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Sickling of RBC in sickle-cell anemia is due to polymerization of
Biochemistry Pharmacist Competitive Exams
Q. Sickling of RBC in sickle-cell anemia is due to polymerization of
Ans → Deoxyhemoglobin,
Explanation →
This question is taken from the test/quiz post: Biochemistry Important One Liners Questions On HEMOGLOBIN AND PORPHYRINS - attemp/practice
More oneliners in - Biochemistry Important One Liners Questions On HEMOGLOBIN AND PORPHYRINS
Q. The oxidation of ferrous (Fe2+) iron to ferric (Fe3+) iron in hemoglobin results in the formation of a compound namely
Ans → Methemoglobin
Explanation →
Q. Name the compound that is increased in RBC of anemic patients to facilitate the supply of O2 to the tissues
Ans → 2,3-Bisphosphoglycerate
Explanation →
Q. Sickling of RBC in sickle-cell anemia is due to polymerization of
Ans → Deoxyhemoglobin,
Explanation →
Q. The disorders characterized by decreased synthesis or total absence of globin chains of hemoglobin are collectively known as
Ans → Thalassemias
Explanation →
Q. The intermediate of citric acid cycle that is involved in heme synthesis
Ans → Succinyl CoA
Explanation →
Q. The enzyme defect in acute intermittent porphyria
Ans → Uroporphyrinogen synthase I
Explanation →
Q. The enzyme that is regulated by feedback inhibition in heme synthesis is
Ans → δ -Aminolevulinate synthase
Explanation →
Q. The compound that facilitates the release of O2 from oxyhemoglobin
Ans → C1– , H+ , 2, 3-BPG
Explanation →
Q. Name the amino acid that directly participates in the synthesis of heme
Ans → Glycine
Explanation →
More one-liners in - Biochemistry
Q. An equimolar mixture of the two enantiomeric isomers of a compound.
Ans → racemic mixture
Explanation →
Q. The sideways projection of a carbon-carbon single bond and the attached substituents.
Ans → sawhorse projection
Explanation →
Q. Name the type of mutation involving the addition of one or more bases into a DNA sequence
Ans → insertion
Explanation →
Q. The regulatory enzyme in the pyrimidine biosynthesis in animals is
Ans → Carbamoyl phosphate synthetase II
Explanation →
Q. The amino acids required for the synthesis of purines and pyrimidines are
Ans → Glutamine and aspartate
Explanation →
Q. A a stain that produces colour around the structure of interest while not coloring the structure itself
Ans → negative stain
Explanation →
Q. Specific case of drug embedding in insoluble excipients (typically in a polymer) in order to achieve extended release.
Ans → matrix formulation
Explanation →
Q. Isomers that differ in the order the atoms are placed. They have the same number of atoms, just in a different order.
Ans → Constitutional Isomers
Explanation →
Q. The most important carbohydrate associated with flatulence caused by ingestion of leguminous seeds
Ans → Raffinose
Explanation →
Q. Serious infection caused by Trypanosoma brucei and spread by the bite of the tsetse fly
Ans → human African trypanosomiasis
Explanation →
Q. The third stage of acute disease, during which the number of pathogens present in the host is greatest and the signs and symptoms of disease are most severe
Ans → period of illness
Explanation →
Q. The process by which DNA from one organism is cut and new pieces of foreign DNA from a second organism are inserted,
Ans → recombinant DNA technology
Explanation →
Q. An adaptive immune defenses received from another individual or animal
Ans → passive immunity
Explanation →
Q. Technique in which antibody or antigen can be concentrated by passing fluids through porous membranes, and target molecules are captured as they pass
Ans → immunofiltration
Explanation →
Q. A a DNA molecule resulting from the cutting and insertion of DNA from one organism into the DNA of another organism, resulting in a new combination of genetic material
Ans → recombinant DNA molecule
Explanation →
Q. A type of inclusion containing volutin, a polymerized inorganic phosphate that appears red when stained with methylene blue
Ans → metachromatic granule
Explanation →
Q. A term applied an object or molecule that does not possess symmetry.
Ans → asymmetry
Explanation →
Q. Anti-tuberculosis drug, isonicotinic acid hydrazide (INH) leads to the deficiency of vitamin
Ans → Pyridoxine (B6)
Explanation →
Q. Process in which powder particles are made to aggregate to larger particles called granules.
Ans → granulation
Explanation →
Q. An organism that requires oxygen at levels lower than atmospheric concentration
Ans → microaerophile
Explanation →
Q. The ‘burning feet syndrome’ in man is associated with the deficiency of
Ans → Pantothenic acid
Explanation →
Q. Lowest concentration of an antibacterial drug necessary to inhibit the growth of a microorganism.
Ans → minimum inhibitory concentration (MIC)
Explanation →