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An instrument used to measure the amount of rotation of plane polarized light by a compound, generally prepared in a solution
Pharmaceutical Organic Chemistry Pharmacist Competitive Exams
Q. An instrument used to measure the amount of rotation of plane polarized light by a compound, generally prepared in a solution
Ans → polarimeter
Explanation →
This question is taken from the test/quiz post: one liner| organic| B.pharmacy| Pharmacy one liners |organic chemistry| B.pharmacy file-6 - attemp/practice
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Q. An instrument used to measure the amount of rotation of plane polarized light by a compound, generally prepared in a solution
Ans → polarimeter
Explanation →
Q. A group that is used to protect a functional group from unwanted reactions. After application the protecting group can be removed to reveal the original functional group.
Ans → protecting group
Explanation →
Q. An equimolar mixture of the two enantiomeric isomers of a compound.
Ans → racemic mixture
Explanation →
Q. A a term applied to an atom or molecule having one or more free valencies.
Ans → radical
Explanation →
Q. A chemical processes in which the proportion of more electronegative substituents is decreased, or the charge is made more negative, or the oxidation number is lowered.
Ans → reduction
Explanation →
Q. The process of separation of a racemate into its two enantiomers by means of some chiral agency.
Ans → resolution
Explanation →
Q. The representation of a compound by two or more canonical structures in which the valence electrons are rearranged to give structures of similar probability.
Ans → resonance
Explanation →
Q. A process in which the forward reaction can reach an equilibrium with the reverse reaction.
Ans → reversible process
Explanation →
Q. A formal non-ambiguous, nomenclature system for the assignment of absolute configuration of structure to chiral atoms, using the Cahn, Ingold and Prelog priority rules.
Ans → R,S convention
Explanation →
Q. The term given to organic molecules which contain no multiple bonds.
Ans → saturated
Explanation →
Q. The sideways projection of a carbon-carbon single bond and the attached substituents.
Ans → sawhorse projection
Explanation →
Q. An instrument that measures the degree of absorption (or emission) of electromagnetic radiation by a substance.
Ans → spectrophotometer
Explanation →
More one-liners in - Pharmaceutical Organic Chemistry
Q. The mammalian enzyme with the shortest half-life (about 10 minutes) is
Ans → Ornithine decarboxylase
Explanation →
Q. Substance that acts as adhesives to bind together powders for making tablets (direct tableting) or granules (granulation) that are mainly used in tableting.
Ans → binder
Explanation →
Q. electron systems in which bonding electrons are not localised between two atoms as for a single bond but are spread (delocalized) over the whole group.
Ans → delocalization
Explanation →
Q. Virus, therapeutic serum, toxin, antitoxin, or analogous product applicable to the prevention, treatment, or cure of diseases or injuries in humans and/or animals.
Ans → biological product
Explanation →
Q. the angle between groups attached on adjacent carbon atoms when viewed in a Newman projection.
Ans → dihedral angle
Explanation →
Q. Name the retrovirus responsible for acquired immune deficiency syndrome (AIDS) in humans
Ans → human immunodeficiency virus (HIV)
Explanation →
Q. Name the sialic acid, mostly found in the structure of glycoproteins and glycolipids
Ans → N- Acetylneuraminic acid
Explanation →
Q. A more negative redox potential represents a greater tendency to lose
Ans → Electrons
Explanation →
Q. Use of products containing genetic material (e.g., pDNA, antisense DNA, si RNA) to treat a disease or condition, or to modify or manipulate the expression of genetic material or to alter the biological properties of living cells.
Ans → gene therapy
Explanation →
Q. Name the compound with the greatest standard free energy.
Ans → Phosphoenolpyruvate
Explanation →
Q. Concentration of a drug that must be achieved in the plasma before any desired therapeutic or pharmacological effect can be obtained.
Ans → minimum effective plasma concentration
Explanation →
Q. The inorganic element found in the structure of majority of high-energy compounds
Ans → Phosphorus
Explanation →
Q. Specific case of drug embedding in insoluble excipients (typically in a polymer) in order to achieve extended release.
Ans → matrix formulation
Explanation →
Q. Name the formation, development, and differentiation of blood cells from pluripotent hematopoietic stem cells
Ans → hematopoiesis
Explanation →
Q. Process of making dense, spherical pellets by means of special spheronizing or pelletizing equipment.
Ans → spheronization
Explanation →
Q. An equimolar mixture of the two enantiomeric isomers of a compound.
Ans → racemic mixture
Explanation →
Q. An Obstacle such as coating or embedding, which acts as a factor controlling the rate of drug release.
Ans → diffusion barrier
Explanation →
Q. Different crystalline form of a solvated compound that differ in the identity and/or the stoichiometry of the solvating molecule.
Ans → pseudopolymorph
Explanation →
Q. A chemical reaction where water is introduced in another substance usually to separate it.
Ans → hydrolysis
Explanation →
Q. A partial agonist is an agonist that produces a maximal response that is less than the maximal response produced by another agonist acting at the same receptors on the same tissue.
Ans → Partial Agonist
Explanation →
Q. Name term that describes a solid of regular shape and the presence of three-dimensional order on the level of atomic dimensions, for a given molecule.
Ans → crystalline
Explanation →
Q. A Biologically active substance, which when biodistributed in the body is expected to modify one or more of its functions.
Ans → drug
Explanation →
Q. The number of base pairs present in each turn (pitch) of B-form of DNA helix
Ans → 10
Explanation →
Q. A process in which the forward reaction can reach an equilibrium with the reverse reaction.
Ans → reversible process
Explanation →
Q. The number of particles (atoms or molecules) in one mole of any pure substance.
Ans → Avogadro's constant
Explanation →
Q. Electronegativity is a measure of the attraction an atom has for electrons.
Ans → Electronegativity
Explanation →
Q. Antihelminthic drug of the benzimidazole class that binds to helminthic β-tubulin, preventing microtubule formation
Ans → mebendazole
Explanation →
Q. Name the formula that shows the number and kinds of atoms in a molecule.
Ans → Molecular Formula
Explanation →