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Name the antiviral drugs that block the activity of the HIV integrase responsible for recombination of a DNA copy of the viral genome into the host cell chromosome
Microbiology Pharmacist Competitive Exams
Q. Name the antiviral drugs that block the activity of the HIV integrase responsible for recombination of a DNA copy of the viral genome into the host cell chromosome
Ans → integrase inhibitors
Explanation →
This question is taken from the test/quiz post: Microbiology Important Questions (One Liners Set - 8) | Pharmacy - attemp/practice
More oneliners in - Microbiology Important Questions (One Liners Set - 8) | Pharmacy
Q. Name a group of common sexually transmitted viruses that may be associated with genital warts or with cervical cancer
Ans → human papillomavirus (HPV)
Explanation →
Q. Name adaptive immunity mediated by antibodies produced by B cells
Ans → humoral immunity
Explanation →
Q. Name the stage of replication during which various proteins bind to the origin of replication to begin the replication process
Ans → initiation of DNA replication
Explanation →
Q. Name the stage of transcription during which RNA polymerase binds to a promoter and transcription begins
Ans → initiation of transcription
Explanation →
Q. Name a microorganism that has an optimum growth temperature close to the temperature of boiling water
Ans → hyperthermophile
Explanation →
Q. Name the type of mutation involving the addition of one or more bases into a DNA sequence
Ans → insertion
Explanation →
Q. Name the term that refers to a nonpolar molecule or portion of a molecule not capable of strong attraction to water molecules
Ans → hydrophobic
Explanation →
Q. Name the antiviral drugs that block the activity of the HIV integrase responsible for recombination of a DNA copy of the viral genome into the host cell chromosome
Ans → integrase inhibitors
Explanation →
Q. Name the molecule that slides between the stacked nitrogenous bases of the DNA double helix, potentially resulting in a frameshift mutation
Ans → intercalating agent
Explanation →
Q. Name the term that refers to a polar molecule or portion of a molecule capable of strong attraction to water molecules
Ans → hydrophilic
Explanation →
Q. The distortion of a light wave due to interaction with another wave
Ans → interference
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Q. Cytokines released by cells that have been infected with a virus; stimulate antiviral responses in nearby cells as well as the cells secreting the interferons
Ans → interferons
Explanation →
Q. The clones of cell produced by fusing a normal B cell with a myeloma cell that is capable of producing monoclonal antibodies indefinitely
Ans → hybridoma
Explanation →
Q. Cytokines largely produced by immune system cells that help coordinate efforts against invading pathogens
Ans → interleukins
Explanation →
Q. Name the enzyme produced by pathogens that degrades hyaluronic acid between adjacent cells in connective tissue
Ans → hyaluronidase
Explanation →
More one-liners in - Microbiology
Q. An antibacterial and antiprotozoan drug of the nitroimidazole class that is activated in anaerobic target cell and introduces DNA strand breakage, thus interfering with DNA replication in target cells
Ans → metronidazole
Explanation →
Q. Process that differentiates or separates solid particles according to their size using a meshed or perfo- rated device.
Ans → sieving
Explanation →
Q. Visible clumping of red blood cells that can be caused by some viruses, bacteria, and certain diseases in which antibodies
Ans → hemagglutination
Explanation →
Q. When particles move to a lower area of concentration from a high area of concentration.
Ans → diffusion
Explanation →
Q. A form of microbial control using heat that is applied to foods; kills pathogens and reduces the number of spoilage-causing microbes while maintaining food quality
