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One Liner

The enhancement of action of one drug by another inactive drug

Potentiation (supra-additive effect)
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This question belongs to the set "Revision of Pharmacology, some basic points (one liners)". Click below to read detailed notes and attempt the full quiz.

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  • A Increases volume of distribution of the drug
  • B Generally makes the drug long acting
  • C Facilitates glomerular filtration of the drug
  • D Minimises drug interactions
  • A Is more painful
  • B Produces faster response
  • C Is unsuitable for depot preparations
  • D Carries greater risk of anaphylactic reaction
  • A Tolerance
  • B Physical dependence
  • C Psychological dependence
  • D Idiosyncrasy
  • A Nature of the base used in the formulation
  • B Lipid solubility of the drug
  • C Molecular weight of the drug
  • D Site of application
  • A Dapsone
  • B Meperidine
  • C Phenytoin
  • D Chlorpheniramine
Explanation: N-oxidation is involved in the metabolism of dapsone, meperidine and chloramphenicol. Metabolism of phenytoin involves oxidative Ndealkylation.
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