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Which one is the alkylating anticancer drug?

Pharmacy Pharmacology Biomedical Science D. Pharma B. Pharma General Pharmacology General Pharmacology

Q. 29 of Quiz-266 (Que-ID : 672)

Which one is the alkylating anticancer drug?

  • Fluorouracil
  • Vincristine
  • Thiotepa
  • Doxorubicin

Ans → (c)Thiotepa

Explanation → Thiotepa is an organophosphorus compound, is an alkylating anticancer drug.

This question is taken from this post → Classification of drugs in pharmacology Aptitude Test - attemp/practice


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Q. 1 of Quiz-266 (Que-ID : 411)

Suganril is common brand name for:

  • Phenylbutazone
  • Piroxican
  • Benorylate
  • Indomethacin

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Q. 2 of Quiz-266 (Que-ID : 643)

Which one of these is μ-opioid agonist?

  • Pethidine
  • Codeine
  • Nalorphine
  • None of these

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Q. 3 of Quiz-266 (Que-ID : 644)

Levodopa is amino acid precursor of - 

  • Adrenaline
  • Dopamine
  • Norepinephrine
  • All of these

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Q. 4 of Quiz-266 (Que-ID : 645)

The most potent CNS stimulant among xanthine bases are-

  • Theophylline
  • Caffeine
  • Theobromine
  • All of these

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Q. 5 of Quiz-266 (Que-ID : 646)

Chlorpromazine is useful in the treatment of -

  • Mental depression
  • Schizophrenia
  • Parkinsonism
  • None of the above

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Q. 6 of Quiz-266 (Que-ID : 649)

Amlodepine Lowers blood pressure by-

  • Inhibition of calcium influx
  • Inhibition of angiotensin converting enzyme (ACE)
  • Blocking norepinephrine reuptake
  • All of the above

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Q. 7 of Quiz-266 (Que-ID : 650)

Cholestyramine is useful in the treatment of -

  • Arrhythmia
  • Hypertension
  • Hyper lipoproteinemia
  • Angina pectoris

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Q. 8 of Quiz-266 (Que-ID : 651)

Clofibrate mainly Lowers the -

  • LDL
  • VLDL
  • HDL
  • Chylomicrons

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Q. 9 of Quiz-266 (Que-ID : 652)

Lovastatin is useful in -

  • High blood pressure
  • Arrhythmia
  • Hyper lipoproteinemia
  • Angina pectoris

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Q. 10 of Quiz-266 (Que-ID : 653)

Oral anticoagulants act by antagonising the actions of -

  • Calcium ion
  • Prothrombin
  • Vitamin K
  • Fibrinogen

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Q. 11 of Quiz-266 (Que-ID : 654)

Glucocorticoid are used in the treatment of :

  • Inflammation
  • Inflammation and allergy
  • Skin infections
  • Allergy

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Q. 12 of Quiz-266 (Que-ID : 655)

The sulphonamides are :

  • Bactericidal in nature
  • Bacteriostatic in nature
  • Bactericidal only at high dose
  • None of the above

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Q. 13 of Quiz-266 (Que-ID : 656)

Tetracycline act by -

  • Inhibition of protein synthesis
  • Interfering in cell wall synthesis
  • Altering the permeability of cell membrane of organism
  • All of the above

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Q. 14 of Quiz-266 (Que-ID : 657)

Nystatin is principally effective in:

  • Candidia albicans
  • Blastomyces
  • Cryptococcus histoplasma
  • All of the above

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Q. 15 of Quiz-266 (Que-ID : 658)

Pyridoxine is administered with isoniazid to minimise the:

  • Hepatotoxicity
  • Neurotoxicity
  • Nephrotoxicity
  • Allergic reaction

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Q. 16 of Quiz-266 (Que-ID : 659)

Which one of these combination is used in Chloroquine resistance malaria?

  • Trimethoprim + pyrimethamine
  • Pyrimethamine + sulphadoxine
  • Mefloquine + Primaquine
  • None of the above

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Q. 17 of Quiz-266 (Que-ID : 660)

Which one of the enzyme is used in the treatment of cancer?

  • L- asparginase
  • Phosphodiesterase
  • Xanthine Oxidase
  • None of the above

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Q. 18 of Quiz-266 (Que-ID : 661)

Eserine acts by -

  • Receptor mechanism
  • Acting on cell membrane
  • Drug-enzyme interactions
  • None of the above

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Q. 19 of Quiz-266 (Que-ID : 662)

Desferrioxamine is a :

  • Chelating agent
  • Antimetabolite
  • Enzyme inhibitor
  • None of the above

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Q. 20 of Quiz-266 (Que-ID : 663)

Sodium valproate prevent the epileptic seizure by -

  • Depressing the CNS
  • Preventing influx of sodium
  • Preventing influx of calcium
  • None of the above

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Q. 21 of Quiz-266 (Que-ID : 664)

Which one of these is used with hyoscine to induce Twilight sleep?

