Commonly used amide type of local anesthetic agent is

d) Lignocaine | Lignocaine is most commonly used anesthetic. It is commonly known as xylocaine and its belongs to amide class.

Adrenaline (vasoconstrictor) is used with procaine hydrochloride injection to -

b) Prolong the duration of anesthetic action | Adrenaline is a adrenergic drug, causes vasoconstriction so decrease area of absorption of drug.

Mogadone, hypnotic drug is brand name of -

b) Nitrazepam | Nitrazepam is a hypnotic drug under benzodiazepines class is available in the market under the brand name of mogadone, nitravet, sedamon, hypnotext etc. it is used for treatment of insomnia (sleeping desorder).

which one of these is not true for pilocarpine?

c) It is a cholinergic antagonist | Pilocarpine is not a cholinergic antagonist.

Pseudoephedrine differs from ephedrine in -

d) Activity and isomerism | Pseudoephedrine is a diasteromer of of ephedrine. The activity us also different from ephedrine.

Lasix is the common brand name for

a) Furosemide | Furosemide is a loop diuretic (ceiling diuretics) and available under the brand names lasix, furid, frumex, etc.

Which one of these contain benzhydryl group?

d) Both option (b) and (c) | Diphenhydramine and dimenhydrinate both contain benzhydryl group. (Below is the image showing the structure of diphenhydramine HCl containing benzhydryl group.)

The piperidine ring skeleton is present in

c) Pethidine | Pethidine (mepridine) is a synthetic opioid analgesic of piperidine class.

Paracetamol is marketed as -

d) All of the above | Paracetamol (acetaminophen) is available under the brand names tylenol, calpol, Crocin, PCM, dolo etc.

Which drug has the antiserotonin activity?

a) Cyproheptadine | Cyproheptadine (periactin, peritol, etc.) is an antihistaminic with additional anti cholinergic , antiserotonergic, and local anesthetic properties.

Which is the non acidic anti-inflammatory agent?

d) Nabumetone | Nabumetone is a nonacidic NSAID prodrug that is rapidly metabolized in the liver to the active metabolite, 6-methoxy-2-naphthyl acetic acid. It is available with the brand name nabuflam.

Which one of these antitubercular drugs contain pyridine nucleus?

c) Ethionamide | Ethionamide contains pyridine nucleus.

Erythromycin will be unstable at pH

c) 4 | Erythromycin is unstable in acidic medium (pH < 7).

The chemical name for metronidazole is

a) 2-methyl-5- nitro-1H-imidazole-1-ethanol | Metronidazole is 2-methyl-5- nitro-1H-imidazole-1-ethanol and it is antibacterial and antiprotozoal agent. Brand name - flagyl

The clofibrate is used in -

a) type iii hyperlipoproteinemia | Clofibrate is a lipid lowering agent indicated in hyperlipoproteinemia (type III).&nbsp;&nbsp;

Which of these has azocinyl moiety?

a) Guanethidine | Guanethidine is an antihypertensive drug. It has azocinyl moiety in its structure.

The muscle relaxant 'meprobamate' is a derivative of -

a) Dicarbamate | Meprobamate is dicarbamate. it is used as skeletal muscle relaxant.

Which one of these is not a mydriatic agent?

d) Hyoscyamine | Hyoscyamine is not a mydriatic agent. Mydriatic agents are drugs which can dilate the pupil of eye. Atropine, homatropine, tropicamide are tropane alkaloids and mydriatic agents. Hyoscyamine is also a tropane alkaloid but it is not a mydriatic agent.

The chemical name 1,1-oxybisethane belongs to -

b) Diethyl ether | Diethyl ether is ethoxy ether or 3-oxapentane or 1,1-oxybisethane.

The pentothal sodium is a -

b) Intravenous anesthetic | Pentothal sodium (thiopental sodium) is a short acting barbiturates and used as Intravenous (i.v.) Anesthetic agents.

The prefix 'sila' is used for

b) Silicon | Silicon is represented by the prefix 'sila'.

Which one of these sulpha drug possess guanidine, used in bacillary dysentery?

c) Sulphaguanidine | Sulphaguanidine is used in bacillary dysentery. It is a veterinary drug.

The basic ring present in estradiol (female sex hormone) -

b) 5 α - estrane | The basic steroidal ring in estradiol is 5 &alpha; - estrane.

Two polypeptide chain in insulin is linked together by -

b) Disulphide bond | Insulin is a dimer of an A- chain and a B- chain, which are linked together by disulphide bond.

Acetazolamide, carbonic anhydrase inhibitor, is used in

a) Glaucoma | Acetazolamide (diamox) is used in glaucoma to reduce intra-ocular pressure.

One of the anti-rheumatic drug owes its activity due to its sulphide metabolites -

b) Sulindac | Sulindac is related to indomethacin and has good anti-inflammatory action due to its sulphide metabolites.

Which one of these drug is a tricyclic antidepressant drug?

d) Trimipramine | Imipramine, chlopramine and trimipramine are Tricyclic antidepressant (TCA) drugs.

Aminophylline is salt of ethylenediamine with -

a) Theophylline | Aminophylline is a compound of theophylline and ethylene di amine in 2:1 ratio. It is a bronchodilator containing 2 parts of theophylline and 1 part of ethylene di amine.

