.png){kind=logo}
1 of 60
Q.1 Suganril is common brand name for:
- Phenylbutazone
- Piroxican
- Benorylate
- Indomethacin
Answer ✔ (b) Piroxican
Explanation: Piroxicam is used to relieve the symptoms of rheumatoid and osteoarthritis.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
2 of 60
Q.2 Which one of these is μ-opioid agonist?
- Pethidine
- Codeine
- Nalorphine
- None of these
Answer ✔ (a) Pethidine
Explanation: Pethidine is a phenyl piperidine that is also a strong agonist of μ-opioid receptor.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
3 of 60
Q.3 Levodopa is amino acid precursor of -
- Adrenaline
- Dopamine
- Norepinephrine
- All of these
Answer ✔ (d) All of these
Explanation: levo dopa is the amino acid precursor for dopamine and also for adrenaline and noradrenaline.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
4 of 60
Q.4 The most potent CNS stimulant among xanthine bases are-
- Theophylline
- Caffeine
- Theobromine
- All of these
Answer ✔ (b) Caffeine
Explanation: Caffeine is the most potent CNS stimulant.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
5 of 60
Q.5 Chlorpromazine is useful in the treatment of -
- Mental depression
- Schizophrenia
- Parkinsonism
- None of the above
Answer ✔ (b) Schizophrenia
Explanation: Chlorpromazine (CPZ) is a dopamine antagonist of the typical antipsychotic class of medications possessing additional anti-adrenergic, anti-serotonergic, anti-cholinergic, and anti-histaminergic properties used to treat schizophrenia.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
6 of 60
Q.6 Amlodepine Lowers blood pressure by-
- Inhibition of calcium influx
- Inhibition of angiotensin converting enzyme (ACE)
- Blocking norepinephrine reuptake
- All of the above
Answer ✔ (a) Inhibition of calcium influx
Explanation: Amlodepine is a long acting dihydropyridine type calcium channel blocker.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
7 of 60
Q.7 Cholestyramine is useful in the treatment of -
- Arrhythmia
- Hypertension
- Hyper lipoproteinemia
- Angina pectoris
Answer ✔ (c) Hyper lipoproteinemia
Explanation: Cholestyramine is a bile acid sequestrant.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
8 of 60
Q.8 Clofibrate mainly Lowers the -
- LDL
- VLDL
- HDL
- Chylomicrons
Answer ✔ (b) VLDL
Explanation: Clofibrate is used for controlling cholesterol and triglycerides levels. It changes VLDL to LDL.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
9 of 60
Q.9 Lovastatin is useful in -
- High blood pressure
- Arrhythmia
- Hyper lipoproteinemia
- Angina pectoris
Answer ✔ (c) Hyper lipoproteinemia
Explanation: Lovastatin is a naturally occurring Drug in food, which controls blood cholesterol level.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
10 of 60
Q.10 Oral anticoagulants act by antagonising the actions of -
- Calcium ion
- Prothrombin
- Vitamin K
- Fibrinogen
Answer ✔ (c) Vitamin K
Explanation: vitamin K is a fat soluble vitamin and is required for post translational modification.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
11 of 60
Q.11 Glucocorticoid are used in the treatment of :
- Inflammation
- Inflammation and allergy
- Skin infections
- Allergy
Answer ✔ (b) Inflammation and allergy
Explanation: Glucocorticoids are the part of the feedback mechanism in the immune system that turns immune activity (inflammation).
