Initial, typically larger than the maintenance dose of a drug given to a patient at the start of pharmacotherapy.
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One Liner
Time required to achieve the minimum effective plasma concentration following administration of the dosage form.
onset of drug action
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Kinetic model, where the whole body is thought of as a single compartment in which a substance is dis- tributed…
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Transition of a solid crystalline phase to another phase having the same chemical composition but a dif- ferent crystal structure.
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Exploratory activity that begins early in pharmaceutics, involving studies designed to determine the compatibility of excipients with the active substance…
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Dry solid material consisting of many, usually free flowing, fine particles.
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Solid material that exists at least in two different molecular arrangements, i.e., distinctly different crystal species.
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Process of enclosing a drug in a (micro or nano) particle (capsule, liposome, polymer).
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Defined for powders used pharmaceutically, according to particle sizes.
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