The diagnostic agent propyliodone is used for -

b) Bronchography | Propyliodone (Dionosil) is used as contrast media in bronchography.

Digoxin contains hydroxyl groups at position-

Q: Digoxin contains hydroxyl groups at position-

c) 3, 12 and 14 | Digoxin has 3 hydroxyl groups in the steroidal nucleus at 3, 12 and 14 positions.

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Q.6. Digoxin contains hydroxyl groups at position-

3 and 12
3 and 14
3, 12 and 14
3, 12 and 15

Answer: (c) 3, 12 and 14
Explanation: Digoxin has 3 hydroxyl groups in the steroidal nucleus at 3, 12 and 14 positions.

Practice Test #2 | Pharmaceutical Chemistry-II (Organic)

30 Questions 557 Attempts 18.18K Seen

This is practice test no. 2 in pharmaceutical chemistry test series.
This practice test includes objective questions (MCQs) from pharmaceutical organic chemistry (pharma chemistry 2) for D.Pharma and B.pharma students. These questions are very helpful for competitive as well as (objective questions based) university exams. Start Test without Login in
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Q.No.	Que title	Option 1 (a)	Option 2 (b)	Option 3 (c)	Option 4 (d)
1	Commonly used amide type of local anesthetic agent is	Procaine	Benzocaine	Amethocaine	Lignocaine
2	Adrenaline (vasoconstrictor) is used with procaine hydrochloride injection to -	Increase the activity of procaine	Prolong the duration of anesthetic action	Reduce the toxicity	None of the above
3	Mogadone, hypnotic drug is brand name of -	Lorazepam	Nitrazepam	Methaqualone	None of the above
4	which one of these is not true for pilocarpine?	It is naturally occuring alkaloid	Used for teatment of glaucoma	It is a cholinergic antagonist	It contains imidazole nucleus
5	Pseudoephedrine differs from ephedrine in -	Chemical structure	Isomerism	Activity	Activity and isomerism
6	Digoxin contains hydroxyl groups at position-	3 and 12	3 and 14	3, 12 and 14	3, 12 and 15
7	Lasix is the common brand name for	Furosemide	Ethacrynic acid	Sprinolactone	Hydrochlorthiazide
8	Which one of these contain benzhydryl group?	Histamine	Diphenhydramine	Dimenhydrinate	Both option (b) and (c)
9	The piperidine ring skeleton is present in	Pantazocine	Levorphan	Pethidine	Nalorphine
10	Paracetamol is marketed as -	Tylenol	Calpol	Crocin	All of the above
11	Which drug has the antiserotonin activity?	Cyproheptadine	Promethazine	Terfinadine	All of the above
12	Which is the non acidic anti-inflammatory agent?	Oxyphenbutazone	Ibuprofen	Piroxicam	Nabumetone
13	Which one of these antitubercular drugs contain pyridine nucleus?	Isoniazid	Pyrizinamide	Ethionamide	Cycloserine
14	Erythromycin will be unstable at pH	8	9	4	None of the above
15	The chemical name for metronidazole is	2-methyl-5- nitro-1H-imidazole-1-ethanol	2-methyl- 5-nitro-1H-imidazole-1-methanol	2-methyl-5-nitro-2H-imidazole-1-ethanol	2-methyl-5-nitro-1H-imidazole-1- methanol
16	The clofibrate is used in -	type iii hyperlipoproteinemia	Hypertension	vascular problems	Raynauds disease
17	Which of these has azocinyl moiety?	Guanethidine	Clofibrate	Quinidine	Quinine
18	The muscle relaxant 'meprobamate' is a derivative of -	Dicarbamate	Dioic acid	Diamine	Diol
19	Which one of these is not a mydriatic agent?	Atropine	Homatropine	Tropicamide	Hyoscyamine
20	The chemical name 1,1-oxybisethane belongs to -	Dimethyl ether	Diethyl ether	Methyl ethyl ether	Cyclopropyl ether
21	The pentothal sodium is a -	Local anesthetic	Intravenous anesthetic	General anesthetic	Hypnotic
22	The prefix 'sila' is used for	Sulphur	Silicon	Selenium	None of the above
23	Which one of these sulpha drug possess guanidine, used in bacillary dysentery?	Sulphadiazine	Sulphadimidine	Sulphaguanidine	Sulphasomidine
24	The basic ring present in estradiol (female sex hormone) -	5 α - androstane	5 α - estrane	5 α - pregnane	None of the above
25	Two polypeptide chain in insulin is linked together by -	Hydrogen bond	Disulphide bond	Covalent bond	None of the above
26	Acetazolamide, carbonic anhydrase inhibitor, is used in	Glaucoma	Hypertension	Bacterial infection	None of the above
27	One of the anti-rheumatic drug owes its activity due to its sulphide metabolites -	Indomethacin	Sulindac	Ketoprofen	None of the above
28	Which one of these drug is a tricyclic antidepressant drug?	Tranylcypromine	Phenelzine	Isocarboxazide	Trimipramine
29	Aminophylline is salt of ethylenediamine with -	Theophylline	Caffeine	Theobromine	None of the above
30	The diagnostic agent propyliodone is used for -	Urography	Bronchography	Arteriography	Myelography

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