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
12 of 60
Q.12 The sulphonamides are :
- Bactericidal in nature
- Bacteriostatic in nature
- Bactericidal only at high dose
- None of the above
Answer ✔ (b) Bacteriostatic in nature
Explanation: A Sulphonamide displaces bilirubin. It is competitive inhibitor of enzyme DHPS, cause inhibition of folate synthesis and cause bacteriostatic action.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
13 of 60
Q.13 Tetracycline act by -
- Inhibition of protein synthesis
- Interfering in cell wall synthesis
- Altering the permeability of cell membrane of organism
- All of the above
Answer ✔ (a) Inhibition of protein synthesis
Explanation: Tetracycline is a broad spectrum antibiotic which reduces the growth of bacteria by inhibiting the protein synthesis. it binds with the 30s subunit of microbial ribosomes, to inhibit protein synthesis.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
14 of 60
Q.14 Nystatin is principally effective in:
- Candidia albicans
- Blastomyces
- Cryptococcus histoplasma
- All of the above
Answer ✔ (a) Candidia albicans
Explanation: Nystatin is a polyene antifungal medication derived from streptomyces noursei.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
15 of 60
Q.15 Pyridoxine is administered with isoniazid to minimise the:
- Hepatotoxicity
- Neurotoxicity
- Nephrotoxicity
- Allergic reaction
Answer ✔ (c) Nephrotoxicity
Explanation: Pyridoxine is also called vitamin B6, assist in the balancing of sodium and potassium as well as promoting RBC.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
16 of 60
Q.16 Which one of these combination is used in Chloroquine resistance malaria?
- Trimethoprim + pyrimethamine
- Pyrimethamine + sulphadoxine
- Mefloquine + Primaquine
- None of the above
Answer ✔ (b) Pyrimethamine + sulphadoxine
Explanation: Sulphadoxine + Pyrimethamine (Fansidar) is a combination antimalarial containing the sulphonamide antibiotic sulphadoxine and the anti-protozoal pyrimethamine.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
17 of 60
Q.17 Which one of the enzyme is used in the treatment of cancer?
- L- asparginase
- Phosphodiesterase
- Xanthine Oxidase
- None of the above
Answer ✔ (a) L- asparginase
Explanation: L- asparginase catalyzes the hydrolysis of asparagines to aspartic acid.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
18 of 60
Q.18 Eserine acts by -
- Receptor mechanism
- Acting on cell membrane
- Drug-enzyme interactions
- None of the above
Answer ✔ (c) Drug-enzyme interactions
Explanation: Eserine is another term for physostigmine is a highly toxic parasympathomimetic alkaloid.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
19 of 60
Q.19 Desferrioxamine is a :
- Chelating agent
- Antimetabolite
- Enzyme inhibitor
- None of the above
Answer ✔ (a) Chelating agent
Explanation: Desferrioxamine is a bacterial siderophore produced by the actinobateria, Streptomyces pilosos.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
20 of 60
Q.20 Sodium valproate prevent the epileptic seizure by -
- Depressing the CNS
- Preventing influx of sodium
- Preventing influx of calcium
- None of the above
Answer ✔ (b) Preventing influx of sodium
Explanation: Sodium valproate used in epilepsy, Anorexia, and bipolar disorder.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
21 of 60
Q.21 Which one of these is used with hyoscine to induce Twilight sleep?
- Pentazocine
- Pethidine
- Diphenhydramine
- None of the above
Answer ✔ (b) Pethidine
Explanation: Hyoscine is also known as levo-duboisine, tropane alkaloid.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
22 of 60
Q.22 Ergot preparations are useful in migraine due to its-
- Oxytocic action
- Vasoconstriction action
- α -receptors blocking action
- None of the above
Answer ✔ (b) Vasoconstriction action
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
23 of 60
Q.23 Which one of these is a major tranquilizer?
- Phenelzine
- Promethazine
- Trifluoperazine
- Hydroxyzine
Answer ✔ (c) Trifluoperazine
Explanation: trifluoperazine is a drug from phenothiazine chemical class is atypical antipsychotic drug.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
24 of 60
Q.24 Which one is a cholinomimetic agent?
- Atropine
- Salbutamol
- Tolbutamide
- Acetylcholine
Answer ✔ (d) Acetylcholine
Explanation: Acetylcholine mimics the action of the cholinergic system.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
25 of 60
Q.25 Testosterone is not orally active because?
