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Pyridoxine is administered with isoniazid to minimise the:

Pharmacy Pharmacology Biomedical Science D. Pharma B. Pharma General Pharmacology General Pharmacology

Q. 15 of Quiz-266 (Que-ID : 658)

Pyridoxine is administered with isoniazid to minimise the:

  • Hepatotoxicity
  • Neurotoxicity
  • Nephrotoxicity
  • Allergic reaction

Ans → (c)Nephrotoxicity

Explanation → Pyridoxine is also called vitamin B6, assist in the balancing of sodium and potassium as well as promoting RBC.

This question is taken from this post → Classification of drugs in pharmacology Aptitude Test - attemp/practice


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Q. 1 of Quiz-266 (Que-ID : 411)

Suganril is common brand name for:

  • Phenylbutazone
  • Piroxican
  • Benorylate
  • Indomethacin

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Q. 2 of Quiz-266 (Que-ID : 643)

Which one of these is μ-opioid agonist?

  • Pethidine
  • Codeine
  • Nalorphine
  • None of these

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Q. 3 of Quiz-266 (Que-ID : 644)

Levodopa is amino acid precursor of - 

  • Adrenaline
  • Dopamine
  • Norepinephrine
  • All of these

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Q. 4 of Quiz-266 (Que-ID : 645)

The most potent CNS stimulant among xanthine bases are-

  • Theophylline
  • Caffeine
  • Theobromine
  • All of these

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Q. 5 of Quiz-266 (Que-ID : 646)

Chlorpromazine is useful in the treatment of -

  • Mental depression
  • Schizophrenia
  • Parkinsonism
  • None of the above

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Q. 6 of Quiz-266 (Que-ID : 649)

Amlodepine Lowers blood pressure by-

  • Inhibition of calcium influx
  • Inhibition of angiotensin converting enzyme (ACE)
  • Blocking norepinephrine reuptake
  • All of the above

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Q. 7 of Quiz-266 (Que-ID : 650)

Cholestyramine is useful in the treatment of -

  • Arrhythmia
  • Hypertension
  • Hyper lipoproteinemia
  • Angina pectoris

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Q. 8 of Quiz-266 (Que-ID : 651)

Clofibrate mainly Lowers the -

  • LDL
  • VLDL
  • HDL
  • Chylomicrons

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Q. 9 of Quiz-266 (Que-ID : 652)

Lovastatin is useful in -

  • High blood pressure
  • Arrhythmia
  • Hyper lipoproteinemia
  • Angina pectoris

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Q. 10 of Quiz-266 (Que-ID : 653)

Oral anticoagulants act by antagonising the actions of -

  • Calcium ion
  • Prothrombin
  • Vitamin K
  • Fibrinogen

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Q. 11 of Quiz-266 (Que-ID : 654)

Glucocorticoid are used in the treatment of :

  • Inflammation
  • Inflammation and allergy
  • Skin infections
  • Allergy

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Q. 12 of Quiz-266 (Que-ID : 655)

The sulphonamides are :

  • Bactericidal in nature
  • Bacteriostatic in nature
  • Bactericidal only at high dose
  • None of the above

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Q. 13 of Quiz-266 (Que-ID : 656)

Tetracycline act by -

  • Inhibition of protein synthesis
  • Interfering in cell wall synthesis
  • Altering the permeability of cell membrane of organism
  • All of the above

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Q. 14 of Quiz-266 (Que-ID : 657)

Nystatin is principally effective in:

  • Candidia albicans
  • Blastomyces
  • Cryptococcus histoplasma
  • All of the above

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Q. 15 of Quiz-266 (Que-ID : 658)

Pyridoxine is administered with isoniazid to minimise the:

  • Hepatotoxicity
  • Neurotoxicity
  • Nephrotoxicity
  • Allergic reaction

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Q. 16 of Quiz-266 (Que-ID : 659)

Which one of these combination is used in Chloroquine resistance malaria?

