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Powder formulation in which individual doses of a powdered dosage form are separately wrapped
Pharmaceutics Pharmacist Competitive Exams
Q. Powder formulation in which individual doses of a powdered dosage form are separately wrapped
Ans → divided powder
Explanation →
This question is taken from the test/quiz post: one liners Pharmaceutics| B.Pharmacy| Pharmacy file-3 - attemp/practice
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Q. An Obstacle such as coating or embedding, which acts as a factor controlling the rate of drug release.
Ans → diffusion barrier
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Q. Name a stage in the drying of solids, above which the drying rate is linear, at which the drying rate ceases to be linear, until it reaches the equilibrium moisture content.
Ans → critical moisture content
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Q. Formulation in which individual doses of a granulated dosage form are separated
Ans → divided granule
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Q. Type of comparative bioavailability study designed in such a way as to take into account differences in bioavailability arising from differences between patients suffering from disease
Ans → crossover study
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Q. Powder formulation in which individual doses of a powdered dosage form are separately wrapped
Ans → divided powder
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Q. Name term that describes a solid of regular shape and the presence of three-dimensional order on the level of atomic dimensions, for a given molecule.
Ans → crystalline
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Q. A Formulated preparation of molecules/drugs that are rarely if ever suitable for administration to patients without additives.
Ans → dosage form
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Q. Dosage form in which the active ingredient is insoluble in the carrier; includes aerosols, suspensions, emulsions , and foams
Ans → disperse system
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Q. A Biologically active substance, which when biodistributed in the body is expected to modify one or more of its functions.
Ans → drug
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Q. Solid preparation that on contact with water breaks apart by the effect of gas evolution, resulting commonly from the reaction of hydrogen carbonate with citric or tartaric acid, in order to facilitate dissolution or dispersion of the active ingredient before ingestion.
Ans → effervescent tablet
Explanation →
Q. Opposite of deliquescence; the drying of a salt solution when the vapour pressure of water in the saturated solution of a substance is greater than the partial pressure of water in the ambient air.
Ans → efflorescence
Explanation →
Q. Name a technological process, which consists of mixing or inclusion of the therapeutic substance with an excipient or their mixtures, typically as a matrix dosage form, in order to change the rate of release.
Ans → embedding
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Q. Sweet (often colored) dilute alcohol-based, “hydroalcoholic”, liquid used in the compounding of drugs to be taken by mouth in order to improve palatability.
Ans → elixir
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Q. The process of separating the lighter particles of a powder from the heavier ones by means of an upward-directed stream of fluid
Ans → elutriation
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Q. Name a substance that loses water to form a lower hydrate or becomes anhydrous spontaneously.
Ans → efflorescent
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Q. Naturally produced protein synthesis inhibitor of the lincosamide class that binds to the 50S subunit, inhibiting peptide bond formation
Ans → lincomycin
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Q. Examples of two enzymes containing zinc are
Ans → Alcohol dehydrogenase, carbonic anhydrase
Explanation →
Q. The copper containing protein involved for the conversion of ferrous iron (Fe2+) to ferric iron (Fe3+) in the plasma
Ans → Ceruloplasmin
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Q. Different crystalline form of a solvated compound that differ in the identity and/or the stoichiometry of the solvating molecule.
Ans → pseudopolymorph
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Q. Specific case of drug embedding in insoluble excipients (typically in a polymer) in order to achieve extended release.
Ans → matrix formulation
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Q. Concentration of a drug that must be achieved in the plasma before any desired therapeutic or pharmacological effect can be obtained.
Ans → minimum effective plasma concentration
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Q. Characteristic angle of slope formed with the horizontal by the side of a static conical mound of powder.
Ans → angle of repose
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Q. Continued substance use despite knowledge of having a persistent or recurrent psychological, or physical problem that is caused or exacerbated by use of the substance
Ans → Addiction
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Q. Name the adaptive immunity mediated by antibodies produced by B cells
Ans → humoral immunity
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Q. Usually water or low-molecular-weight alcohols or compounds, used in topical applications and in wet granulation, for the production of tablets.
Ans → moistening agents
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Q. Name the molecule that slides between the stacked nitrogenous bases of the DNA double helix, potentially resulting in a frameshift mutation
Ans → intercalating agent
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Q. Ascorbic acid is not synthesized in man due to lack of the enzyme
Ans → L-Gulonolactone oxidase
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Q. Name a method of acid-fast staining that does not use heat to infuse the primary stain, carbolfuchsin, into acid-fast cells
Ans → Kinyoun technique
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Q. The process by which DNA from one organism is cut and new pieces of foreign DNA from a second organism are inserted,
Ans → recombinant DNA technology
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Q. A Solid spherical particles of micron-size range, used as matrix dosage forms.
Ans → microsphere
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Q. An unstable and toxic ions and molecules derived from partial reduction of oxygen
Ans → reactive oxygen species (ROS)
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Q. Sickling of RBC in sickle-cell anemia is due to polymerization of
Ans → Deoxyhemoglobin,
Explanation →
Q. A substance that can make a chemical reaction faster but which is not actually needed to produce the reaction nor is used in the reaction.
Ans → catalyst
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Q. The inhibition of the enzyme pancreatic lipase by bile salts is overcome by a protein, namely
Ans → Colipase
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Q. Name the compound that is increased in RBC of anemic patients to facilitate the supply of O2 to the tissues
Ans → 2,3-Bisphosphoglycerate
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Q. A hydrocarbon containing a carbonyl (C=O) adjacent to an ether (C-O-C) linkage.
Ans → Esters
Explanation →
Q. The deposit of a drug in a body created by injection or by a similar mode of introduction to form a source of slow release.
Ans → depot
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Q. Transfer of a drug across a membrane by a transporter (often a protein) constituent of the cytosol membrane.
Ans → carrier-mediated drug transport
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Q. DNA-binding proteins found in eukaryotes and archaea that aid in orderly packaging of chromosomal DNA
Ans → histones
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Q. The disorders characterized by decreased synthesis or total absence of globin chains of hemoglobin are collectively known as
Ans → Thalassemias
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Q. Name the formation, development, and differentiation of blood cells from pluripotent hematopoietic stem cells
Ans → hematopoiesis
Explanation →
Q. Name the rule that states that atoms will lose, gain, or share electrons in order to achieve a filled valence shell, to complete their octet.
Ans → Octet Rule
Explanation →
Q. A form of microbial control using heat that is applied to foods; kills pathogens and reduces the number of spoilage-causing microbes while maintaining food quality
Ans → pasteurization
Explanation →
Q. Dosage form, semi-solid, used for the administration of drugs via the rectal route, for systemic or local effect.
Ans →
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Q. A virus composed of a nucleic acid core, either DNA or RNA, surrounded by a capsid
Ans → naked virus
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Q. Existence of two or more different crystal structures for the same compound.
Ans → polymorphism
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Q. Name a differential staining technique that distinguishes bacteria based upon their cell wall structure
Ans → Gram stain procedure
Explanation →
Q. The percent of dose entering the systemic circulation after administration of a given dosage form.
Ans → Bioavailability
Explanation →