- React with acid
- Degradation
- Reduction
- Rapid oxidation of 17-hydroxy group to ketones
Answer ✔ (d) Rapid oxidation of 17-hydroxy group to ketones
Explanation: Testosterone is an androgenic steroid hormone, responsible for male characteristics.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
26 of 60
Q.26 Which one of the following drug shows antiplatelet activity?
- Verapamil
- Nifedipine
- Warferin
- Dipyridamole
Answer ✔ (d) Dipyridamole
Explanation: Dipyridamole inhibits Thrombus formation.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
27 of 60
Q.27 Nociceptors are associated with:
- Chemical
- Pain
- Temperature
- Pressure
Answer ✔ (b) Pain
Explanation: A Nociceptor is a receptor of a sensory neuron (nerve cell) that responds to potentially damaging stimuli by sending signals to the spinal cord and brain. This process called nociception usually causes the perception of pain.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
28 of 60
Q.28 Drug that shows selective antagonistic selective H1 antagonistic action?
- Chlorpheniramine
- Cimetidine
- Ranitidine
- Thioperamide
Answer ✔ (a) Chlorpheniramine
Explanation: Chlorpheniramine is a first-generation alkylamine and anti-histamine for H1.
Cimetidine and ranitidine are H2 antagonists and inhibit stomach acid production.
Thioperamide is a selective H3 antagonist, and also capable of crossing the Blood-brain barrier.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
29 of 60
Q.29 Which one is the alkylating anticancer drug?
- Fluorouracil
- Vincristine
- Thiotepa
- Doxorubicin
Answer ✔ (c) Thiotepa
Explanation: Thiotepa is an organophosphorus compound, is an alkylating anticancer drug.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
30 of 60
Q.30 Which one is a HMGC A reductase inhibitor?
- Rhabdomylosis
- Nausea
- Vomiting
- Rise in serum transaminase
Answer ✔ (a) Rhabdomylosis
Explanation: Rhabdomyolysis is a condition in which damaged skeletal muscle tissue breaks down rapidly.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
31 of 60
Q.1 Suganril is common brand name for:
- Phenylbutazone
- Piroxican
- Benorylate
- Indomethacin
Answer ✔ (b) Piroxican
Explanation: Piroxicam is used to relieve the symptoms of rheumatoid and osteoarthritis.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
32 of 60
Q.2 Which one of these is μ-opioid agonist?
- Pethidine
- Codeine
- Nalorphine
- None of these
Answer ✔ (a) Pethidine
Explanation: Pethidine is a phenyl piperidine that is also a strong agonist of μ-opioid receptor.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
33 of 60
Q.3 Levodopa is amino acid precursor of -
- Adrenaline
- Dopamine
- Norepinephrine
- All of these
Answer ✔ (d) All of these
Explanation: levo dopa is the amino acid precursor for dopamine and also for adrenaline and noradrenaline.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
34 of 60
Q.4 The most potent CNS stimulant among xanthine bases are-
- Theophylline
- Caffeine
- Theobromine
- All of these
Answer ✔ (b) Caffeine
Explanation: Caffeine is the most potent CNS stimulant.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
35 of 60
Q.5 Chlorpromazine is useful in the treatment of -
- Mental depression
- Schizophrenia
- Parkinsonism
- None of the above
Answer ✔ (b) Schizophrenia
Explanation: Chlorpromazine (CPZ) is a dopamine antagonist of the typical antipsychotic class of medications possessing additional anti-adrenergic, anti-serotonergic, anti-cholinergic, and anti-histaminergic properties used to treat schizophrenia.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
36 of 60
Q.6 Amlodepine Lowers blood pressure by-
- Inhibition of calcium influx
- Inhibition of angiotensin converting enzyme (ACE)
- Blocking norepinephrine reuptake
