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The process by which proteins lose their 3-D (tertiary and secondary) structure by application of an external stress, most often heat.
Pharmaceutical Organic Chemistry Pharmacist Competitive Exams
Q. The process by which proteins lose their 3-D (tertiary and secondary) structure by application of an external stress, most often heat.
Ans → Denatured
Explanation →
This question is taken from the test/quiz post: one liner| organic| B.pharmacy| Pharmacy one liners |organic chemistry| B.pharmacy file-5 - attemp/practice
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Q. A bond formed from the electrostatic attraction between ions with different charges. This typically consists of a metal (cation) and a nonmetal (anion). A metal loses electrons to form a cation and some non-metal gains those electrons to form an anion.
Ans → Ionic Bond
Explanation →
Q. It occurs when a hydrogen atom has an electromagnetic attractive interaction with an electronegative atom.
Ans → Hydrogen Bonding
Explanation →
Q. An atom, or group of atoms, that is responsible for reactivity of the molecule it is a part of.
Ans → Functional Groups
Explanation →
Q. A hydrocarbon containing a carbonyl (C=O) adjacent to an ether (C-O-C) linkage.
Ans → Esters
Explanation →
Q. A molecule that seeks out electrons, also known as a Lewis Acid or an electron pair acceptor.
Ans → Electrophile
Explanation →
Q. Electronegativity is a measure of the attraction an atom has for electrons.
Ans → Electronegativity
Explanation →
Q. The process by which proteins lose their 3-D (tertiary and secondary) structure by application of an external stress, most often heat.
Ans → Denatured
Explanation →
Q. A very strong attraction between two or more atoms that are sharing their electrons.
Ans → Covalent Bond
Explanation →
Q. Isomers that differ in the order the atoms are placed. They have the same number of atoms, just in a different order.
Ans → Constitutional Isomers
Explanation →
More one-liners in - Pharmaceutical Organic Chemistry
Q. Specific case of drug embedding in insoluble excipients (typically in a polymer) in order to achieve extended release.
Ans → matrix formulation
Explanation →
Q. Isomers that differ in the order the atoms are placed. They have the same number of atoms, just in a different order.
Ans → Constitutional Isomers
Explanation →
Q. The stage of transcription during which RNA polymerase binds to a promoter and transcription begins
Ans → initiation of transcription
Explanation →
Q. A technique that uses a fluorescence microscope and antibody-specific fluorochromes to determine the presence of specific pathogens in a specimen
Ans → immunofluorescence
Explanation →
Q. A term applied to the combination of molecules of a substance with one another to form more complex systems.
Ans → association
Explanation →
Q. FIGLU (formimino glutamic acid) is excreted in urine in the deficiency of vitamin
Ans → Folic acid
Explanation →
Q. An individual capable of transmitting a pathogen to another individual without becoming infected
Ans → passive carrier
Explanation →
Q. Biological molecules, such as DNA and RNA, composed of a nitrogen base, a pentose sugar, and a phosphate group.
Ans → Nucleic Acids
Explanation →
Q. Name the term that refers to a polar molecule or portion of a molecule capable of strong attraction to water molecules
Ans → hydrophilic
Explanation →
Q. Time required for the concentration of a reactant in a given reaction to reach a value that is the arith- metic mean of its initial and final (equilibrium) values.
Ans → half life
Explanation →
Q. An unstable and toxic ions and molecules derived from partial reduction of oxygen
Ans → reactive oxygen species (ROS)
Explanation →
Q. When a substance, called a solvent, is added to a suspension to reduce the concentration.
Ans → dilution
Explanation →
Q. Proteins that participate in ribosome assembly during initiation
Ans → initiation factors
Explanation →
Q. A bond where elections are equally shared between two atoms.
Ans → nonpolar covalent bond
Explanation →
Q. A Formulated preparation of molecules/drugs that are rarely if ever suitable for administration to patients without additives.
Ans → dosage form
Explanation →
Q. A formal non-ambiguous, nomenclature system for the assignment of absolute configuration of structure to chiral atoms, using the Cahn, Ingold and Prelog priority rules.
Ans → R,S convention
Explanation →
Q. Trypsin hydrolyses peptide bonds, the carbonyl group of which is contributed by the amino acids
Ans → Arginine and lysine
Explanation →
Q. Region of the respiratory tract containing the vocal cords; also referred to as the voice box
Ans → larynx
Explanation →
Q. Name the enzyme associated with hyperuricemia
Ans → PRPP synthetase, HGPRT , Glucose 6-phosphatase
Explanation →
Q. Name the term that refers to a nonpolar molecule or portion of a molecule not capable of strong attraction to water molecules
Ans → hydrophobic
Explanation →
Q. A rare form of transmissible spongiform encephalopathy endemic to Papua New Guinea
Ans → kuru
Explanation →
Q. The inhibition of the enzyme pancreatic lipase by bile salts is overcome by a protein, namely
Ans → Colipase
Explanation →
Q. A more negative redox potential represents a greater tendency to lose
Ans → Electrons
Explanation →
Q. The process by which DNA from one organism is cut and new pieces of foreign DNA from a second organism are inserted,
Ans → recombinant DNA technology
Explanation →
Q. An atom, or group of atoms, that is responsible for reactivity of the molecule it is a part of.
Ans → Functional Groups
Explanation →
Q. Enzymes lose the catalytic activity at temperature above 70C due to
Ans → Denaturation
Explanation →
Q. Name the amino acid that directly participates in the synthesis of heme
Ans → Glycine
Explanation →
Q. The process of separation of a racemate into its two enantiomers by means of some chiral agency.
Ans → resolution
Explanation →
Q. A a substance which cannot be further subdivided by chemical methods.
Ans → element
Explanation →
Q. the angle between groups attached on adjacent carbon atoms when viewed in a Newman projection.
Ans → dihedral angle
Explanation →
Q. The representation of a compound by two or more canonical structures in which the valence electrons are rearranged to give structures of similar probability.
Ans → resonance
Explanation →
Q. Name the antibody dimer primarily found in breast milk, mucus, saliva, and tears
Ans → IgA
Explanation →
Q. Name hypothyroidism caused by an autoimmune disease affecting thyroid function
Ans → Hashimoto thyroiditis
Explanation →