Ans → pasteurization
Explanation →
Q. A ligand that binds to a receptor and alters the receptor state resulting in a biological response.
Ans → Agonist
Explanation →
Q. Type of mutation involving the addition of one or more bases into a DNA sequence
Ans → insertion
Explanation →
Q. Name the organism that uses fixed organic carbon compounds as its carbon source
Ans → heterotroph
Explanation →
Q. A a special objective lens on a microscope designed to be used with immersion oil to improve resolution
Ans → oil immersion lens
Explanation →
Q. Insertion or grafting of a biological, living, inert, or radioactive material into the body.
Ans → implantation
Explanation →
Q. The movement of chemicals (drugs) into, through, and out of biological organisms or their parts.
Ans → Biotranslocation
Explanation →
Q. The process of separation of a racemate into its two enantiomers by means of some chiral agency.
Ans → resolution
Explanation →
Q. Device that disperses liquids to aerosols for therapeutic use by inhalation through a mask.
Ans → nebulizer
Explanation →
Q. Existence of two or more different crystal structures for the same compound.
Ans → polymorphism
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Q. The enzyme defect in acute intermittent porphyria
Ans → Uroporphyrinogen synthase I
Explanation →
Q. The cofactor required for the conversion of phenylalanine to tyrosine is
Ans → Tetrahydrobiopterin
Explanation →
Q. The member of the quinolone family that functions by inhibiting the activity of DNA gyrase, blocking DNA replication
Ans → nalidixic acid
Explanation →
Q. Name the most serious stage of pertussis (whooping cough), characterized by severe and prolonged coughing spells
Ans → paroxysmal stage
Explanation →
Q. The disease characterized by impairment in the absorption of neutral amino acids
Ans → Hartnup’s disease
Explanation →
Q. Molecules that have the same molecular formula and sequence of atoms yet differ in their 3-D orientation.
Ans → Stereoisomer
Explanation →
Q. A process in which the forward reaction can reach an equilibrium with the reverse reaction.
Ans → reversible process
Explanation →
Q. A ring structure formed from complement proteins C6 through C9 that penetrates the membranes of a targeted cell, causing cell lysis and death
Ans → membrane attack complex (MAC)
Explanation →
Q. Anti-tuberculosis drug, isonicotinic acid hydrazide (INH) leads to the deficiency of vitamin
Ans → Pyridoxine (B6)
Explanation →
Q. Name the enzyme produced by pathogens that degrades hyaluronic acid between adjacent cells in connective tissue
Ans → hyaluronidase
Explanation →
Q. An instrument used to measure the amount of rotation of plane polarized light by a compound, generally prepared in a solution
Ans → polarimeter
Explanation →
Q. the method for producing gasoline from heavy petroleum distillates.
Ans → catalytic cracking
Explanation →
Q. The the sequencing of genomic fragments from microbial communities, allowing researchers to study genes from a collection of multiple species
Ans → metagenomics
Explanation →
Q. The the sequencing of genomic fragments from microbial communities, allowing researchers to study genes from a collection of multiple species
Ans → metagenomics
Explanation →
Q. Sequenator is an automatic machine to determine amino acid sequence in a polypeptide chain. The reagent used in sequenator is
Ans → Edman’s reagent
Explanation →
Q. It is the ability of the specific adaptive immune system to quickly respond to pathogens to which it has previously been exposed
Ans → memory
Explanation →
Q. The ability of electrons to "shuffle," or alternate, between bonds, making the molecule extremely stable. The best example of this is benzene.
Ans → Resonance
Explanation →
Q. Name the bacteria that have more than 50% guanine and cytosine nucleotides in their DNA
Ans → high G+C gram-positive bacteria
Explanation →
Q. Repair of the sugar-phosphate backbone of the DNA, making the DNA molecule continuous
Ans → ligation
Explanation →
Q. The number of mg of KOH required to hydrolyse 1 g fat or oil is known as
Ans → Saponification number
Explanation →
Q. Measure of the fraction of a given drug that is absorbed intact into the systemic circulation from a dosage form, relative to a recognized, clinically proven, standard dosage form of that drug.
Ans → relative bioavailability
Explanation →
Q. Name a microorganism that has an optimum growth temperature close to the temperature of boiling water
Ans → hyperthermophile
Explanation →