- All of the above
Answer ✔ (a) Inhibition of calcium influx
Explanation: Amlodepine is a long acting dihydropyridine type calcium channel blocker.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
37 of 60
Q.7 Cholestyramine is useful in the treatment of -
- Arrhythmia
- Hypertension
- Hyper lipoproteinemia
- Angina pectoris
Answer ✔ (c) Hyper lipoproteinemia
Explanation: Cholestyramine is a bile acid sequestrant.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
38 of 60
Q.8 Clofibrate mainly Lowers the -
- LDL
- VLDL
- HDL
- Chylomicrons
Answer ✔ (b) VLDL
Explanation: Clofibrate is used for controlling cholesterol and triglycerides levels. It changes VLDL to LDL.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
39 of 60
Q.9 Lovastatin is useful in -
- High blood pressure
- Arrhythmia
- Hyper lipoproteinemia
- Angina pectoris
Answer ✔ (c) Hyper lipoproteinemia
Explanation: Lovastatin is a naturally occurring Drug in food, which controls blood cholesterol level.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
40 of 60
Q.10 Oral anticoagulants act by antagonising the actions of -
- Calcium ion
- Prothrombin
- Vitamin K
- Fibrinogen
Answer ✔ (c) Vitamin K
Explanation: vitamin K is a fat soluble vitamin and is required for post translational modification.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
41 of 60
Q.11 Glucocorticoid are used in the treatment of :
- Inflammation
- Inflammation and allergy
- Skin infections
- Allergy
Answer ✔ (b) Inflammation and allergy
Explanation: Glucocorticoids are the part of the feedback mechanism in the immune system that turns immune activity (inflammation).
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
42 of 60
Q.12 The sulphonamides are :
- Bactericidal in nature
- Bacteriostatic in nature
- Bactericidal only at high dose
- None of the above
Answer ✔ (b) Bacteriostatic in nature
Explanation: A Sulphonamide displaces bilirubin. It is competitive inhibitor of enzyme DHPS, cause inhibition of folate synthesis and cause bacteriostatic action.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
43 of 60
Q.13 Tetracycline act by -
- Inhibition of protein synthesis
- Interfering in cell wall synthesis
- Altering the permeability of cell membrane of organism
- All of the above
Answer ✔ (a) Inhibition of protein synthesis
Explanation: Tetracycline is a broad spectrum antibiotic which reduces the growth of bacteria by inhibiting the protein synthesis. it binds with the 30s subunit of microbial ribosomes, to inhibit protein synthesis.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
44 of 60
Q.14 Nystatin is principally effective in:
- Candidia albicans
- Blastomyces
- Cryptococcus histoplasma
- All of the above
Answer ✔ (a) Candidia albicans
Explanation: Nystatin is a polyene antifungal medication derived from streptomyces noursei.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
45 of 60
Q.15 Pyridoxine is administered with isoniazid to minimise the:
- Hepatotoxicity
- Neurotoxicity
- Nephrotoxicity
- Allergic reaction
Answer ✔ (c) Nephrotoxicity
Explanation: Pyridoxine is also called vitamin B6, assist in the balancing of sodium and potassium as well as promoting RBC.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
46 of 60
Q.16 Which one of these combination is used in Chloroquine resistance malaria?
- Trimethoprim + pyrimethamine
- Pyrimethamine + sulphadoxine
- Mefloquine + Primaquine
- None of the above
Answer ✔ (b) Pyrimethamine + sulphadoxine
Explanation: Sulphadoxine + Pyrimethamine (Fansidar) is a combination antimalarial containing the sulphonamide antibiotic sulphadoxine and the anti-protozoal pyrimethamine.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
47 of 60
Q.17 Which one of the enzyme is used in the treatment of cancer?
