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One of the anti-rheumatic drug owes its activity due to its sulphide metabolites -
D. Pharma B. Pharma Pharmaceutical Organic Chemistry Bachelor of Pharmacy Diploma in Pharmacy
Q. 27 of Quiz-737 (Que-ID : 1120)
One of the anti-rheumatic drug owes its activity due to its sulphide metabolites -
- Indomethacin
- Sulindac
- Ketoprofen
- None of the above
Ans → (b)Sulindac
Explanation → Sulindac is related to indomethacin and has good anti-inflammatory action due to its sulphide metabolites.
This question is taken from this post → Practice Test #2 | Pharmaceutical Chemistry-II (Organic) - attemp/practice
More MCQs in - Practice Test #2 | Pharmaceutical Chemistry-II (Organic)
Q. 1 of Quiz-737 (Que-ID : 1064)
Commonly used amide type of local anesthetic agent is
- Procaine
- Benzocaine
- Amethocaine
- Lignocaine
Q. 2 of Quiz-737 (Que-ID : 1065)
Adrenaline (vasoconstrictor) is used with procaine hydrochloride injection to -
- Increase the activity of procaine
- Prolong the duration of anesthetic action
- Reduce the toxicity
- None of the above
Q. 3 of Quiz-737 (Que-ID : 1066)
Mogadone, hypnotic drug is brand name of -
- Lorazepam
- Nitrazepam
- Methaqualone
- None of the above
Q. 4 of Quiz-737 (Que-ID : 1097)
which one of these is not true for pilocarpine?
- It is naturally occuring alkaloid
- Used for teatment of glaucoma
- It is a cholinergic antagonist
- It contains imidazole nucleus
Q. 5 of Quiz-737 (Que-ID : 1098)
Pseudoephedrine differs from ephedrine in -
- Chemical structure
- Isomerism
- Activity
- Activity and isomerism
Q. 6 of Quiz-737 (Que-ID : 1099)
Digoxin contains hydroxyl groups at position-
- 3 and 12
- 3 and 14
- 3, 12 and 14
- 3, 12 and 15
Q. 7 of Quiz-737 (Que-ID : 1100)
Lasix is the common brand name for
- Furosemide
- Ethacrynic acid
- Sprinolactone
- Hydrochlorthiazide
Q. 8 of Quiz-737 (Que-ID : 1101)
Which one of these contain benzhydryl group?
- Histamine
- Diphenhydramine
- Dimenhydrinate
- Both option (b) and (c)
Q. 9 of Quiz-737 (Que-ID : 1102)
The piperidine ring skeleton is present in
- Pantazocine
- Levorphan
- Pethidine
- Nalorphine
Q. 10 of Quiz-737 (Que-ID : 1103)
Paracetamol is marketed as -
- Tylenol
- Calpol
- Crocin
- All of the above
Q. 11 of Quiz-737 (Que-ID : 1104)
Which drug has the antiserotonin activity?
- Cyproheptadine
- Promethazine
- Terfinadine
- All of the above
Q. 12 of Quiz-737 (Que-ID : 1105)
Which is the non acidic anti-inflammatory agent?
- Oxyphenbutazone
- Ibuprofen
- Piroxicam
- Nabumetone
Q. 13 of Quiz-737 (Que-ID : 1106)
Which one of these antitubercular drugs contain pyridine nucleus?
- Isoniazid
- Pyrizinamide
- Ethionamide
- Cycloserine
Q. 15 of Quiz-737 (Que-ID : 1108)
The chemical name for metronidazole is
- 2-methyl-5- nitro-1H-imidazole-1-ethanol
- 2-methyl- 5-nitro-1H-imidazole-1-methanol
- 2-methyl-5-nitro-2H-imidazole-1-ethanol
- 2-methyl-5-nitro-1H-imidazole-1- methanol
Q. 16 of Quiz-737 (Que-ID : 1109)
The clofibrate is used in -
- type iii hyperlipoproteinemia
- Hypertension
- vascular problems
- Raynauds disease
Q. 17 of Quiz-737 (Que-ID : 1110)
Which of these has azocinyl moiety?
- Guanethidine
- Clofibrate
- Quinidine
- Quinine
Q. 18 of Quiz-737 (Que-ID : 1111)
The muscle relaxant 'meprobamate' is a derivative of -
- Dicarbamate
- Dioic acid
- Diamine
- Diol
Q. 19 of Quiz-737 (Que-ID : 1112)
Which one of these is not a mydriatic agent?
