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Type of comparative bioavailability study designed in such a way as to take into account differences in bioavailability arising from differences between patients suffering from disease
Pharmaceutics Pharmacist Competitive Exams
Q. Type of comparative bioavailability study designed in such a way as to take into account differences in bioavailability arising from differences between patients suffering from disease
Ans → crossover study
Explanation →
This question is taken from the test/quiz post: one liners Pharmaceutics| B.Pharmacy| Pharmacy file-3 - attemp/practice
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Q. An Obstacle such as coating or embedding, which acts as a factor controlling the rate of drug release.
Ans → diffusion barrier
Explanation →
Q. Name a stage in the drying of solids, above which the drying rate is linear, at which the drying rate ceases to be linear, until it reaches the equilibrium moisture content.
Ans → critical moisture content
Explanation →
Q. Formulation in which individual doses of a granulated dosage form are separated
Ans → divided granule
Explanation →
Q. Type of comparative bioavailability study designed in such a way as to take into account differences in bioavailability arising from differences between patients suffering from disease
Ans → crossover study
Explanation →
Q. Powder formulation in which individual doses of a powdered dosage form are separately wrapped
Ans → divided powder
Explanation →
Q. Name term that describes a solid of regular shape and the presence of three-dimensional order on the level of atomic dimensions, for a given molecule.
Ans → crystalline
Explanation →
Q. A Formulated preparation of molecules/drugs that are rarely if ever suitable for administration to patients without additives.
Ans → dosage form
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Q. Dosage form in which the active ingredient is insoluble in the carrier; includes aerosols, suspensions, emulsions , and foams
Ans → disperse system
Explanation →
Q. A Biologically active substance, which when biodistributed in the body is expected to modify one or more of its functions.
Ans → drug
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Q. Solid preparation that on contact with water breaks apart by the effect of gas evolution, resulting commonly from the reaction of hydrogen carbonate with citric or tartaric acid, in order to facilitate dissolution or dispersion of the active ingredient before ingestion.
Ans → effervescent tablet
Explanation →
Q. Opposite of deliquescence; the drying of a salt solution when the vapour pressure of water in the saturated solution of a substance is greater than the partial pressure of water in the ambient air.
Ans → efflorescence
Explanation →
Q. Name a technological process, which consists of mixing or inclusion of the therapeutic substance with an excipient or their mixtures, typically as a matrix dosage form, in order to change the rate of release.
Ans → embedding
Explanation →
Q. Sweet (often colored) dilute alcohol-based, “hydroalcoholic”, liquid used in the compounding of drugs to be taken by mouth in order to improve palatability.
Ans → elixir
Explanation →
Q. The process of separating the lighter particles of a powder from the heavier ones by means of an upward-directed stream of fluid
Ans → elutriation
Explanation →
Q. Name a substance that loses water to form a lower hydrate or becomes anhydrous spontaneously.
Ans → efflorescent
Explanation →
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Q. An Obstacle such as coating or embedding, which acts as a factor controlling the rate of drug release.
Ans → diffusion barrier
Explanation →
Q. Process that differentiates or separates solid particles according to their size using a meshed or perfo- rated device.
Ans → sieving
Explanation →
Q. Dosage form, semi-solid, used for the administration of drugs via the rectal route, for systemic or local effect.
Ans →
Explanation →
Q. The name of the protein that has been identified to serve as a primer for glycogen synthesis is
Ans → Glycogenin
Explanation →
Q. Class of antibacterials that inhibit cell wall synthesis by binding to peptidoglycan subunits and blocking their insertion into the cell wall
Ans → glycopeptides
Explanation →
Q. Inflammation of the conjunctiva in newborns caused by Neisseria gonorrhoeae transmitted during childbirth
Ans → ophthalmia neonatorum
Explanation →
Q. The oxidation of ferrous (Fe2+) iron to ferric (Fe3+) iron in hemoglobin results in the formation of a compound namely
Ans → Methemoglobin
Explanation →
Q. Initial, typically larger than the maintenance dose of a drug given to a patient at the start of pharmacotherapy.
Ans → loading dose
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Q. The specific term used to describe carbohydrate stereoisomers differing only in configuration at the hemi-acetal carbon atom.
Ans → anomers
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Q. Relative amount of the administered dose of a drug that reaches systemic circulation from a certain dosage form in comparison to the amount that reaches the systemic circulation by iv administration
Ans → bioavailability
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Q. The particular order in which electrons are arranged in an atom or molecule.
Ans → electronic configuration
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Q. The clones of cell produced by fusing a normal B cell with a myeloma cell that is capable of producing monoclonal antibodies indefinitely
Ans → hybridoma
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Q. Name the stage of replication during which various proteins bind to the origin of replication to begin the replication process
Ans → initiation of DNA replication
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Q. Sweet (often colored) dilute alcohol-based, “hydroalcoholic”, liquid used in the compounding of drugs to be taken by mouth in order to improve palatability.
Ans → elixir
Explanation →
Q. Name the types of host cells that a particular virus is able to infect
Ans → host range
Explanation →
Q. The coenzyme that participates in transamination reactions is
Ans → Pyridoxal phosphate
Explanation →
Q. A graph of the energy of a reaction against the progress of the reaction.
Ans → energy diagram
Explanation →
Q. A formal non-ambiguous, nomenclature system for the assignment of absolute configuration of structure to chiral atoms, using the Cahn, Ingold and Prelog priority rules.
Ans → R,S convention
Explanation →
Q. Proteins that participate in ribosome assembly during initiation
Ans → initiation factors
Explanation →
Q. Name the hyperthyroidism caused by an autoimmune disease affecting thyroid function
Ans → Graves disease
Explanation →
Q. Name the class of antibacterials that inhibit cell wall synthesis by binding to peptidoglycan subunits and blocking their insertion into the cell wall backbone.
Ans → glycopeptides
Explanation →
Q. Name the most serious stage of pertussis (whooping cough), characterized by severe and prolonged coughing spells
Ans → paroxysmal stage
Explanation →
Q. It occurs when a hydrogen atom has an electromagnetic attractive interaction with an electronegative atom.
Ans → Hydrogen Bonding
Explanation →
Q. Process by which food is rendered free from pathogenic, toxigenic, and spoilage organisms.
Ans → appertization
Explanation →
Q. Release of a drug from a dosage form that it is not immediate
Ans → modified release
Explanation →