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Transition of a suspension of solid, usually colloid, particles in a liquid (sol) to an apparent solid, jelly- like material
Pharmaceutics Pharmacist Competitive Exams
Q. Transition of a suspension of solid, usually colloid, particles in a liquid (sol) to an apparent solid, jelly- like material
Ans → sol-gel transition
Explanation →
This question is taken from the test/quiz post: One liners Pharmaceutics| B.Pharmacy| Pharmacy file-7 - attemp/practice
More oneliners in - One liners Pharmaceutics| B.Pharmacy| Pharmacy file-7
Q. Chemically modified form of a pharmacologically active compound that has to undergo biochemical or chemical transformation before exhibiting its pharmacological effect.
Ans → prodrug
Explanation →
Q. Process that differentiates or separates solid particles according to their size using a meshed or perfo- rated device.
Ans → sieving
Explanation →
Q. Different crystalline form of a solvated compound that differ in the identity and/or the stoichiometry of the solvating molecule.
Ans → pseudopolymorph
Explanation →
Q. Method by which powder particles are compressed into a large tablet, called a slug, which is subse- quently dry-screened and compressed into a tablet.
Ans → slugging
Explanation →
Q. Measure of the fraction of a given drug that is absorbed intact into the systemic circulation from a dosage form, relative to a recognized, clinically proven, standard dosage form of that drug.
Ans → relative bioavailability
Explanation →
Q. Dosage form, semi-solid, used for the administration of drugs via the rectal route, for systemic or local effect.
Ans →
Explanation →
Q. Transition of a suspension of solid, usually colloid, particles in a liquid (sol) to an apparent solid, jelly- like material
Ans → sol-gel transition
Explanation →
Q. Usually small, flat, and soft tablets, which are designed to be placed under the tongue to allow direct absorption of the active ingredient through the mucosa for systemic effect.
Ans → sublingual tablets
Explanation →
Q. Additives making a substance soluble or more soluble, especially in water.
Ans → solubilizing agents
Explanation →
Q. Destruction or removal of microorganisms in or about an object, e.g., by steam, chemical agents (alcohol, phenol, ethylene oxide gas), high-velocity electron bombardment, gamma or ultraviolet light radiation or filtration.
Ans → sterilization
Explanation →
Q. Crystalline form of a compound in which one or more solvent molecules are part of the crystal strucure.
Ans → solvate
Explanation →
Q. Condition of being aseptic, or statistically free from living microorganisms and their spores.
Ans → sterility
Explanation →
Q. Process of making dense, spherical pellets by means of special spheronizing or pelletizing equipment.
Ans → spheronization
Explanation →
More one-liners in - Pharmaceutics
Q. The amino acids required for the synthesis of purines and pyrimidines are
Ans → Glutamine and aspartate
Explanation →
Q. The inhibition of the enzyme pancreatic lipase by bile salts is overcome by a protein, namely
Ans → Colipase
Explanation →
Q. Use of products containing genetic material (e.g., pDNA, antisense DNA, si RNA) to treat a disease or condition, or to modify or manipulate the expression of genetic material or to alter the biological properties of living cells.
Ans → gene therapy
Explanation →
Q. Growth on the skin associated with infection by any of the human papilloma viruses (HPV); commonly known as a wart
Ans → papilloma
Explanation →
Q. Process that occurs when the vapor pressure of the saturated aqueous solution of a substance is less than the vapor pressure of water in the ambient air.
Ans → deliquescence
Explanation →
Q. A group that is used to protect a functional group from unwanted reactions. After application the protecting group can be removed to reveal the original functional group.
Ans → protecting group
Explanation →
Q. Technological process consisting of the application of a substance, which forms a layer e.g, to protect the drug
Ans → coating
Explanation →
Q. Type of comparative bioavailability study designed in such a way as to take into account differences in bioavailability arising from differences between patients suffering from disease
Ans → crossover study
Explanation →
Q. Process that occurs when the vapor pressure of the saturated aqueous solution of a substance is less than the vapor pressure of water in the ambient air.
Ans → deliquescence
Explanation →
Q. Characteristic angle of slope formed with the horizontal by the side of a static conical mound of powder.
Ans → angle of repose
Explanation →
Q. The childrens in the age group between 2-5 years are susceptible to _______ disease.
Ans → Diphtheria
Explanation →
Q. When parts of the nucleus of atoms are forced together to create a new one.
Ans → nuclear fusion
Explanation →
Q. Dosage form in which the active ingredient is insoluble in the carrier; includes aerosols, suspensions, emulsions , and foams
Ans → disperse system
Explanation →
Q. Name a method of acid-fast staining that does not use heat to infuse the primary stain, carbolfuchsin, into acid-fast cells
Ans → Kinyoun technique
Explanation →
Q. The process of separating the lighter particles of a powder from the heavier ones by means of an up- ward-directed stream of fluid (gas or liquid).
Ans → elutriation
Explanation →
Q. Which bond is formed between the negatively charged phosphate groups that holds a lot of potential energy
Ans → high-energy phosphate bond
Explanation →
Q. Crystalline form of a compound in which one or more solvent molecules are part of the crystal strucure.
Ans → solvate
Explanation →
Q. Artificial spherical lipid bilayer droplet formed mainly from phospholipids having a core of water phase, small enough to form a relatively stable dispersion in aqueous media and with potential use in drug delivery.
Ans → liposome
Explanation →
Q. Leukocytes found in the peripheral blood that are characterized by numerous granules
Ans → granulocytes
Explanation →
Q. A functional group consisting of an internal carbonyl group (C=O) bonded to two other carbon atoms
Ans → Ketones
Explanation →
Q. Lowest concentration of an antibacterial drug necessary to inhibit the growth of a microorganism.
Ans → minimum inhibitory concentration (MIC)
Explanation →
Q. When a mix of liquids is separated by heating it up because one liquid boils at a different temperature than the other.
Ans → distillation
Explanation →
Q. Technological process consisting of the application of a substance, which forms a layer e.g, to protect the drug
Ans → coating
Explanation →
Q. Consists of several different layers that are compressed on top of each other, to form a single tablet composed of two or more layers.
Ans → multilayer tablet
Explanation →
Q. Vehicle often ethanol used in combination to increase the solubility of drugs.
Ans → cosolvent
Explanation →
Q. Powder particles, which have been aggregated to form larger irregular particles, usually of 0.5–2 mm diameter.
Ans → granules
Explanation →
Q. A group that is used to protect a functional group from unwanted reactions. After application the protecting group can be removed to reveal the original functional group.
Ans → protecting group
Explanation →
Q. A substance that cannot be divded chemically into component substances.
Ans → element
Explanation →
Q. The isomerism associated with unsaturated fatty acids
Ans → Geometric isomerism (cis-trans isomerism)
Explanation →
Q. Release of a drug from a dosage form that it is not immediate
Ans → modified release
Explanation →