Which laboratory test evaluates kidney function?
Serum creatinine is a key indicator of kidney function.
Q35. Which schedule deals with prescription drugs in India?
Schedule H drugs are sold only on the prescription of a registered medical practitioner.
Q36. Which organelle is called the 'powerhouse of the cell'?
Mitochondria produce energy through ATP synthesis.
Q37. Which drug is used to treat hyperthyroidism?
Methimazole inhibits thyroid hormone synthesis in hyperthyroidism.
Q38. Which electrolyte is critical for nerve impulse transmission?
Potassium plays a vital role in action potential transmission in nerves.
Q39. Which of the following is a loop diuretic?
Furosemide is a loop diuretic that works in the ascending loop of Henle.
Q40. Which part of the prescription contains instructions to the pharmacist?
Subscription contains directions to the pharmacist about compounding and dispensing.
Q41. What is the role of glidants in tablet formulation?
Glidants like talc improve the flow properties of powders.
Q42. Which test is used to detect the presence of reducing sugars?
Benedict’s test gives a brick-red precipitate in presence of reducing sugars.
Q43. Which Indian body regulates drug approvals?
Central Drugs Standard Control Organization regulates drug approvals in India.
Q44. Which enzyme breaks down proteins in the stomach?
Pepsin is the main proteolytic enzyme in the stomach.
Q45. Which part of the plant is used in case of digitalis?
Leaves of Digitalis purpurea contain cardiac glycosides.
Q46. Which is an example of a fixed-dose combination drug?
Lopinavir/Ritonavir is a combination used in antiretroviral therapy.
Q47. Which type of immunity is passed from mother to child?
Passive natural immunity is passed via placenta and breast milk.
Q48. Which analytical method separates mixtures based on polarity?
Chromatography separates compounds based on their polarity and interaction with the stationary phase.
Q49. Which drug is used for emergency contraception?
Levonorgestrel is a commonly used emergency contraceptive pill.
Q50. Which vitamin is essential for blood clotting?
Vitamin K is crucial for the synthesis of clotting factors.

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