  • Trimethoprim + pyrimethamine
  • Pyrimethamine + sulphadoxine
  • Mefloquine + Primaquine
  • None of the above

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Q. 17 of Quiz-266 (Que-ID : 660)

Which one of the enzyme is used in the treatment of cancer?

  • L- asparginase
  • Phosphodiesterase
  • Xanthine Oxidase
  • None of the above

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Q. 18 of Quiz-266 (Que-ID : 661)

Eserine acts by -

  • Receptor mechanism
  • Acting on cell membrane
  • Drug-enzyme interactions
  • None of the above

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Q. 19 of Quiz-266 (Que-ID : 662)

Desferrioxamine is a :

  • Chelating agent
  • Antimetabolite
  • Enzyme inhibitor
  • None of the above

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Q. 20 of Quiz-266 (Que-ID : 663)

Sodium valproate prevent the epileptic seizure by -

  • Depressing the CNS
  • Preventing influx of sodium
  • Preventing influx of calcium
  • None of the above

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Q. 21 of Quiz-266 (Que-ID : 664)

Which one of these is used with hyoscine to induce Twilight sleep?

  • Pentazocine
  • Pethidine
  • Diphenhydramine
  • None of the above

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Q. 22 of Quiz-266 (Que-ID : 665)

Ergot preparations are useful in migraine due to its-

  • Oxytocic action
  • Vasoconstriction action
  • α -receptors blocking action
  • None of the above

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Q. 23 of Quiz-266 (Que-ID : 666)

Which one of these is a major tranquilizer?

  • Phenelzine
  • Promethazine
  • Trifluoperazine
  • Hydroxyzine

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Q. 24 of Quiz-266 (Que-ID : 667)

Which one is a cholinomimetic agent?

  • Atropine
  • Salbutamol
  • Tolbutamide
  • Acetylcholine

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Q. 25 of Quiz-266 (Que-ID : 668)

Testosterone is not orally active because?

  • React with acid
  • Degradation
  • Reduction
  • Rapid oxidation of 17-hydroxy group to ketones

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Q. 26 of Quiz-266 (Que-ID : 669)

Which one of the following drug shows antiplatelet activity?

  • Verapamil
  • Nifedipine
  • Warferin
  • Dipyridamole

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Q. 27 of Quiz-266 (Que-ID : 670)

Nociceptors are associated with:

  • Chemical
  • Pain
  • Temperature
  • Pressure

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Q. 28 of Quiz-266 (Que-ID : 671)

Drug that shows selective antagonistic selective H1 antagonistic action?

  • Chlorpheniramine
  • Cimetidine
  • Ranitidine
  • Thioperamide

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Q. 29 of Quiz-266 (Que-ID : 672)

Which one is the alkylating anticancer drug?

  • Fluorouracil
  • Vincristine
  • Thiotepa
  • Doxorubicin

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Q. 30 of Quiz-266 (Que-ID : 673)

Which one is a HMGC A reductase inhibitor?

  • Rhabdomylosis
  • Nausea
  • Vomiting
  • Rise in serum transaminase

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Q. 5 of Quiz- (Que-ID : 1572)

One of the functions of bones is to make red blood cells. What is this process known as?

  • Haemopoiesis
  • Haematuria
  • Haemostasis
  • Haemolysis

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Q. 6 of Quiz- (Que-ID : 93)

Metabolite of chlordiazepoxide is

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  • Oxazepam
  • Demoxipam
  • All of these

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Q. 25 of Quiz- (Que-ID : 1208)

Open tender means -

  • Major tender
  • Moderate tender
  • Minor tender
  • None of these

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Q. 20 of Quiz- (Que-ID : 637)

In case of the schedule X drugs the prescription should be in:

  • Duplicate
  • Triplicate
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  • 5 copies

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Q. 10 of Quiz- (Que-ID : 97)

Efficiency of ball mill depends on

  • Rotational speed
  • Density of balls
  • Volume occupied by the balls
  • All of these

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Q. 7 of Quiz- (Que-ID : 1160)

Which type of surfactants have both hydrophobic and hydrophilic portion?