- Atropine
- Homatropine
- Tropicamide
- Hyoscyamine
Q. 20 of Quiz-737 (Que-ID : 1113)
The chemical name 1,1-oxybisethane belongs to -
- Dimethyl ether
- Diethyl ether
- Methyl ethyl ether
- Cyclopropyl ether
Q. 21 of Quiz-737 (Que-ID : 1114)
The pentothal sodium is a -
- Local anesthetic
- Intravenous anesthetic
- General anesthetic
- Hypnotic
Q. 22 of Quiz-737 (Que-ID : 1115)
The prefix 'sila' is used for
- Sulphur
- Silicon
- Selenium
- None of the above
Q. 23 of Quiz-737 (Que-ID : 1116)
Which one of these sulpha drug possess guanidine, used in bacillary dysentery?
- Sulphadiazine
- Sulphadimidine
- Sulphaguanidine
- Sulphasomidine
Q. 24 of Quiz-737 (Que-ID : 1117)
The basic ring present in estradiol (female sex hormone) -
- 5 α - androstane
- 5 α - estrane
- 5 α - pregnane
- None of the above
Q. 25 of Quiz-737 (Que-ID : 1118)
Two polypeptide chain in insulin is linked together by -
- Hydrogen bond
- Disulphide bond
- Covalent bond
- None of the above
Q. 26 of Quiz-737 (Que-ID : 1119)
Acetazolamide, carbonic anhydrase inhibitor, is used in
- Glaucoma
- Hypertension
- Bacterial infection
- None of the above
Q. 27 of Quiz-737 (Que-ID : 1120)
One of the anti-rheumatic drug owes its activity due to its sulphide metabolites -
- Indomethacin
- Sulindac
- Ketoprofen
- None of the above
Q. 28 of Quiz-737 (Que-ID : 1121)
Which one of these drug is a tricyclic antidepressant drug?
- Tranylcypromine
- Phenelzine
- Isocarboxazide
- Trimipramine
Q. 29 of Quiz-737 (Que-ID : 1122)
Aminophylline is salt of ethylenediamine with -
- Theophylline
- Caffeine
- Theobromine
- None of the above
Q. 30 of Quiz-737 (Que-ID : 1123)
The diagnostic agent propyliodone is used for -
- Urography
- Bronchography
- Arteriography
- Myelography
More MCQs In - D. Pharma B. Pharma Pharmaceutical Organic Chemistry Bachelor of Pharmacy Diploma in Pharmacy
Q. 3 of Quiz- (Que-ID : 644)
Levodopa is amino acid precursor of -
- Adrenaline
- Dopamine
- Norepinephrine
- All of these
Q. 2 of Quiz- (Que-ID : 675)
Ampoules generally contain
- Single dose parentral product
- multiple dose parental product
- Two or three doses
- none of these
Directions : For each question, choose a correct option from given four options (A, B, C and D)
Q. 17 of Quiz- (Que-ID : 1231)Texas urinary catheter is designed for-
- female patients
- male patients
- elderly patients
- small children
Q. 13 of Quiz- (Que-ID : 630)
Schedule F2 of Drug and Cosmetic act is related to -
- Standards for opthalmic preparations
- Standards for surgical dressings
- Standards for sterilized umbilical tapes
- Standards for disinfectant fluids
Q. 10 of Quiz- (Que-ID : 1044)
Name the hormone involved in regulation of calcium?
- Growth hormone
- Thyroid hormone
- Insulin hormone
- PTH (parathyroid hormone)
Q. 16 of Quiz- (Que-ID : 1109)
The clofibrate is used in -
- type iii hyperlipoproteinemia
- Hypertension
- vascular problems
- Raynauds disease
Directions : For each question, choose a correct option from given four options (A, B, C and D)
Q. 28 of Quiz- (Que-ID : 1242)The antileprotic drug clofazimine causes-
- nephrotoxicity
- photosensitivity
- hepatotoxicity
- none of the above
Q. 3 of Quiz- (Que-ID : 1644)
Rheumatoid Arthritis is a example of
- Type I Hypersnsitivity
- Type II Hypersnsitivity
- Type III Hypersnsitivity
- Type IV Hypersnsitivity
Q. 7 of Quiz- (Que-ID : 1100)
Lasix is the common brand name for
- Furosemide
- Ethacrynic acid
- Sprinolactone
- Hydrochlorthiazide
Q. 8 of Quiz- (Que-ID : 1191)
The business financial year in India ends on -
- March 31st
- December 31st
- July 31st
- March 31st and December 31st
Directions : .
Q. 2 of Quiz- (Que-ID : 1496)The following cotransmitter is most probably involved in mediating nonadrenergic-noncholinergic (NANC) relaxation of the gut
- Nitric oxide (NO)
- Adenosine
- Neuropeptide Y (NPY)
- Kallidin
Q. 3 of Quiz- (Que-ID : 619)
'Magic remedies Act' was passed in -
- April 1954
- May 1950
- October 1948
- June 1959
Q. 12 of Quiz- (Que-ID : 1078)
Hyoscine (scopolamine) differs structurally from atropine -
- Hyoscine is not a ester
- Hyoscine is an ester of different alcohol and tropic acid
- Hyoscine possesses epoxide linkage between carbon 6 and 7
- None of the above
Q. 2 of Quiz- (Que-ID : 1680)
Most widely used anticaries agent is-
- sodium bicarbonate
- sodium carbonate
- sodium fluoride
- acacia
Q. 8 of Quiz- (Que-ID : 459)
Which enzyme catalyse the linking of two compounds?
