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The process by which proteins lose their 3-D (tertiary and secondary) structure by application of an external stress, most often heat.
Pharmaceutical Organic Chemistry Pharmacist Competitive Exams
Q. The process by which proteins lose their 3-D (tertiary and secondary) structure by application of an external stress, most often heat.
Ans → Denatured
Explanation →
This question is taken from the test/quiz post: one liner| organic| B.pharmacy| Pharmacy one liners |organic chemistry| B.pharmacy file-5 - attemp/practice
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Q. A bond formed from the electrostatic attraction between ions with different charges. This typically consists of a metal (cation) and a nonmetal (anion). A metal loses electrons to form a cation and some non-metal gains those electrons to form an anion.
Ans → Ionic Bond
Explanation →
Q. It occurs when a hydrogen atom has an electromagnetic attractive interaction with an electronegative atom.
Ans → Hydrogen Bonding
Explanation →
Q. An atom, or group of atoms, that is responsible for reactivity of the molecule it is a part of.
Ans → Functional Groups
Explanation →
Q. A hydrocarbon containing a carbonyl (C=O) adjacent to an ether (C-O-C) linkage.
Ans → Esters
Explanation →
Q. A molecule that seeks out electrons, also known as a Lewis Acid or an electron pair acceptor.
Ans → Electrophile
Explanation →
Q. Electronegativity is a measure of the attraction an atom has for electrons.
Ans → Electronegativity
Explanation →
Q. The process by which proteins lose their 3-D (tertiary and secondary) structure by application of an external stress, most often heat.
Ans → Denatured
Explanation →
Q. A very strong attraction between two or more atoms that are sharing their electrons.
Ans → Covalent Bond
Explanation →
Q. Isomers that differ in the order the atoms are placed. They have the same number of atoms, just in a different order.
Ans → Constitutional Isomers
Explanation →
More one-liners in - Pharmaceutical Organic Chemistry
Q. A a term applied to the selective synthesis of one diastereomeric form of a compound resulting from the influence of an existing chiral centre adjacent to the developing asymmetric carbon atom.
Ans → asymmetric induction
Explanation →
Q. Different crystalline form of a solvated compound that differ in the identity and/or the stoichiometry of the solvating molecule.
Ans → pseudopolymorph
Explanation →
Q. A chemical reaction after which the resulting agents cannot be changed back into the reactions ingredients.
Ans → irreversible reaction
Explanation →
Q. A chemical reaction where water is introduced in another substance usually to separate it.
Ans → hydrolysis
Explanation →
Q. A process in which the forward reaction can reach an equilibrium with the reverse reaction.
Ans → reversible process
Explanation →
Q. The stage of transcription during which RNA polymerase binds to a promoter and transcription begins
Ans → initiation of transcription
Explanation →
Q. reactions which proceed by means of a set of repeating cyclical steps, e.g. the free radical addition of hydrogen bromide to an alkene.
Ans → chain reaction
Explanation →
Q. The total number of ATP produced by the oxidation of a molecule of palmitic acid is
Ans → 129 ATP,
Explanation →
Q. The clones of cell produced by fusing a normal B cell with a myeloma cell that is capable of producing monoclonal antibodies indefinitely
Ans → hybridoma
Explanation →
Q. When particles move to a lower area of concentration from a high area of concentration.
Ans → diffusion
Explanation →
Q. When a compound is changed into water, heat, and CO2 as a result of combining with oxygen.
Ans → combustion
Explanation →
Q. Name the rule that states that atoms will lose, gain, or share electrons in order to achieve a filled valence shell, to complete their octet.
Ans → Octet Rule
Explanation →
Q. The lipids that possess both hydrophobic (non -polar) and hydrophilic (polar) groups are known as
Ans → amphipathic
Explanation →
Q. Solid preparation that on contact with water breaks apart by the effect of gas evolution, resulting commonly from the reaction of hydrogen carbonate with citric or tartaric acid, in order to facilitate dissolution or dispersion of the active ingredient before ingestion.
Ans → effervescent tablet
Explanation →
Q. Method by which powder particles are compressed into a large tablet, called a slug, which is subse- quently dry-screened and compressed into a tablet.
Ans → slugging
Explanation →
Q. The process of separation of a racemate into its two enantiomers by means of some chiral agency.
Ans → resolution
Explanation →
Q. Name the antiviral drugs that block the activity of the HIV integrase responsible for recombination of a DNA copy of the viral genome into the host cell chromosome
Ans → integrase inhibitors
Explanation →
Q. Name the compound that is increased in RBC of anemic patients to facilitate the supply of O2 to the tissues
Ans → 2,3-Bisphosphoglycerate
Explanation →
Q. The isolation of an individual for the purpose of preventing the spread of disease
Ans → quarantine
Explanation →
Q. Name a substance that loses water to form a lower hydrate or becomes anhydrous spontaneously.
Ans → efflorescent
Explanation →
Q. Yellowish color of the skin and mucous membranes caused by excessive bilirubin caused by a failure of the liver to effectively process the breakdown of hemoglobin
Ans → jaundice
Explanation →
Q. Name the organism that grows in the presence of high salt concentration but does not require it
Ans → halotolerant
Explanation →
Q. The compound that facilitates the release of O2 from oxyhemoglobin
Ans → C1– , H+ , 2, 3-BPG
Explanation →
Q. A conformation in which substituents on two attached saturated carbon atoms overlap when viewed as a Newman projection.
Ans → eclipsed
Explanation →
Q. Reversible formation of association colloids from surfactants in nonpolar solvents leads to aggregates termed inverted (or inverse, reverse, or reversed) micelles.
Ans → inverted micelle
Explanation →
Q. An aromatic molecule or ion possesses aromaticity. Aromaticity is the special property of planar (or nearly planar) cyclic, conjugated systems having (4n+2) conjugated pi electrons.
Ans → aromatic
Explanation →
Q. A condition in which a disease caused by or acquired during a medical procedure
Ans → iatrogenic disease
Explanation →
Q. Anti-tuberculosis drug, isonicotinic acid hydrazide (INH) leads to the deficiency of vitamin
Ans → Pyridoxine (B6)
Explanation →
Q. The most important enzyme involved in oxidative deamination is
Ans → Glutamate dehydrogenase
Explanation →