  • Pentazocine
  • Pethidine
  • Diphenhydramine
  • None of the above

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Q. 22 of Quiz-266 (Que-ID : 665)

Ergot preparations are useful in migraine due to its-

  • Oxytocic action
  • Vasoconstriction action
  • α -receptors blocking action
  • None of the above

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Q. 23 of Quiz-266 (Que-ID : 666)

Which one of these is a major tranquilizer?

  • Phenelzine
  • Promethazine
  • Trifluoperazine
  • Hydroxyzine

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Q. 24 of Quiz-266 (Que-ID : 667)

Which one is a cholinomimetic agent?

  • Atropine
  • Salbutamol
  • Tolbutamide
  • Acetylcholine

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Q. 25 of Quiz-266 (Que-ID : 668)

Testosterone is not orally active because?

  • React with acid
  • Degradation
  • Reduction
  • Rapid oxidation of 17-hydroxy group to ketones

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Q. 26 of Quiz-266 (Que-ID : 669)

Which one of the following drug shows antiplatelet activity?

  • Verapamil
  • Nifedipine
  • Warferin
  • Dipyridamole

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Q. 27 of Quiz-266 (Que-ID : 670)

Nociceptors are associated with:

  • Chemical
  • Pain
  • Temperature
  • Pressure

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Q. 28 of Quiz-266 (Que-ID : 671)

Drug that shows selective antagonistic selective H1 antagonistic action?

  • Chlorpheniramine
  • Cimetidine
  • Ranitidine
  • Thioperamide

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Q. 29 of Quiz-266 (Que-ID : 672)

Which one is the alkylating anticancer drug?

  • Fluorouracil
  • Vincristine
  • Thiotepa
  • Doxorubicin

Discuss View Answer

Q. 30 of Quiz-266 (Que-ID : 673)

Which one is a HMGC A reductase inhibitor?

  • Rhabdomylosis
  • Nausea
  • Vomiting
  • Rise in serum transaminase

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More MCQs In - Pharmacy Pharmacology Biomedical Science D. Pharma B. Pharma General Pharmacology General Pharmacology

Q. 9 of Quiz- (Que-ID : 186)

Which one of these metallic ions essential for coagulation of blood?

  • Calcium
  • Manganese
  • Sodium
  • Potassium

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Q. 20 of Quiz- (Que-ID : 1849)

Tocoferol also known as-

  • Vitamin D
  • Vitamin E
  • Vitamin B
  • Vitamin K

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Q. 1 of Quiz- (Que-ID : 1485)

Compared to subcutaneous injection, the intramus- cular injection of drugs:

  • Is more painful
  • Produces faster response
  • Is unsuitable for depot preparations
  • Carries greater risk of anaphylactic reaction

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Q. 3 of Quiz- (Que-ID : 1832)

Water borne disease is-

  • Tuberculosis
  • cholera
  • measles
  • influenza

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Q. 36 of Quiz- (Que-ID : 123)

Plasma protiens act as

  • Reserve protiens
  • Immunoglobulins
  • Buffers
  • All of these

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Q. 8 of Quiz- (Que-ID : 1565)

Simple syrup is a saturated solution of…

  • Fructose
  • Mannose
  • Glucose
  • Sucrose

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Q. 16 of Quiz- (Que-ID : 1050)

Spermatozoa are formed in

  • Vasa deference
  • Prostate gland
  • Seminal vesicles
  • None of the above

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Q. 21 of Quiz- (Que-ID : 1114)

The pentothal sodium is a -

  • Local anesthetic
  • Intravenous anesthetic
  • General anesthetic
  • Hypnotic

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Q. 1 of Quiz- (Que-ID : 452)

The peptide bond in proteins is detected by

  • Biuret test
  • formaldehyde
  • Million test
  • water

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Q. 4 of Quiz- (Que-ID : 1470)

Vaginal suppositories are also known as …

  • Gels
  • Liniments
  • Poultice
  • Pessaries

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Q. 16 of Quiz- (Que-ID : 1325)

The maximum number of members in public limited company is-

  • 20
  • 30
  • 50
  • unlimited

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Q. 8 of Quiz- (Que-ID : 484)

Tonsils are present in

  • Pharynx
  • Larynx
  • Pancreas
  • Liver

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Q. 7 of Quiz- (Que-ID : 7)

Caraway Oil contains :

  • Phellandrene
  • Pinene
  • Carvone
  • Cineole

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Q. 17 of Quiz- (Que-ID : 1140)

Which fatty base is used in suppositories?

  • Witespol
  • Massupol
  • Cocoa butter
  • Soap glycerin base

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Q. 16 of Quiz- (Que-ID : 633)

The Insecticide act was passed in the year - 

  • 1968
  • 1960
  • 1965
  • 1967

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Q. 15 of Quiz- (Que-ID : 658)

Pyridoxine is administered with isoniazid to minimise the:

  • Hepatotoxicity
  • Neurotoxicity
  • Nephrotoxicity
  • Allergic reaction

Discuss View Answer

Q. 8 of Quiz- (Que-ID : 3908)

Hyperlipidemia is excess of

  • Cholesterol and triglycerides
  • Free fatty acids
  • Glucose
  • Ketone bodies

Discuss View Answer

Q. 36 of Quiz- (Que-ID : 123)

Plasma protiens act as

  • Reserve protiens
  • Immunoglobulins
  • Buffers
  • All of these

Discuss View Answer

Directions : For each question, choose a correct option from given four options (A, B, C and D)

Q. 13 of Quiz- (Que-ID : 1227)

Which forcep is used to hold the appendix?

