Pharmaceutics Questions

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Specific case of drug embedding in insoluble excipients (typically in a polymer) in order to achieve extended release.

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Small sterile usually polymeric matrices, pellets, or particles for insertion or implanting into the body by surgical means or by injection to help achieve sustained release.

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Emulsions in which the dispersed droplets are in the micron-size range.


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Number that expresses the reduction in the numbers of a microorganism, brought about by a sterilizaion process.

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Formation of microparticles encapsulating a drug.

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Reversible formation of association colloids from surfactants in nonpolar solvents leads to aggregates termed inverted (or inverse, reverse, or reversed) micelles.

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A Solid spherical particles of micron-size range, used as matrix dosage forms.

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Artificial spherical lipid bilayer droplet formed mainly from phospholipids having a core of water phase, small enough to form a relatively stable dispersion in aqueous media and with potential use in drug delivery.


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Concentration of a drug that must be achieved in the plasma before any desired therapeutic or pharmacological effect can be obtained.

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Initial, typically larger than the maintenance dose of a drug given to a patient at the start of pharmacotherapy.

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Lowest concentration of an antibacterial drug necessary to inhibit the growth of a microorganism.

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Tablet, which does not contain a disintegrant and which is sucked to dissolve in the mouth to produce either a local (e.g., antiseptic) or systemic (e.g., vitamins) effect.

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Release of a drug from a dosage form that it is not immediate

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Used as processing aid in tablet and capsule manufacturing, to facilitate the movement of the formulation into the dye and punch and to reduce the energy of compression.

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Usually water or low-molecular-weight alcohols or compounds, used in topical applications and in wet granulation, for the production of tablets.

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Dosage form comprising several elements (e.g., microspheres or coated pellets) dif- fering in the rate of drug release.

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Consists of several different layers that are compressed on top of each other, to form a single tablet composed of two or more layers.

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Device that disperses liquids to aerosols for therapeutic use by inhalation through a mask.

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Greasy, semi-solid preparation for external application, often anhydrous, containing dissolved or dispersed medicaments.

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Kinetic model, where the whole body is thought of as a single compartment in which a substance is dis- tributed rapidly, achieving an equilibrium between blood and tissue immediately.