- L- asparginase
- Phosphodiesterase
- Xanthine Oxidase
- None of the above
Answer ✔ (a) L- asparginase
Explanation: L- asparginase catalyzes the hydrolysis of asparagines to aspartic acid.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
48 of 60
Q.18 Eserine acts by -
- Receptor mechanism
- Acting on cell membrane
- Drug-enzyme interactions
- None of the above
Answer ✔ (c) Drug-enzyme interactions
Explanation: Eserine is another term for physostigmine is a highly toxic parasympathomimetic alkaloid.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
49 of 60
Q.19 Desferrioxamine is a :
- Chelating agent
- Antimetabolite
- Enzyme inhibitor
- None of the above
Answer ✔ (a) Chelating agent
Explanation: Desferrioxamine is a bacterial siderophore produced by the actinobateria, Streptomyces pilosos.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
50 of 60
Q.20 Sodium valproate prevent the epileptic seizure by -
- Depressing the CNS
- Preventing influx of sodium
- Preventing influx of calcium
- None of the above
Answer ✔ (b) Preventing influx of sodium
Explanation: Sodium valproate used in epilepsy, Anorexia, and bipolar disorder.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
51 of 60
Q.21 Which one of these is used with hyoscine to induce Twilight sleep?
- Pentazocine
- Pethidine
- Diphenhydramine
- None of the above
Answer ✔ (b) Pethidine
Explanation: Hyoscine is also known as levo-duboisine, tropane alkaloid.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
52 of 60
Q.22 Ergot preparations are useful in migraine due to its-
- Oxytocic action
- Vasoconstriction action
- α -receptors blocking action
- None of the above
Answer ✔ (b) Vasoconstriction action
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
53 of 60
Q.23 Which one of these is a major tranquilizer?
- Phenelzine
- Promethazine
- Trifluoperazine
- Hydroxyzine
Answer ✔ (c) Trifluoperazine
Explanation: trifluoperazine is a drug from phenothiazine chemical class is atypical antipsychotic drug.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
54 of 60
Q.24 Which one is a cholinomimetic agent?
- Atropine
- Salbutamol
- Tolbutamide
- Acetylcholine
Answer ✔ (d) Acetylcholine
Explanation: Acetylcholine mimics the action of the cholinergic system.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
55 of 60
Q.25 Testosterone is not orally active because?
- React with acid
- Degradation
- Reduction
- Rapid oxidation of 17-hydroxy group to ketones
Answer ✔ (d) Rapid oxidation of 17-hydroxy group to ketones
Explanation: Testosterone is an androgenic steroid hormone, responsible for male characteristics.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
56 of 60
Q.26 Which one of the following drug shows antiplatelet activity?
- Verapamil
- Nifedipine
- Warferin
- Dipyridamole
Answer ✔ (d) Dipyridamole
Explanation: Dipyridamole inhibits Thrombus formation.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
57 of 60
Q.27 Nociceptors are associated with:
- Chemical
- Pain
- Temperature
- Pressure
Answer ✔ (b) Pain
Explanation: A Nociceptor is a receptor of a sensory neuron (nerve cell) that responds to potentially damaging stimuli by sending signals to the spinal cord and brain. This process called nociception usually causes the perception of pain.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
58 of 60
Q.28 Drug that shows selective antagonistic selective H1 antagonistic action?
- Chlorpheniramine
- Cimetidine
- Ranitidine
- Thioperamide
Answer ✔ (a) Chlorpheniramine
Explanation: Chlorpheniramine is a first-generation alkylamine and anti-histamine for H1.
Cimetidine and ranitidine are H2 antagonists and inhibit stomach acid production.
Thioperamide is a selective H3 antagonist, and also capable of crossing the Blood-brain barrier.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
59 of 60
Q.29 Which one is the alkylating anticancer drug?
- Fluorouracil
- Vincristine
- Thiotepa
- Doxorubicin
Answer ✔ (c) Thiotepa
Explanation: Thiotepa is an organophosphorus compound, is an alkylating anticancer drug.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
60 of 60
Q.30 Which one is a HMGC A reductase inhibitor?
- Rhabdomylosis
- Nausea
- Vomiting
- Rise in serum transaminase
Answer ✔ (a) Rhabdomylosis
Explanation: Rhabdomyolysis is a condition in which damaged skeletal muscle tissue breaks down rapidly.
Pharmacy • Pharmacology • Biomedical Science • D. Pharma • B. Pharma • General Pharmacology • General Pharmacology