  • Anionic surfactants
  • Cationic surfactants
  • Non-ionic surfactants
  • Sodium soap

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Q. 5 of Quiz- (Que-ID : 1355)

Malonate is a competitive inhibitor of-

  • Succinate
  • Fumerate
  • Oxaloacetate
  • Aspaartate

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Q. 6 of Quiz- (Que-ID : 93)

Metabolite of chlordiazepoxide is

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  • Oxazepam
  • Demoxipam
  • All of these

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Q. 7 of Quiz- (Que-ID : 68)

Mephenamic acid is :

  • Selectiv COX-2 inhibitor
  • Antipiratics-analgesics
  • Fenamate non-selective cox-inhibitor
  • salicylates non-selective cox-inhibitor

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Q. 11 of Quiz- (Que-ID : 98)

Which of the following properties of a drug is affected by micronisation

  • Flow properties
  • Chemical stability
  • Therapeutic effectiveness
  • All of these

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Q. 8 of Quiz- (Que-ID : 1101)

Which one of these contain benzhydryl group?

  • Histamine
  • Diphenhydramine
  • Dimenhydrinate
  • Both option (b) and (c)

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Q. 22 of Quiz- (Que-ID : 1372)

The main ring structure is present in tryptophan is-

  • Indole
  • imidazole
  • furan
  • thiophane

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Q. 44 of Quiz- (Que-ID : 131)

HIV infection can be clinical controlled with

  • Ribavirin
  • Ganciclovir
  • Stavudine
  • Acyclovir

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Q. 10 of Quiz- (Que-ID : 653)

Oral anticoagulants act by antagonising the actions of -

  • Calcium ion
  • Prothrombin
  • Vitamin K
  • Fibrinogen

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Q. 16 of Quiz- (Que-ID : 1325)

The maximum number of members in public limited company is-

  • 20
  • 30
  • 50
  • unlimited

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Q. 40 of Quiz- (Que-ID : 127)

The constituent of essential oil is

  • Polyterpenoid
  • Tetraterpenoid
  • mono and sesquiterpenoid
  • Triterpenoid

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Q. 11 of Quiz- (Que-ID : 628)

Poisonous drugs are covered in 

  • Schedule F
  • Schedule E
  • Schedule Y
  • Schedule X

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Q. 14 of Quiz- (Que-ID : 101)

Which statement is not correct about levodopa?

  • In perkinsonism, phenothiazines reduce its efficacy
  • It is a prodrug
  • Pyridoxine reduces effect of levodopa in parkinsonism.
  • Domperidone blocks levodopa induced emesis and its therapeutic potential

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Q. 8 of Quiz- (Que-ID : 1492)

Which of the following is a prodrug

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  • Thiazine
  • Penicillin

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Q. 3 of Quiz- (Que-ID : 427)

Origin of KAVERI RIVER

  • Talakaveri in Western Ghats in Karnataka
  • Western Ghats near Mahabaleshwar in Maharashtra
  • Tamil nadu
  • Madhya pradesh

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Q. 21 of Quiz- (Que-ID : 1174)

In situ salt formation is a technique used in drug therapy to overcome -

  • Lack of solubility of salt
  • Poor absorption
  • Chemical instability
  • Complexation problems

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Q. 16 of Quiz- (Que-ID : 103)

Which of the following metabolite of cyclophosphamide is responsible for its anti-tumor actitivity?

  • Phosphoramide mustard
  • Acrolein
  • Aldophosphamide
  • 4-hydroxy cyclophosphamide

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Q. 8 of Quiz- (Que-ID : 1515)

The bladder trigone and prostatic muscles are relaxed by

  • Adrenergic α1 agonists
  • Adrenergic α1 antagonists
  • Adrenergic α2 antagonists
  • Adrenergic α2 agonists

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Directions : For each question, choose a correct option from given four options (A, B, C and D)

Q. 5 of Quiz- (Que-ID : 1219)

which one of these is used to increase the serum level of penicilline?

