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One Liner

The aspect of medicine concerned with the treatment of diseases

Therapeutics

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  • A It has additional α1 blocking property
  • B It is a selective βS1 blocker
  • C It does not undergo first pass metabolism
  • D All of the above
  • A Dapsone
  • B Meperidine
  • C Phenytoin
  • D Chlorpheniramine
Explanation: N-oxidation is involved in the metabolism of dapsone, meperidine and chloramphenicol. Metabolism of phenytoin involves oxidative Ndealkylation.
  • A Increases volume of distribution of the drug
  • B Generally makes the drug long acting
  • C Facilitates glomerular filtration of the drug
  • D Minimises drug interactions
  • A Nature of the base used in the formulation
  • B Lipid solubility of the drug
  • C Molecular weight of the drug
  • D Site of application

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