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Home ❭ Questions ❭ One Liners ❭ Dosage form, semi-solid, used for the administration of drugs via the rectal route, for systemic or local effect.
Dosage form, semi-solid, used for the administration of drugs via the rectal route, for systemic or local effect.
Pharmaceutics Pharmacist Competitive Exams
Q. Dosage form, semi-solid, used for the administration of drugs via the rectal route, for systemic or local effect.
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This question is taken from the test/quiz post: One liners Pharmaceutics| B.Pharmacy| Pharmacy file-7 - attemp/practice
More oneliners in - One liners Pharmaceutics| B.Pharmacy| Pharmacy file-7
Q. Chemically modified form of a pharmacologically active compound that has to undergo biochemical or chemical transformation before exhibiting its pharmacological effect.
Ans → prodrug
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Q. Process that differentiates or separates solid particles according to their size using a meshed or perfo- rated device.
Ans → sieving
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Q. Different crystalline form of a solvated compound that differ in the identity and/or the stoichiometry of the solvating molecule.
Ans → pseudopolymorph
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Q. Method by which powder particles are compressed into a large tablet, called a slug, which is subse- quently dry-screened and compressed into a tablet.
Ans → slugging
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Q. Measure of the fraction of a given drug that is absorbed intact into the systemic circulation from a dosage form, relative to a recognized, clinically proven, standard dosage form of that drug.
Ans → relative bioavailability
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Q. Dosage form, semi-solid, used for the administration of drugs via the rectal route, for systemic or local effect.
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Q. Transition of a suspension of solid, usually colloid, particles in a liquid (sol) to an apparent solid, jelly- like material
Ans → sol-gel transition
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Q. Usually small, flat, and soft tablets, which are designed to be placed under the tongue to allow direct absorption of the active ingredient through the mucosa for systemic effect.
Ans → sublingual tablets
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Q. Additives making a substance soluble or more soluble, especially in water.
Ans → solubilizing agents
Explanation →
Q. Destruction or removal of microorganisms in or about an object, e.g., by steam, chemical agents (alcohol, phenol, ethylene oxide gas), high-velocity electron bombardment, gamma or ultraviolet light radiation or filtration.
Ans → sterilization
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Q. Crystalline form of a compound in which one or more solvent molecules are part of the crystal strucure.
Ans → solvate
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Q. Condition of being aseptic, or statistically free from living microorganisms and their spores.
Ans → sterility
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Q. Process of making dense, spherical pellets by means of special spheronizing or pelletizing equipment.
Ans → spheronization
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Q. The movement of chemicals (drugs) into, through, and out of biological organisms or their parts.
Ans → Biotranslocation
Explanation →
Q. A part of the upper throat (pharynx) extending from the posterior nasal cavity; carries air inhaled through the nose
Ans → nasopharynx
Explanation →
Q. Name the stage of transcription during which RNA polymerase binds to a promoter and transcription begins
Ans → initiation of transcription
Explanation →
Q. Dry solid material consisting of many, usually free flowing, fine particles.
Ans → powder
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Q. Pace at which a drug along with the stomach content leaves and enters the duodenum.
Ans → gastric emptying rate
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Q. Name the prokaryotic cell cytoplasmic structures for storing specific nutrients and other resources needed by cells
Ans → inclusions
Explanation →
Q. Name the antiviral drugs that block the activity of the HIV integrase responsible for recombination of a DNA copy of the viral genome into the host cell chromosome
Ans → integrase inhibitors
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Q. Compounds that have the same molecular formula but different structural formulas
Ans → Isomer
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Q. A chemical reaction after which the resulting agents cannot be changed back into the reactions ingredients.
Ans → irreversible reaction
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Q. The vitamin that is regarded as a vitamin in search of a disease
Ans → Vitamin E (tocopherol)
Explanation →
Q. Dosage form, semi-solid, used for the administration of drugs via the rectal route, for systemic or local effect.
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Q. A rare form of transmissible spongiform encephalopathy endemic to Papua New Guinea
Ans → kuru
Explanation →
Q. A substance that can make a chemical reaction faster but which is not actually needed to produce the reaction nor is used in the reaction.
Ans → catalyst
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Q. An antibacterial and antiprotozoan drug of the nitroimidazole class that is activated in anaerobic target cell and introduces DNA strand breakage, thus interfering with DNA replication in target cells
Ans → metronidazole
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Q. A group that is used to protect a functional group from unwanted reactions. After application the protecting group can be removed to reveal the original functional group.
Ans → protecting group
Explanation →
Q. Emulsions in which the dispersed droplets are in the micron-size range.
Ans → microemulsions
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Q. A Substance that absorbs sufficient moisture from the atmosphere to dissolve itself.
Ans → deliquescent
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Q. Lactose intolerance is caused by the deficiency of the enzyme
Ans → Lactase (β-galactosidase)
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Q. Name the types of host cells that a particular virus is able to infect
Ans → host range
Explanation →
Q. Name the class of exotoxin that targets and lyses red blood cells, as well as other cells
Ans → hemolysin
Explanation →
Q. Name the formation, development, and differentiation of blood cells from pluripotent hematopoietic stem cells
Ans → hematopoiesis
Explanation →
Q. Exploratory activity that begins early in pharmaceutics, involving studies designed to determine the compatibility of excipients with the active substance for a biopharmaceutical; physicochemical and bioanalytical investigation
Ans → preformulation
Explanation →
Q. The process by which proteins lose their 3-D (tertiary and secondary) structure by application of an external stress, most often heat.
Ans → Denatured
Explanation →
Q. Small edible package made usually from gelatin or other materials that can be filled with drugs (solids or liquids) to produce a unit dose, mainly for oral use.
Ans → capsule
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Q. Name the compound with the greatest standard free energy.
Ans → Phosphoenolpyruvate
Explanation →
Q. Name a substance that loses water to form a lower hydrate or becomes anhydrous spontaneously.
Ans → efflorescent
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Q. Process of enclosing a drug in a (micro or nano) particle (capsule, liposome, polymer).
Ans → encapsulation
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