  • Aspirin
  • Ranitidine
  • Probenecid
  • Aluminium hydroxide gel

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Q. 1 of Quiz- (Que-ID : 1810)

Alupent is common brand name for-

  • Isoprenaline
  • Phenylephrine
  • Orciprenaline
  • Terbutaline

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Q. 5 of Quiz- (Que-ID : 1355)

Malonate is a competitive inhibitor of-

  • Succinate
  • Fumerate
  • Oxaloacetate
  • Aspaartate

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Q. 1 of Quiz- (Que-ID : 1351)

Proteins are precipitated by-

  • water
  • sodium hydroxide
  • formaldehyde
  • Trichloro acetic acid

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Q. 25 of Quiz- (Que-ID : 1405)

Triterpenoid saponins are present in-

  • Arjuna Bark
  • Black catechu
  • Bahera
  • none of the above

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Q. 28 of Quiz- (Que-ID : 1121)

Which one of these drug is a tricyclic antidepressant drug?

  • Tranylcypromine
  • Phenelzine
  • Isocarboxazide
  • Trimipramine

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Q. 22 of Quiz- (Que-ID : 3872)

An example of transferase enzyme

  • Lipase
  • Hexokinase
  • Esterase
  • Urease

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Q. 8 of Quiz- (Que-ID : 1515)

The bladder trigone and prostatic muscles are relaxed by

  • Adrenergic α1 agonists
  • Adrenergic α1 antagonists
  • Adrenergic α2 antagonists
  • Adrenergic α2 agonists

Discuss View Answer

Q. 14 of Quiz- (Que-ID : 1167)

Lozenges are also known as

  • Buccal tablets
  • Pessaries
  • Troches
  • Pastilles

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Q. 15 of Quiz- (Que-ID : 632)

The Pharmacy Council of India is constituted by the:

  • Central government
  • State government
  • Cabinet health minister
  • Legislative assembly

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Q. 20 of Quiz- (Que-ID : 1698)

Alum is added to bacterial toxins and toxoids to-

  • increase activity
  • precipitation of protein
  • Reduce toxicity
  • none of the above

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Q. 15 of Quiz- (Que-ID : 1081)

Mannitol acts as diuretic by-

  • Increasing the osmotic pressor in renal tubule
  • Increasing the rate if glomerular filtration
  • Inhibiting the reabsorption of sodium ion
  • None of the above

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Q. 13 of Quiz- (Que-ID : 489)

Melatonin is secreted by

  • Thymus gland
  • Adenophysis
  • Pineal gland
  • Adrenal gland

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Q. 9 of Quiz- (Que-ID : 3859)

Blood platelets are rich in

  • Carbohydrates
  • Cholesterol
  • Phospholipids and protein
  • Nucleic acids

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Q. 25 of Quiz- (Que-ID : 3925)

Main ring present in tryptophan is

  • Indole
  • Imidazole
  • Furan
  • Thiophane

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Q. 2 of Quiz- (Que-ID : 1125)

The latin word Pulvis consperus is used for

  • Powder
  • Paste
  • Ointment
  • Dusting powder

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Q. 2 of Quiz- (Que-ID : 1262)

Drugs that contraindicated in pregnancy-

  • Paracetamol
  • Colchicines
  • Indomethacin
  • Allopurinol

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Q. 2 of Quiz- (Que-ID : 1811)

Which of these hypnotic possess a muscle relaxant property?

  • Paraldehyde
  • Phenobarbitone
  • Barbitone
  • Diazepam

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Q. 6 of Quiz- (Que-ID : 1583)

The water soluble fuels which are overproduced during fasting or in untreated diabetes mellitus are called… . .

  • Melanin bodies
  • Ketone bodies
  • Glucose bodies
  • Citrate bodies

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