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Different crystalline form of a solvated compound that differ in the identity and/or the stoichiometry of the solvating molecule.
Pharmaceutics Pharmacist Competitive Exams
Q. Different crystalline form of a solvated compound that differ in the identity and/or the stoichiometry of the solvating molecule.
Ans → pseudopolymorph
Explanation →
This question is taken from the test/quiz post: One liners Pharmaceutics| B.Pharmacy| Pharmacy file-7 - attemp/practice
More oneliners in - One liners Pharmaceutics| B.Pharmacy| Pharmacy file-7
Q. Chemically modified form of a pharmacologically active compound that has to undergo biochemical or chemical transformation before exhibiting its pharmacological effect.
Ans → prodrug
Explanation →
Q. Process that differentiates or separates solid particles according to their size using a meshed or perfo- rated device.
Ans → sieving
Explanation →
Q. Different crystalline form of a solvated compound that differ in the identity and/or the stoichiometry of the solvating molecule.
Ans → pseudopolymorph
Explanation →
Q. Method by which powder particles are compressed into a large tablet, called a slug, which is subse- quently dry-screened and compressed into a tablet.
Ans → slugging
Explanation →
Q. Measure of the fraction of a given drug that is absorbed intact into the systemic circulation from a dosage form, relative to a recognized, clinically proven, standard dosage form of that drug.
Ans → relative bioavailability
Explanation →
Q. Dosage form, semi-solid, used for the administration of drugs via the rectal route, for systemic or local effect.
Ans →
Explanation →
Q. Transition of a suspension of solid, usually colloid, particles in a liquid (sol) to an apparent solid, jelly- like material
Ans → sol-gel transition
Explanation →
Q. Usually small, flat, and soft tablets, which are designed to be placed under the tongue to allow direct absorption of the active ingredient through the mucosa for systemic effect.
Ans → sublingual tablets
Explanation →
Q. Additives making a substance soluble or more soluble, especially in water.
Ans → solubilizing agents
Explanation →
Q. Destruction or removal of microorganisms in or about an object, e.g., by steam, chemical agents (alcohol, phenol, ethylene oxide gas), high-velocity electron bombardment, gamma or ultraviolet light radiation or filtration.
Ans → sterilization
Explanation →
Q. Crystalline form of a compound in which one or more solvent molecules are part of the crystal strucure.
Ans → solvate
Explanation →
Q. Condition of being aseptic, or statistically free from living microorganisms and their spores.
Ans → sterility
Explanation →
Q. Process of making dense, spherical pellets by means of special spheronizing or pelletizing equipment.
Ans → spheronization
Explanation →
More one-liners in - Pharmaceutics
Q. Procedure for estimating the concentration or biological activity of a substance by measuring its effect on a living system compared to a standard system
Ans → bioassay
Explanation →
Q. The process of separation of a racemate into its two enantiomers by means of some chiral agency.
Ans → resolution
Explanation →
Q. The majority of bacterial vaccines are stored at a temperature between ___ _____.
Ans → 2 ℃ to 8 ℃
Explanation →
Q. Process in which powder particles are made to aggregate to larger particles called granules.
Ans → granulation
Explanation →
Q. Small sterile usually polymeric matrices, pellets, or particles for insertion or implanting into the body by surgical means or by injection to help achieve sustained release.
Ans → implants
Explanation →
Q. Class of antibacterials that inhibit cell wall synthesis by binding to peptidoglycan subunits and blocking their insertion into the cell wall
Ans → glycopeptides
Explanation →
Q. A a term applied to an atom or molecule having one or more free valencies.
Ans → radical
Explanation →
Q. The disorder in which the patients have an irresistible urge to bite their fingers and lips is
Ans → Lesch-Nyhan syndrome
Explanation →
Q. The determination of the potency of a physical, chemical or biological agent, by means of a biological indicator
Ans → Biological Assay
Explanation →
Q. Process that differentiates or separates solid particles according to their size using a meshed or perfo- rated device.
Ans → sieving
Explanation →
Q. Refers to a polar molecule or portion of a molecule capable of strong attraction to water molecules
Ans → hydrophilic
Explanation →
Q. electron systems in which bonding electrons are not localised between two atoms as for a single bond but are spread (delocalized) over the whole group.
Ans → delocalization
Explanation →
Q. Name a property, which serves as basis for the process whereby surfactants are used for the removal of foreign matter from surfaces (including dirt from clothes or body surfaces).
Ans → detergency
Explanation →
Q. An equimolar mixture of the two enantiomeric isomers of a compound.
Ans → racemic mixture
Explanation →
Q. Used on tablets, granules, pellets, and capsules to make them resistant to gastric fluids but designed to disintegrate, disrupt, or dissolve when the preparation enters the duodenum.
Ans → enteric coating
Explanation →
Q. The regulatory enzyme in the pyrimidine biosynthesis in animals is
Ans → Carbamoyl phosphate synthetase II
Explanation →
Q. Leukocytes found in the peripheral blood that are characterized by numerous granules
Ans → granulocytes
Explanation →
Q. The sideways projection of a carbon-carbon single bond and the attached substituents.
Ans → sawhorse projection
Explanation →
Q. Process of enclosing a drug in a (micro or nano) particle (capsule, liposome, polymer).
Ans → encapsulation
Explanation →
Q. The lipids that possess both hydrophobic (non -polar) and hydrophilic (polar) groups are known as
Ans → amphipathic
Explanation →
Q. Cytokines largely produced by immune system cells that help coordinate efforts against invading pathogens
Ans → interleukins
Explanation →
Q. When particles move to a lower area of concentration from a high area of concentration.
Ans → diffusion
Explanation →
Q. A process in which the forward reaction can reach an equilibrium with the reverse reaction.
Ans → reversible process
Explanation →
Q. A glycoprotein expressed only on the surface of antigen-presenting cells and involved in the presentation of foreign antigens from pathogens ingested by phagocytosis
Ans → MHC II molecule
Explanation →
Q. An aqueous solution used for the prevention and treatment of mouth and throat infections.
Ans → gargle
Explanation →
Q. Close, tight aggregation of colloid particles, emulsion droplets, suspension particles, which are difficult to redisperse.
Ans → coagulation
Explanation →