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One Liner

Drugs that are used for the diagnosis, treatment or prevention of rare diseases

Orphan drug
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Try These Similar MCQs

  • A Increases volume of distribution of the drug
  • B Generally makes the drug long acting
  • C Facilitates glomerular filtration of the drug
  • D Minimises drug interactions
  • A Dapsone
  • B Meperidine
  • C Phenytoin
  • D Chlorpheniramine
Explanation: N-oxidation is involved in the metabolism of dapsone, meperidine and chloramphenicol. Metabolism of phenytoin involves oxidative Ndealkylation.
  • A Is more painful
  • B Produces faster response
  • C Is unsuitable for depot preparations
  • D Carries greater risk of anaphylactic reaction
  • A It has additional α1 blocking property
  • B It is a selective βS1 blocker
  • C It does not undergo first pass metabolism
  • D All of the above
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