  • Alli's tissue forcep
  • Badcock's forcep
  • Lan's tissue forcep
  • all of the above

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Q. 10 of Quiz- (Que-ID : 1567)

When the action of the drug is opposed by the other drug, the the phenomenon is known as

  • Antagonism
  • Synergism
  • Opposition
  • Potentisation

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Q. 27 of Quiz- (Que-ID : 670)

Nociceptors are associated with:

  • Chemical
  • Pain
  • Temperature
  • Pressure

Discuss View Answer

Q. 25 of Quiz- (Que-ID : 668)

Testosterone is not orally active because?

  • React with acid
  • Degradation
  • Reduction
  • Rapid oxidation of 17-hydroxy group to ketones

Discuss View Answer

Q. 5 of Quiz- (Que-ID : 1532)

Which term refers to the back of the knee?

  • popliteal
  • pelvic
  • pedal
  • perineal

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Q. 12 of Quiz- (Que-ID : 2224)

Which statement below is correct for cathartics?

  • Agents which reduce the evacuation of bowels
  • Agents which is used in case of diarrhoea
  • Agents which is used in case of acidosis
  • Agents which fastens and increase evacuation of bowels

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Q. 9 of Quiz- (Que-ID : 1269)

The absorption rate is faster for-

  • Capsule
  • Tablet
  • Coated tablet
  • Solution

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Q. 6 of Quiz- (Que-ID : 1513)

Select the drug which is administered orally for erectile dysfunction in men

  • Albendazole
  • Mebendazole
  • Cocaine
  • Sildenafil

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Q. 5 of Quiz- (Que-ID : 2207)

Which one of these is used in sunburns?

  • Titanium oxide
  • Potassium iodide
  • Boric acid
  • Calamine

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Q. 4 of Quiz- (Que-ID : 1187)

alpha numeric codification is suitable for a -

  • Large scale organisation
  • Small scale organisation
  • Medium scale organisation
  • All of the above

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Q. 45 of Quiz- (Que-ID : 132)

An anti-arrythmic drug that is also used to control seizures is

  • Lidocain
  • Disipyramide
  • Phenytoin
  • Amiodarone

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Q. 22 of Quiz- (Que-ID : 1372)

The main ring structure is present in tryptophan is-

  • Indole
  • imidazole
  • furan
  • thiophane

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Q. 16 of Quiz- (Que-ID : 103)

Which of the following metabolite of cyclophosphamide is responsible for its anti-tumor actitivity?

  • Phosphoramide mustard
  • Acrolein
  • Aldophosphamide
  • 4-hydroxy cyclophosphamide

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Q. 10 of Quiz- (Que-ID : 1819)

Niclosamide is used in the infection caused by-

  • Nematodes
  • Cestodes
  • Trematodes
  • all of the above

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Q. 10 of Quiz- (Que-ID : 1688)

Iodine dissolves in water with the addition of-

  • Sodium chloride
  • Sulphur
  • Potassium iodide
  • Calcium carbonate

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Q. 23 of Quiz- (Que-ID : 1206)

A person who is interested to start a retail drug store must be -

  • D.Pharmacy
  • Registered Pharmacist
  • Chemist
  • Druggist

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Q. 16 of Quiz- (Que-ID : 659)

Which one of these combination is used in Chloroquine resistance malaria?

  • Trimethoprim + pyrimethamine
  • Pyrimethamine + sulphadoxine
  • Mefloquine + Primaquine
  • None of the above

Discuss View Answer

Q. 1 of Quiz- (Que-ID : 1508)

Labetalol differs from propranolol in that

  • It has additional α1 blocking property
  • It is a selective βS1 blocker
  • It does not undergo first pass metabolism
  • All of the above

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Q. 24 of Quiz- (Que-ID : 667)

Which one is a cholinomimetic agent?

  • Atropine
  • Salbutamol
  • Tolbutamide
  • Acetylcholine

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Q. 6 of Quiz- (Que-ID : 1684)

The colour of the cylinder of nitrous oxide is-

  • Red
  • Blue
  • Black
  • Orange

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Q. 19 of Quiz- (Que-ID : 495)

Ciliary body in the eye ball is the extension of:

  • Sclera
  • Choroid
  • Retina
  • cornea

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Q. 62 of Quiz- (Que-ID : 239)

The 5,5-diphenyl-2,4-imidazolidinedione monosodium is used as:

  • Hypnotic
  • Anticonvulsant
  • Muscle relexant
  • Muscarinic agent

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Directions : For each question, choose a correct option from given four options (A, B, C and D)

Q. 29 of Quiz- (Que-ID : 1243)

Number of pharmacists required in a 300 bed hospital?

  • 3
  • 5
  • 8
  • 10

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