.png){kind=logo}
Exploratory activity that begins early in pharmaceutics, involving studies designed to determine the compatibility of excipients with the active substance for a biopharmaceutical; physicochemical and bioanalytical investigation
Pharmaceutics Pharmacist Competitive Exams
Q. Exploratory activity that begins early in pharmaceutics, involving studies designed to determine the compatibility of excipients with the active substance for a biopharmaceutical; physicochemical and bioanalytical investigation
Ans → preformulation
Explanation →
This question is taken from the test/quiz post: one liners Pharmaceutics| B.Pharmacy| Pharmacy file-6 - attemp/practice
More oneliners in - one liners Pharmaceutics| B.Pharmacy| Pharmacy file-6
Q. Usually water or low-molecular-weight alcohols or compounds, used in topical applications and in wet granulation, for the production of tablets.
Ans → moistening agents
Explanation →
Q. Dosage form comprising several elements (e.g., microspheres or coated pellets) dif- fering in the rate of drug release.
Ans → multi compartment formulation
Explanation →
Q. Consists of several different layers that are compressed on top of each other, to form a single tablet composed of two or more layers.
Ans → multilayer tablet
Explanation →
Q. Device that disperses liquids to aerosols for therapeutic use by inhalation through a mask.
Ans → nebulizer
Explanation →
Q. Greasy, semi-solid preparation for external application, often anhydrous, containing dissolved or dispersed medicaments.
Ans → ointment
Explanation →
Q. Kinetic model, where the whole body is thought of as a single compartment in which a substance is dis- tributed rapidly, achieving an equilibrium between blood and tissue immediately.
Ans → one-compartment model
Explanation →
Q. Time required to achieve the minimum effective plasma concentration following administration of the dosage form.
Ans → onset of drug action
Explanation →
Q. Process of agglomeration that converts fine powders or granules of bulk drugs and excipients into small, free-flowing, spherical, or semi-spherical units, referred to as pellets.
Ans → pelletization
Explanation →
Q. Science of preparation of drugs, dosage forms, and drug delivery systems taking into account the pharmacokinetics and pharmacodynamics of the drug as well as its physical and chemical properties.
Ans → pharmaceutics
Explanation →
Q. Solid material that exists at least in two different molecular arrangements, i.e., distinctly different crystal species.
Ans → polymorph
Explanation →
Q. Transition of a solid crystalline phase to another phase having the same chemical composition but a dif- ferent crystal structure.
Ans → polymorphic transition
Explanation →
Q. Existence of two or more different crystal structures for the same compound.
Ans → polymorphism
Explanation →
Q. Defined for powders used pharmaceutically, according to particle sizes.
Ans → powder grades
Explanation →
Q. Dry solid material consisting of many, usually free flowing, fine particles.
Ans → powder
Explanation →
More one-liners in - Pharmaceutics
Q. When the forward and reverse rates are equal in a chemical reaction.
Ans → equilibrium
Explanation →
Q. Consists of several different layers that are compressed on top of each other, to form a single tablet composed of two or more layers.
Ans → multilayer tablet
Explanation →
Q. Name the bond that forms between the hydroxyl groups of two sugar molecules
Ans → glycosidic bond
Explanation →
Q. Sweet (often colored) dilute alcohol-based, “hydroalcoholic”, liquid used in the compounding of drugs to be taken by mouth in order to improve palatability.
Ans → elixir
Explanation →
Q. Name the most serious stage of pertussis (whooping cough), characterized by severe and prolonged coughing spells
Ans → paroxysmal stage
Explanation →
Q. A a stain that produces colour around the structure of interest while not coloring the structure itself
Ans → negative stain
Explanation →
Q. A very strong attraction between two or more atoms that are sharing their electrons.
Ans → Covalent Bond
Explanation →
Q. An activated and differentiated B cell that is programmed to respond to secondary exposures to a specific antigen
Ans → memory B cell
Explanation →
Q. A group of common sexually transmitted viruses that may be associated with genital warts or with cervical cancer
Ans → human papillomavirus (HPV)
Explanation →
Q. The Threshold detergent concentration at which micelle formation begins in the bulk phase is called
Ans → critical micelle concentration (cmc)
Explanation →
Q. Name the longest identical peptide chains in antibody molecules (two per antibody monomer) that composed of variable and constant region segments
Ans → heavy chains
Explanation →
Q. Summary of operations carried out to convert a pharmacologically active compound into a dosage form suitable for administration.
Ans → formulation
Explanation →
Q. Small sterile usually polymeric matrices, pellets, or particles for insertion or implanting into the body by surgical means or by injection to help achieve sustained release.
Ans → implants
Explanation →
Q. When a mix of liquids is separated by heating it up because one liquid boils at a different temperature than the other.
Ans → distillation
Explanation →
Q. Reactions in which an unsaturated system is saturated or part saturated by the addition of a molecule across the multiple bond.
Ans → addition reactions
Explanation →
Q. Which is the simplest form of glycolipids which occur in the membranes of nervous tissue.
Ans → Cerebrosides
Explanation →
Q. Type of comparative bioavailability study designed in such a way as to take into account differences in bioavailability arising from differences between patients suffering from disease
Ans → crossover study
Explanation →
Q. The prefix sn used to represent glycerol, sn stands for
Ans → Stereospecific number
Explanation →
Q. The chemical reaction that removes electrons (often as part of H atoms) from donor molecules, leaving them oxidized
Ans → oxidation reaction
Explanation →
Q. Different crystalline form of a solvated compound that differ in the identity and/or the stoichiometry of the solvating molecule.
Ans → pseudopolymorph
Explanation →
Q. The fatty acid that is commonly found in the C2 of triacylglycerols is
Ans → Unsaturated fatty acid
Explanation →
Q. The mammalian enzyme with the shortest half-life (about 10 minutes) is
Ans → Ornithine decarboxylase
Explanation →
Q. Reversal of coagulation or flocculation, i.e., the dispersion of aggregates to form a stable colloidal suspension or emulsion.
Ans → deflocculation
Explanation →
Q. a chemical reaction in which two species (e.g. molecules, ions or radicals) react together to form new chemical species.
Ans → bimolecular reaction
Explanation →