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Different crystalline form of a solvated compound that differ in the identity and/or the stoichiometry of the solvating molecule.
Pharmaceutics Pharmacist Competitive Exams
Q. Different crystalline form of a solvated compound that differ in the identity and/or the stoichiometry of the solvating molecule.
Ans → pseudopolymorph
Explanation →
This question is taken from the test/quiz post: One liners Pharmaceutics| B.Pharmacy| Pharmacy file-7 - attemp/practice
More oneliners in - One liners Pharmaceutics| B.Pharmacy| Pharmacy file-7
Q. Chemically modified form of a pharmacologically active compound that has to undergo biochemical or chemical transformation before exhibiting its pharmacological effect.
Ans → prodrug
Explanation →
Q. Process that differentiates or separates solid particles according to their size using a meshed or perfo- rated device.
Ans → sieving
Explanation →
Q. Different crystalline form of a solvated compound that differ in the identity and/or the stoichiometry of the solvating molecule.
Ans → pseudopolymorph
Explanation →
Q. Method by which powder particles are compressed into a large tablet, called a slug, which is subse- quently dry-screened and compressed into a tablet.
Ans → slugging
Explanation →
Q. Measure of the fraction of a given drug that is absorbed intact into the systemic circulation from a dosage form, relative to a recognized, clinically proven, standard dosage form of that drug.
Ans → relative bioavailability
Explanation →
Q. Dosage form, semi-solid, used for the administration of drugs via the rectal route, for systemic or local effect.
Ans →
Explanation →
Q. Transition of a suspension of solid, usually colloid, particles in a liquid (sol) to an apparent solid, jelly- like material
Ans → sol-gel transition
Explanation →
Q. Usually small, flat, and soft tablets, which are designed to be placed under the tongue to allow direct absorption of the active ingredient through the mucosa for systemic effect.
Ans → sublingual tablets
Explanation →
Q. Additives making a substance soluble or more soluble, especially in water.
Ans → solubilizing agents
Explanation →
Q. Destruction or removal of microorganisms in or about an object, e.g., by steam, chemical agents (alcohol, phenol, ethylene oxide gas), high-velocity electron bombardment, gamma or ultraviolet light radiation or filtration.
Ans → sterilization
Explanation →
Q. Crystalline form of a compound in which one or more solvent molecules are part of the crystal strucure.
Ans → solvate
Explanation →
Q. Condition of being aseptic, or statistically free from living microorganisms and their spores.
Ans → sterility
Explanation →
Q. Process of making dense, spherical pellets by means of special spheronizing or pelletizing equipment.
Ans → spheronization
Explanation →
More one-liners in - Pharmaceutics
Q. A Formulated preparation of molecules/drugs that are rarely if ever suitable for administration to patients without additives.
Ans → dosage form
Explanation →
Q. Reactions in which an unsaturated system is saturated or part saturated by the addition of a molecule across the multiple bond.
Ans → addition reactions
Explanation →
Q. The immunoglobulin that can cross the placenta and transfer the mother’s immunity to the developing fetus
Ans → IgG
Explanation →
Q. Transfer of a drug across a membrane by a transporter (often a protein) constituent of the cytosol membrane.
Ans → carrier-mediated drug transport
Explanation →
Q. Artificial spherical lipid bilayer droplet formed mainly from phospholipids having a core of water phase, small enough to form a relatively stable dispersion in aqueous media and with potential use in drug delivery.
Ans → liposome
Explanation →
Q. The network of neurons that connects the CNS with organs, sensory organs, and muscles throughout the body
Ans → peripheral nervous system
Explanation →
Q. Process by which food is rendered free from pathogenic, toxigenic, and spoilage organisms.
Ans → appertization
Explanation →
Q. Additives making a substance soluble or more soluble, especially in water.
Ans → solubilizing agents
Explanation →
Q. Vehicle often ethanol used in combination to increase the solubility of drugs.
Ans → cosolvent
Explanation →
Q. The base pair G-C is more stable and stronger than A-T due to
Ans → 3 Hydrogen bonds
Explanation →
Q. Movement of a pathogen from one host to another population through physical contact or through droplet transmission
Ans → horizontal direct transmission
Explanation →
Q. The immunity produced by injecting a preparation containing ready-made antibodies is called ______.
Ans → Artificial acquired passive immunity
Explanation →
Q. The polymers of monosaccharides or their derivatives, held together by glycosidic bonds
Ans → Polysaccharide
Explanation →
Q. A chemical processes in which the proportion of more electronegative substituents is decreased, or the charge is made more negative, or the oxidation number is lowered.
Ans → reduction
Explanation →
Q. An instrument that measures the degree of absorption (or emission) of electromagnetic radiation by a substance.
Ans → spectrophotometer
Explanation →
Q. Antibody that is a monomer when functioning as a receptor on surface of B cells but a pentamer when secreted in response to specific pathogens;
Ans → IgM
Explanation →
Q. The nucleotide that serves as an intermediate for biosynthetic reaction
Ans → UDP-glucose , CDP- acylglycerol , S Adenosylmethionine
Explanation →
Q. Name a property, which serves as basis for the process whereby surfactants are used for the removal of foreign matter from surfaces (including dirt from clothes or body surfaces).
Ans → detergency
Explanation →
Q. When parts of the nucleus of atoms are forced together to create a new one.
Ans → nuclear fusion
Explanation →
Q. An equimolar mixture of the two enantiomeric isomers of a compound.
Ans → racemic mixture
Explanation →
Q. The relation between the change of free energy (G), enthalpy (H) and entropy (S) is expressed by the equation
Ans → ΔG = ΔH – TΔS (T = Absolute temperature)
Explanation →
Q. Relationship between two preparations of the same drug in the same dosage form that have a similar bioavailability.
Ans → bioequivalence
Explanation →
Q. Solid substances that are not crystals. These solids consist of randomly oriented molecules. Solids without definite shape consist of randomly oriented molecules.
Ans → amorphous
Explanation →
Q. Small number of cells added to medium to start a culture is commonly called
Ans → inoculum
Explanation →
Q. An instrument used to measure the amount of rotation of plane polarized light by a compound, generally prepared in a solution
Ans → polarimeter
Explanation →
Q. Name the compound that is increased in RBC of anemic patients to facilitate the supply of O2 to the tissues
Ans → 2,3-Bisphosphoglycerate
Explanation →
Q. A a DNA molecule resulting from the cutting and insertion of DNA from one organism into the DNA of another organism, resulting in a new combination of genetic material
Ans → recombinant DNA molecule
Explanation →
Q. Part of the orbital area in an atom where it is impossible to find an electron.
Ans → node
Explanation →
Q. Condition of being aseptic, or statistically free from living microorganisms and their spores.
Ans → sterility
Explanation →