- Transferase
- Isomerase
- Ligase
- Lyases
Q. 29 of Quiz- (Que-ID : 1152)
Which one of these is an example of 'ayurvedic drug?
- Arks
- Bhasmas
- Asavas
- All of these
Q. 21 of Quiz- (Que-ID : 1174)
In situ salt formation is a technique used in drug therapy to overcome -
- Lack of solubility of salt
- Poor absorption
- Chemical instability
- Complexation problems
Q. 3 of Quiz- (Que-ID : 1353)
Ninhydrin oxidatively decarboxylates α-amino acids to-
- CO2
- H2O,CO2
- CO2,NH3
- NH3
Q. 6 of Quiz- (Que-ID : 679)
Micrometrics deals with the study of
- Powders
- Micropores
- small particles
- metric system of measurements
Q. 7 of Quiz- (Que-ID : 1491)
High plasma protein binding
- Increases volume of distribution of the drug
- Generally makes the drug long acting
- Facilitates glomerular filtration of the drug
- Minimises drug interactions
Q. 15 of Quiz- (Que-ID : 688)
Tablet is film coated with
- cellulose acetate phthalate
- Cellulose
- Hydroxy propyle methyle cellulose
- carboxy methyle cellulose
Q. 5 of Quiz- (Que-ID : 1677)
_______ is expressed in both the intestinal epithelium and the kidney.
- CYP378A
- CYP4B2
- CYP3A4
- CYP256
Q. 28 of Quiz- (Que-ID : 1378)
The cyclic fatty acid, Chaulmoogric acid is used in the treatment of-
- T.B.
- ulcers
- Leprosy
- Goiter
Q. 8 of Quiz- (Que-ID : 8)
Which one of these is a drying oil?
- Linseed Oil
- Castor Oil
- Coconut Oil
- Seasome Oli
Q. 26 of Quiz- (Que-ID : 1376)
Pantohenic acid is also known as-
- vitamin B1
- vitamin B5
- vitamin B2
- Vitamin B12
Q. 24 of Quiz- (Que-ID : 1702)
The lead acetate cotton wool is used in limit test for arsenic to-
- Make the arsine gas
- Develop the yellow colour
- Trap the hydrogen sulphide gas
- none of the above
Directions :
Which of the following organs is innervated only by parasympathetic nerves
- Sweat glands
- Ciliary muscle
- Iris muscles
- Splenic capsule
Q. 17 of Quiz- (Que-ID : 1170)
Youngs formula for dose calculation is -
- \({Age \ in \ years \over Age \ in \ years + 12} × adult dose\)
- \({Age \over 20} × adult \ dose\)
- Weight of the child in lbs/150 × adult dose
- Age in months / 150 × adult dose
Q. 14 of Quiz- (Que-ID : 657)
Nystatin is principally effective in:
- Candidia albicans
- Blastomyces
- Cryptococcus histoplasma
- All of the above
Q. 9 of Quiz- (Que-ID : 1476)
Substances which anesthetize the restricted area without making subject unconscious…
- Local anaesthetic
- Antiemetics
- General anaesthetic
- Analgesics
Q. 8 of Quiz- (Que-ID : 1837)
Measles is caused by-
- Variola virus
- Rubeola virus
- Varicella zoster
- Herpes virus
Q. 14 of Quiz- (Que-ID : 1197)
Drug samples worth Rs. 5,000 were distributed to physicians. The amount should be debited to -
- Sales account
- Samples account
- Advertisement account
- None of the above
Q. 7 of Quiz- (Que-ID : 1628)
Which of the above is not a cellular adaptation?
- Hyperplasia
- Hypertrophy
- Hypoplasia
- Metaplasia
Q. 7 of Quiz- (Que-ID : 1638)
Prostaglandins (PGs) are
- LOX pathway product
- Cytokinines
- Vasoactiveamines
- COX pathway product
Q. 10 of Quiz- (Que-ID : 1688)
Iodine dissolves in water with the addition of-
- Sodium chloride
- Sulphur
- Potassium iodide
- Calcium carbonate
Q. 8 of Quiz- (Que-ID : 1686)
Antimony potassium tartarate is used as-
- Antidote
- Emetic
- Astringent
- Buffer
Q. 11 of Quiz- (Que-ID : 1104)
Which drug has the antiserotonin activity?
- Cyproheptadine
- Promethazine
- Terfinadine
- All of the above
Q. 10 of Quiz- (Que-ID : 1360)
Milky type colour of urine is due to the presence of-
- Albumins
- haemoglobin
- Fatty acid
- Nephritis
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